Abstract 1130: Tenascin-C In Arteriovenous Fistula Failure: Unraveling Venous Remodeling Dynamics
Gonzalez L, Zhang W, Ohashi Y, Vazquez-Padron R, Dardik A. Abstract 1130: Tenascin-C In Arteriovenous Fistula Failure: Unraveling Venous Remodeling Dynamics. Arteriosclerosis Thrombosis And Vascular Biology 2024, 44 DOI: 10.1161/atvb.44.suppl_1.1130.Peer-Reviewed Original ResearchHuman dermal microvascular endothelial cellsInferior vena cavaThrombomodulin expressionTNC expressionPost-AVF creationWild-type C57BL/6 miceMale wild-type C57BL/6 miceOne-year patency rateDecreased thrombomodulin expressionIncreased thrombomodulin expressionArteriovenous fistula failureTenascin-CSites of tissue injuryTranslational therapeutic strategiesDermal microvascular endothelial cellsNF-kB expressionMicrovascular endothelial cellsAVF patencyVena cavaAVF creationSham surgeryC57BL/6 miceFistula failureAVF failureSuperior patency