2024
Hypertension Control During the Coronavirus Disease 2019 Pandemic
Korves C, Peixoto A, Lucas B, Davies L, Weinberger D, Rentsch C, Vashi A, Young-Xu Y, King J, Asch S, Justice A. Hypertension Control During the Coronavirus Disease 2019 Pandemic. Medical Care 2024, 62: 196-204. PMID: 38284412, PMCID: PMC10922611, DOI: 10.1097/mlr.0000000000001971.Peer-Reviewed Original ResearchConceptsHypertension controlFollow-up intervalPrimary care clinic visitsFollow-up lengthVeterans Health AdministrationControlled hypertensionUncontrolled hypertensionGeneralized estimating equationsCohort of individualsStudy inclusion criteriaHealth careHealth AdministrationLonger follow-up intervalsBlood pressure measurementsAssessed associationsClinic visitsInclusion criteriaDecreased likelihoodEstimating equationsPrepandemic periodLow likelihoodCoronavirus diseaseFollow-upHypertensionIndividuals
2022
Effect of intravenous antihypertensives on outcomes of severe hypertension in hospitalized patients without acute target organ damage
Ghazi L, Li F, Simonov M, Yamamoto Y, Nugent J, Greenberg J, Bakhoum C, Peixoto A, Wilson F. Effect of intravenous antihypertensives on outcomes of severe hypertension in hospitalized patients without acute target organ damage. Journal Of Hypertension 2022, 41: 288-294. PMID: 36583354, PMCID: PMC9799038, DOI: 10.1097/hjh.0000000000003328.Peer-Reviewed Original ResearchConceptsAcute target organ damageTarget organ damageSevere hypertensionOrgan damageIntravenous antihypertensivesBP elevationClinical outcomesMyocardial injuryTarget end-organ damageOverlap propensity scoreSevere BP elevationAcute kidney injuryBlood pressure reductionEnd-organ damageRisk of strokeInpatient hypertensionCardiovascular eventsIndex hospitalizationKidney injuryRetrospective studyHypertensionAntihypertensivesHospitalizationCox modelPatientsBlood pressure response to commonly administered antihypertensives for severe inpatient hypertension
Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto AJ, Wilson FP. Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension. PLOS ONE 2022, 17: e0265497. PMID: 35385506, PMCID: PMC8985959, DOI: 10.1371/journal.pone.0265497.Peer-Reviewed Original ResearchConceptsHTN developmentSevere hypertensionOral hydralazineOral carvedilolIntensive care unit patientsBlood pressure elevationCare unit patientsAssociation of treatmentSingle healthcare systemAntihypertensive treatmentCommon antihypertensivesInpatient hypertensionOral amlodipinePrescribed antihypertensivesOral metoprololClinical characteristicsCohort studyUnit patientsBP responseHospitalized patientsPressure elevationBP changesLower BPHypertensionHydralazineSevere inpatient hypertension prevalence and blood pressure response to antihypertensive treatment
Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Townsend R, Peixoto A, Wilson FP. Severe inpatient hypertension prevalence and blood pressure response to antihypertensive treatment. Journal Of Clinical Hypertension 2022, 24: 339-349. PMID: 35174627, PMCID: PMC8925013, DOI: 10.1111/jch.14431.Peer-Reviewed Original ResearchConceptsSevere hypertensionBlood pressure responseBP elevationUntreated patientsCox proportional hazards modelRetrospective cohort studyPressure responseProportional hazards modelAntihypertensive treatmentInpatient hypertensionMore comorbiditiesPossible overtreatmentHospitalized adultsCohort studyHypertension prevalenceArterial pressureHospitalized patientsTreatment guidelinesHypertensionGreater rateHazards modelPatientsAntihypertensivesTreatmentAdmission
2020
Chapter 46 Approach to the Patient with Hypertensive Nephrosclerosis
Peixoto A, Bakris G. Chapter 46 Approach to the Patient with Hypertensive Nephrosclerosis. 2020, 737-752. DOI: 10.1016/b978-0-12-815876-0.00046-2.Peer-Reviewed Original ResearchHypertensive nephrosclerosisEnd-stage renal diseaseBlood pressure controlChronic kidney diseaseRenin-angiotensin systemMechanism of injuryArteriolar myogenic responseNonmalignant hypertensionTuft collapseBase therapyImpaired autoregulationUnderlying diseaseRenal diseaseInterstitial fibrosisKidney diseaseGlomerular hypertensionUrine sedimentMyogenic responsePressure controlHypertensionGene mutationsDiseaseNephrosclerosisPatientsProteinuria
2019
Acute Severe Hypertension
