Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Nishibe T, Kondo Y, Muto A, Dardik A, Ohara Y, Kainuma M, Takeda K. Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. The Journal Of Cardiovascular Surgery 2008, 49: 627-31. PMID: 18670380.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalysis of VarianceAortic Aneurysm, ThoracicAortic DissectionCardiopulmonary BypassChi-Square DistributionFemaleGlycineHumansLeukocyte CountLung DiseasesMalePilot ProjectsPostoperative ComplicationsRespiratory Function TestsSerine Proteinase InhibitorsSulfonamidesTreatment OutcomeConceptsAcute aortic dissectionAortic arch surgeryPostoperative lung dysfunctionSivelestat sodiumAortic dissectionCardiopulmonary bypassWhite blood cellsProtective effectArch surgerySivelestat groupLung dysfunctionControl groupBlood cellsPostoperative lung injuryAortic arch replacementArterial oxygen tensionArch replacementAcute typeLung injuryPulmonary functionCirculatory arrestDeep hypothermiaInflammatory reactionPatientsF ratio