2023
Effects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study
Hengartner A, David W, Reeves B, Craft S, Boroumand S, Clappier M, Hansen J, Fernandez T, Koo A, Tuason D, DiLuna M, Elsamadicy A. Effects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study. Spine Deformity 2023, 11: 1127-1136. PMID: 37093449, DOI: 10.1007/s43390-023-00693-y.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionAdolescent idiopathic scoliosisSpinal fusionPostoperative complicationsRisk factorsIdiopathic scoliosisMultivariate stepwise logistic regressionOral pain medicationTotal hospital lengthTwenty-nine patientsMethodsThe medical recordsSingle institutional studyStepwise logistic regressionMajor academic institutionHospital lengthHospital stayNine patientsPain medicationUnplanned readmissionIntraoperative variablesPatient demographicsPostoperative outcomesRBC transfusionHealthcare utilizationOperative timeAssociation Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Hengartner A, Havlik J, David W, Reeves B, Freedman I, Sarkozy M, Maloy G, Fernandez T, Craft S, Koo A, Tuason D, DiLuna M, Elsamadicy A. Association Between Intravenous to Oral Opioid Transition Time and Length of Hospital Stay After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. The International Journal Of Spine Surgery 2023, 17: 468-476. PMID: 37076256, PMCID: PMC10312154, DOI: 10.14444/8448.Peer-Reviewed Original ResearchPosterior spinal fusionAdolescent idiopathic scoliosisExtended LOSSpinal fusionIdiopathic scoliosisMultivariate analysisMultilevel posterior spinal fusionLength of hospitalPostoperative complication rateMajor academic institutionOral opioidsHospital LOSStudy patientsDischarge dispositionHospital lengthPostoperative complicationsPostoperative courseComplication rateIntraoperative variablesLonger LOSPatient demographicsReadmission ratesMedical recordsUnivariate analysisOdds ratio
2020
Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction.
Elsamadicy AA, Adil SM, Charalambous L, Drysdale N, Koo AB, Lee M, Kundishora AJ, Camara-Quintana J, Kolb L, Laurans M, Abbed K, Karikari IO. Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction. Spine 2020, 45: 268-274. PMID: 31996654, DOI: 10.1097/brs.0000000000003260.Peer-Reviewed Original ResearchConceptsIntraoperative blood transfusionComplex spinal fusionAllogenic blood transfusionPostoperative deliriumBlood transfusionSpinal fusionIndependent associationDeformity correctionMultivariate nominal-logistic regression analysisPrimary complex spinal fusionAdult spine deformity patientsAdult deformity correctionBetter overall patient careGreater complication risksRetrospective cohort studySpine deformity patientsOverall patient careNominal logistic regression analysisMajor academic institutionHospital stayCohort studyBlood lossPrimary outcomeComplication riskDeformity patients
2019
Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study
Elsamadicy AA, Charalambous L, Adil SM, Drysdale N, Lee M, Koo AB, Chouairi F, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study. World Neurosurgery 2019, 129: e311-e316. PMID: 31132486, DOI: 10.1016/j.wneu.2019.05.135.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionNarcotic refillsPain scoresSpinal fusionAffective disordersDeformity correctionNarcotic useDeformity patientsAD cohortPatient-reported pain scoresAdult spine deformity patientsAdult deformity correctionPostoperative pain scoresPostoperative complication ratePreoperative narcotic useHigher pain scoresSpinal deformity patientsSpine deformity patientsMajor academic institutionAmbulatory statusComplication ratePatient demographicsPrimary outcomePostoperative perceptionAssociation Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction
Elsamadicy AA, Drysdale N, Adil SM, Charalambous L, Lee M, Koo A, Freedman IG, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Association Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 128: e231-e237. PMID: 31009775, DOI: 10.1016/j.wneu.2019.04.107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone TransplantationDepressionFemaleHumansIntraoperative Neurophysiological MonitoringLaminectomyLength of StayMaleMiddle AgedMobility LimitationNarcoticsOsteotomyPainPain MeasurementPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPreoperative PeriodSpinal DiseasesSpinal FusionConceptsComplex spinal fusionPain scoresPerioperative complication ratePreoperative narcotic useComplication rateSpinal fusionAmbulatory statusNarcotic usePatient demographicsDeformity correctionPatient-reported pain scoresPrimary complex spinal fusionAdult deformity correctionLast pain scoreNon-user cohortsPostoperative pain scoresPostoperative complication rateHigher pain scoresPhysical therapy regimensPrevalence of depressionGreater mean ageUse of narcoticsMajor academic institutionAmbulatory dayPreoperative useReduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction
