Simplified sewerage to prevent urban leptospirosis transmission: a cluster non-randomised controlled trial protocol in disadvantaged urban communities of Salvador, Brazil
Cremonese C, Souza F, Palma F, Sodré J, Brito R, dos Santos Ribeiro P, Santana J, Coelho R, Ticona J, Nazaré R, de Oliveira D, Silva C, Eyre M, de Araújo Mendes V, Knee J, Ristow P, Stauber C, López Y, Giorgi E, Diggle P, Reis M, Cumming O, Ko A, Costa F. Simplified sewerage to prevent urban leptospirosis transmission: a cluster non-randomised controlled trial protocol in disadvantaged urban communities of Salvador, Brazil. BMJ Open 2023, 13: e065009. PMID: 37355266, PMCID: PMC10314607, DOI: 10.1136/bmjopen-2022-065009.Peer-Reviewed Original ResearchConceptsBrazilian Clinical Trials RegistryNon-randomised interventionClinical Trials RegistryNational Research Ethics CommitteeMajor health problemQuasi-experimental study designIntervention-control pairsRoute of exposureSecondary outcomesPrimary outcomeTrials RegistryResearch Ethics CommitteeRisk of exposureSerological measurementsStudy protocolTrial protocolPeer-reviewed publicationsHealth problemsControl clustersAetiological agentInfected rodentsStudy designLeptospirosis transmissionEthics CommitteeUrban slums