2024
The association between female sex and depression following traumatic brain injury: A systematic review and meta-analysis
Sandhu M, Schonwald A, Boyko M, Jafar T, Freedman I, Woeste J, Kurup A, Funaro M, Zlotnik A, Gruenbaum S, Elsamadicy A, Reynolds R, Gruenbaum B. The association between female sex and depression following traumatic brain injury: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 2024, 168: 105952. PMID: 39603437, DOI: 10.1016/j.neubiorev.2024.105952.Peer-Reviewed Original ResearchPost-TBI depressionTraumatic brain injurySpectrum of TBI severityBrain injuryDiagnosis of depressionNeurobehavioral symptomsTBI severitySystematic reviewDepressionMeta-analysisStatistically significant differenceMedian ageFemale patientsPooled analysisFemale sexRisk factorsSevere casesParticipantsPotential associationSignificant differenceSexSeverityRiskInjurySubjects
2021
Andexanet Alfa Versus 4-Factor Prothrombin Complex Concentrate for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage
Ammar AA, Ammar MA, Owusu KA, Brown SC, Kaddouh F, Elsamadicy AA, Acosta JN, Falcone GJ. Andexanet Alfa Versus 4-Factor Prothrombin Complex Concentrate for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage. Neurocritical Care 2021, 35: 255-261. PMID: 33403588, PMCID: PMC10273779, DOI: 10.1007/s12028-020-01161-5.Peer-Reviewed Original ResearchConceptsFactor Xa inhibitorsSpontaneous intracranial hemorrhageSpontaneous intraparenchymal hemorrhageAndexanet alfaIntracranial hemorrhageProthrombin complex concentrateThrombotic eventsIntraparenchymal hemorrhageFunctional outcomeComplex concentrateXa inhibitorsFour-factor prothrombin complex concentrateOnset of ICHConsecutive adult patientsGood functional outcomeModified Rankin scoreSubgroup of patientsNumber of patientsThromboembolic eventsRankin scoreAdult patientsMedian ageRetrospective reviewHematoma volumeResultsA total