Elsamadicy AA, Camara-Quintana J, Kundishora AJ, Lee M, Freedman IG, Long A, Qureshi T, Laurans M, Tomak P, Karikari IO. Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 127: e108-e113. PMID: 30876992, DOI: 10.1016/j.wneu.2019.02.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexComorbidityDiabetes MellitusDyslipidemiasElective Surgical ProceduresFemaleHeart DiseasesHumansHypertensionLaminectomyLength of StayMaleMiddle AgedObesityPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesSpinal DiseasesSpinal FusionTreatment OutcomeUnited StatesYoung AdultConceptsPatient-reported pain scoresComplex spinal fusionPain scoresImpact of obesityReadmission ratesSurgical outcomesDeformity correctionSpinal fusionAmbulatory statusPatient demographicsComplication ratePreoperative body mass indexPrimary complex spinal fusionShort-term surgical outcomesAdult deformity correctionInferior surgical outcomesPostoperative complication profileLength of surgeryPostoperative complication ratePrevalence of obesityBody mass indexPatient-reported outcomesComplex spinal surgeryPaucity of dataMajor academic institutionIntraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction
Elsamadicy AA, Charalambous LT, Sergesketter AR, Drysdale N, Adil SM, Freedman IG, Williamson T, Kundishora AJ, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Intraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction. Journal Of Spine Surgery 2019, 5: 79-87. PMID: 31032442, PMCID: PMC6465460, DOI: 10.21037/jss.2018.12.10.Peer-Reviewed Original ResearchPost-operative deliriumMultivariate nominal-logistic regression analysisComplex spinal fusionIntraoperative ketamine administrationIntraoperative ketamineNominal logistic regression analysisSpinal fusionPatient demographicsKetamine administrationDeformity correctionPrimary complex spinal fusionPost-operative complication rateAdult spine deformity patientsAdult deformity correctionBetter overall patient carePostoperative complication profileProportion of patientsLength of surgeryPost-operative painPost-operative outcomesSpine deformity patientsComplex spinal surgeryOverall patient careRegression analysisMajor academic institutionRate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2018
Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complication Rates, Ambulation, and Length of Hospital Stay After Elective Spinal Fusion (≥3 Levels) in Elderly Spine Deformity Patients
Elsamadicy AA, Sergesketter AR, Kemeny H, Adogwa O, Tarnasky A, Charalambous L, Lubkin DET, Davison MA, Cheng J, Bagley CA, Karikari IO. Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complication Rates, Ambulation, and Length of Hospital Stay After Elective Spinal Fusion (≥3 Levels) in Elderly Spine Deformity Patients. World Neurosurgery 2018, 116: e1122-e1128. PMID: 29870850, DOI: 10.1016/j.wneu.2018.05.185.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseElective spinal fusionPostoperative complication rateObstructive pulmonary diseaseSpine deformity patientsHospital stayCOPD cohortComplication rateSpinal fusionDeformity patientsPulmonary diseaseIncidence of durotomyModifiable risk factorsProportion of smokersLength of staySpinal deformity patientsHealth care resourcesHigh rateMajor academic institutionPostoperative feverPostoperative pneumoniaAmbulatory statusHospital lengthPostoperative complicationsElderly patientsPost-operative drain use in patients undergoing decompression and fusion: incidence of complications and symptomatic hematoma
Adogwa O, Elsamadicy AA, Sergesketter AR, Shammas RL, Vatsia S, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. Post-operative drain use in patients undergoing decompression and fusion: incidence of complications and symptomatic hematoma. Journal Of Spine Surgery 2018, 4: 220-226. PMID: 30069510, PMCID: PMC6046317, DOI: 10.21037/jss.2018.05.09.Peer-Reviewed Original ResearchSurgical site infectionPost-operative complicationsBody mass indexHematoma formationSpinal decompressionPatient demographicsSubfascial drainsPost-operative complication rateSuperficial surgical site infectionAdult spinal deformity patientsPostoperative complication profilePost-operative drainIncidence of complicationsHospital readmission ratesSpinal deformity patientsMajor academic institutionSymptomatic hematomaHospital stayReadmission ratesComplication rateDrain usePrimary outcomeSite infectionOperative timeUse cohortPreoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity
Elsamadicy AA, Adogwa O, Ongele M, Sergesketter AR, Tarnasky A, Lubkin DET, Drysdale N, Cheng J, Bagley CA, Karikari IO. Preoperative Hemoglobin Level is Associated with Increased Health Care Use After Elective Spinal Fusion (≥3 Levels) in Elderly Male Patients with Spine Deformity. World Neurosurgery 2018, 112: e348-e354. PMID: 29355811, DOI: 10.1016/j.wneu.2018.01.046.Peer-Reviewed Original ResearchConceptsElderly male patientsPreoperative Hgb levelsElective spinal fusionHealth care useHgb levelsSpinal fusionMale patientsPostoperative deliriumHemoglobin levelsCare useMean Hgb levelsNon-wound infectionsPreoperative hemoglobin levelLower hemoglobin levelsLower Hgb levelsQuality of careMajor academic institutionPreoperative HgbHospital stayPreoperative levelsPrimary outcomePreoperative identificationHematoma formationMedical recordsSpine surgery
2017
Institutional Review of Mortality in 5434 Consecutive Neurosurgery Patients: Are We Improving?
