Molecular identity of arteries, veins, and lymphatics
Wolf K, Hu H, Isaji T, Dardik A. Molecular identity of arteries, veins, and lymphatics. Journal Of Vascular Surgery 2018, 69: 253-262. PMID: 30154011, PMCID: PMC6309638, DOI: 10.1016/j.jvs.2018.06.195.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsArteriesBiomarkersCOUP Transcription Factor IIEphrin-B2Gene Expression Regulation, DevelopmentalGestational AgeHomeodomain ProteinsHumansIntracellular Signaling Peptides and ProteinsLymphangiogenesisLymphatic VesselsMembrane ProteinsNeovascularization, PhysiologicReceptor, EphB4Receptors, NotchSignal TransductionTumor Suppressor ProteinsVascular Endothelial Growth Factor Receptor-2Vascular Surgical ProceduresVeinsConceptsMolecular identityEphrin-B2 expressionVessel identityVascular identityMolecular determinantsVenous identityArterial-venous identityCritical molecular determinantsEph-B4Specific molecular markersEmbryonic developmentMolecular mechanismsMolecular markersArterial identityUndifferentiated cellsEphrin-B2Adult vesselsDifferent functionsPostsurgical environmentExpressionEndothelial cellsStructural differencesCellsNew therapeutic approachesLymphatic vessels