2019
Differential responses of epithelial cells from urinary and biliary tract to eggs of Schistosoma haematobium and S. mansoni
Nacif-Pimenta R, da Silva Orfanó A, Mosley IA, Karinshak SE, Ishida K, Mann VH, Coelho PMZ, da Costa JMC, Hsieh MH, Brindley PJ, Rinaldi G. Differential responses of epithelial cells from urinary and biliary tract to eggs of Schistosoma haematobium and S. mansoni. Scientific Reports 2019, 9: 10731. PMID: 31341177, PMCID: PMC6656753, DOI: 10.1038/s41598-019-46917-y.Peer-Reviewed Original ResearchConceptsSchistosome eggsEpithelial cellsS. haematobiumS. mansoniUrothelial cellsS. mansoni eggsS. haematobium eggsSquamous cell carcinomaCell proliferative responsesGroup 1 carcinogenHepatointestinal schistosomiasisPeriportal fibrosisBiliary tractMansoni eggsCell carcinomaChronic infectionUrogenital schistosomiasisEstrogen receptorProliferative responseDefinitive causeSchistosoma haematobiumNormal urotheliumHuman epithelial cellsMesenchymal transitionS. japonicum
2012
Schistosoma mansoni in Susceptible and Resistant Snail Strains Biomphalaria tenagophila: In Vivo Tissue Response and In Vitro Hemocyte Interactions
Nacif-Pimenta R, de Mattos AC, da Silva Orfanó A, Barbosa L, Pimenta PF, Coelho PM. Schistosoma mansoni in Susceptible and Resistant Snail Strains Biomphalaria tenagophila: In Vivo Tissue Response and In Vitro Hemocyte Interactions. PLOS ONE 2012, 7: e45637. PMID: 23049828, PMCID: PMC3458097, DOI: 10.1371/journal.pone.0045637.Peer-Reviewed Original ResearchConceptsS. mansoniInternal defense systemNon-self molecular patternsResistant snailsSchistosoma mansoniResistant strainsImmune defense mechanismsBiomphalaria tenagophilaThreat of infectionB. tenagophilaSnail strainsInitial infectionSusceptible snailsParasitic diseasesInfectionImmune defense responseMansoniMolecular patternsSusceptible strainsTissue responseTime courseCellular reactionsHost cellsCellular defenseVivo tissue response