Peixoto AJ. Acute Severe Hypertension. New England Journal Of Medicine 2019, 381: 1843-1852. PMID: 31693807, DOI: 10.1056/nejmcp1901117.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAntihypertensive AgentsBlood PressureBlood Pressure DeterminationCerebral HemorrhageElectrocardiographyFemaleHumansHypertensionHypertrophy, Left VentricularInfusions, IntravenousIntensive Care UnitsMedication AdherenceMiddle AgedPosterior Leukoencephalopathy SyndromePractice Guidelines as Topic
2018
Arterial stiffness in elderly patients with normotension and hypertension in Brazil
de Mendonça G, de Souza D, de Alvarenga Cunha Brunelli A, de Oliveira Peres C, Freitas EGB, Lacerda GN, Dorneles MC, Peixoto AJ, Ferreira‐Filho S. Arterial stiffness in elderly patients with normotension and hypertension in Brazil. Journal Of Clinical Hypertension 2018, 20: 1285-1293. PMID: 30039916, PMCID: PMC8031136, DOI: 10.1111/jch.13358.Peer-Reviewed Original ResearchConceptsAortic augmentation indexArterial stiffnessUncontrolled hypertensionCarotid-femoral pulse wave velocityHigher aortic augmentation indexCf-PWV levelsCf-PWV valuesBlood pressure levelsPulse wave velocityCross-sectional analysisElderly patientsAugmentation indexBP levelsCf-PWVEntire cohortNormotensionHypertensionOlder individualsOlder populationPatientsTonometry dataCore measuresCohortPressure levelsIndividuals
2016
Assessment of Hypertension in Chronic Kidney Disease
Peixoto A. Assessment of Hypertension in Chronic Kidney Disease. 2016, 15-33. DOI: 10.1007/978-1-4939-6436-9_2.Peer-Reviewed Original ResearchChronic kidney diseaseKidney diseaseHypertensive patientsAccurate blood pressure measurementHypertension-related outcomesAmbulatory BP monitoringOffice BP measurementsClinical trial evidenceAssessment of hypertensionDiagnosis of hypertensionBlood pressure measurementsAmbulatory BPBP monitoringTrial evidenceOffice readingsBP measurementsUse of homePatientsHypertensionDiseasePreferred methodPressure measurementsDiagnosis
2015
Managing Blood Pressure in the Elderly: What Is Different?
Santos S, Pazhayattil G, Peixoto A. Managing Blood Pressure in the Elderly: What Is Different? 2015, 67-83. DOI: 10.1007/978-1-4939-3320-4_7.Peer-Reviewed Original ResearchEnd-stage kidney diseaseManagement of BPMaintenance dialysisCommon cardiovascular risk factorsChronic maintenance dialysisCardiovascular risk factorsBlood pressure managementTreatment of hypertensionElderly patientsBlood pressureDialysis patientsKidney diseaseRisk factorsPatientsAge groupsPressure managementAging processHypertensionDialysisManagementDiseaseElderlyChapter 38 Approach to the Patient with Hypertensive Nephrosclerosis
Peixoto A, Bakris G. Chapter 38 Approach to the Patient with Hypertensive Nephrosclerosis. 2015, 455-469. DOI: 10.1016/b978-0-12-411602-3.00038-x.Peer-Reviewed Original ResearchHypertensive nephrosclerosisEnd-stage renal diseaseNon-malignant hypertensionBlood pressure controlChronic kidney diseaseRenin-angiotensin systemMechanism of injuryArteriolar myogenic responseTuft collapseBase therapyImpaired autoregulationUnderlying diseaseRenal diseaseInterstitial fibrosisKidney diseaseGlomerular hypertensionUrine sedimentMyogenic responsePressure controlGene mutationsDiseaseNephrosclerosisHypertensionPatientsProteinuria
2007
Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
Santos S, Peixoto A. Ambulatory Blood Pressure in Patients With Chronic Kidney Disease. Clinical Hypertension And Vascular Diseases 2007, 389-410. DOI: 10.1007/978-1-59259-978-3_16.Peer-Reviewed Original ResearchChronic kidney diseaseEnd-stage renal diseaseKidney diseaseCases of CKDAmbulatory blood pressureSetting of diabetesAdult US populationHealth care resourcesHealth care problemIncidence of adultESRD patientsBlood pressureRenal diseaseCurrent prevalenceCare resourcesUS populationCare problemsPrevalenceDiseaseHypertensionPatientsSignificant rateMorbidityDiabetesMortality
2000
C037: Reproducibility of ambulatory blood pressure in hemodialysis patients
Peixoto A, Santos S, Mendes R, Crowley S, Orias M, Maldonado R, Mansoor G, White W. C037: Reproducibility of ambulatory blood pressure in hemodialysis patients. American Journal Of Hypertension 2000, 13: 223a-223a. DOI: 10.1016/s0895-7061(00)00757-3.Peer-Reviewed Original Research