Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment
Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Townsend R, Peixoto A, Wilson FP. Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment. Journal Of Clinical Hypertension 2022, 24: 339-349. PMID: 35174627, PMCID: PMC8925013, DOI: 10.1111/jch.14431.Peer-Reviewed Original ResearchConceptsSevere hypertensionBlood pressure responseBP elevationUntreated patientsCox proportional hazards modelRetrospective cohort studyPressure responseProportional hazards modelAntihypertensive treatmentInpatient hypertensionMore comorbiditiesPossible overtreatmentHospitalized adultsCohort studyHypertension prevalenceArterial pressureHospitalized patientsTreatment guidelinesHypertensionGreater rateHazards modelPatientsAntihypertensivesTreatmentAdmissionExcessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension
Hanna J, Ghazi L, Yamamoto Y, Simonov M, Shah T, Wilson F, Peixoto A. Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension. American Journal Of Hypertension 2022, 35: 433-440. PMID: 35038322, PMCID: PMC9088839, DOI: 10.1093/ajh/hpac004.Peer-Reviewed Original ResearchConceptsAsymptomatic severe hypertensionBlood pressure responseSevere hypertensionHospitalized patientsPressure responseExcessive blood pressure responseMean arterial pressure reductionMAP reductionAcute kidney injuryBlood pressure declineArterial pressure reductionHours of administrationClonidine doseKidney injuryPrimary endpointAdverse eventsIschemic eventsBlood pressureIll patientsClinical groundsMedian timePatient sexFemale sexVascular diseaseMultivariable model