Elsamadicy AA, Sergesketter A, Sampson JH, Gottfried ON. Institutional Review of Mortality in 5434 Consecutive Neurosurgery Patients: Are We Improving? Neurosurgery 2017, 83: 1269-1276. PMID: 29300938, DOI: 10.1093/neuros/nyx603.Peer-Reviewed Original ResearchConceptsRisk of mortalityCase mix indexSeverity of illnessPostintervention cohortMortality indexQuality InitiativeNeurosurgical serviceDiagnosis-related group codesPre-intervention cohortQuality improvement interventionsEtiology of mortalityHigher case mix indexMajor academic institutionHospital dischargeInpatient mortalityTrauma admissionsNeurosurgery patientsProcedure typeMortality casesInstitutional reviewImprovement interventionsMortalityCohortNeurosurgery inpatientsObserved mortalityThe Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesComplications and 30-Day readmission rates after craniotomy/craniectomy: A single Institutional study of 243 consecutive patients
Elsamadicy AA, Sergesketter A, Adogwa O, Ongele M, Gottfried ON. Complications and 30-Day readmission rates after craniotomy/craniectomy: A single Institutional study of 243 consecutive patients. Journal Of Clinical Neuroscience 2017, 47: 178-182. PMID: 29031542, DOI: 10.1016/j.jocn.2017.09.021.Peer-Reviewed Original ResearchConceptsSensory/motor deficitsConsecutive patientsUnplanned readmissionReadmission ratesMotor deficitsMental statusPost-operative complication rateCommon presented symptomsHigher health care costsEarly hospital readmissionDays of dischargeCraniotomy/craniectomyHigher readmission ratesMajority of patientsSingle institutional studySkilled nursing facilitiesQuality of careHealth care costsHealth care dollarsMajor academic institutionComplication ratePatient demographicsSD ageCommon indicationHospital readmissionImpact of alcohol use on 30-day complication and readmission rates after elective spinal fusion (≥2 levels) for adult spine deformity: a single institutional study of 1,010 patients
Elsamadicy AA, Adogwa O, Vuong VD, Sergesketter A, Reddy G, Cheng J, Bagley CA, Karikari IO. Impact of alcohol use on 30-day complication and readmission rates after elective spinal fusion (≥2 levels) for adult spine deformity: a single institutional study of 1,010 patients. Journal Of Spine Surgery 2017, 3: 403-410. PMID: 29057350, PMCID: PMC5637196, DOI: 10.21037/jss.2017.08.12.Peer-Reviewed Original ResearchElective spinal fusionReadmission ratesSpinal fusionAlcohol useAdult patientsComplication rateSpinal deformityPostoperative complication profilePreoperative alcohol usePostoperative complication ratePost-operative complicationsSingle institutional studyAdult spine deformitySpinal fusion surgeryHistory of alcoholSignificant differencesMajor academic institutionElective correctionBaseline characteristicsPostoperative complicationsIntraoperative variablesPrimary outcomeComplication profileSurgical outcomesFusion surgeryReduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Vuong VD, Lydon E, Behrens S, Cheng J, Bagley CA, Karikari IO. Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients. World Neurosurgery 2017, 107: 233-238. PMID: 28790002, DOI: 10.1016/j.wneu.2017.07.174.Peer-Reviewed Original ResearchConceptsReadmission ratesSmoking statusComplex spinal fusionSpinal fusionPostoperative complicationsPatient demographicsComplication rateSimilar postoperative complication ratesAdult spinal deformity patientsPostoperative complication rateSingle institutional studyBody mass indexElective spinal fusionPatients' smoking statusAdult spine deformitySpinal deformity patientsComplex spinal surgeryMajor academic institutionHospital stayPostoperative outcomesPrimary outcomeWound drainageMass indexOperative timeDeformity patientsIncreased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study
Elsamadicy AA, Adogwa O, Warwick H, Sergesketter A, Lydon E, Shammas RL, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Increased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study. World Neurosurgery 2017, 102: 370-375. PMID: 28359921, DOI: 10.1016/j.wneu.2017.03.096.Peer-Reviewed Original ResearchConceptsElective spinal fusionSpinal fusionSpinal deformityAdult patientsComplication rateComplication Rates AssociatedAllogeneic blood transfusionPostoperative complication rateSingle institutional studyUrinary tract infectionHigh complication rateIntensive care unitMajor academic institutionPatient demographicsReadmission ratesTract infectionsBlood lossBlood transfusionPrimary outcomeWound drainageCare unitIntraoperative durotomyMedical recordsMental statusInstrumentation failureImpact of surgical approach on complication rates after elective spinal fusion (≥3 levels) for adult spine deformity
Elsamadicy AA, Adogwa O, Behrens S, Sergesketter A, Chen A, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of surgical approach on complication rates after elective spinal fusion (≥3 levels) for adult spine deformity. Journal Of Spine Surgery 2017, 3: 31-37. PMID: 28435915, PMCID: PMC5386906, DOI: 10.21037/jss.2017.03.09.Peer-Reviewed Original ResearchElective spinal fusionAnterior/posterior approachAdult spine deformityPosterior approachSurgical approachSpinal fusionComplication ratePatient demographicsSpine deformityPost-operative complication rateAdult spine deformity patientsPost-operative complicationsHigher operative timeDifferent surgical approachesSpine deformity patientsMajor academic institutionRate of intraHigher EBLBlood transfusionPrimary outcomeIntraoperative durotomyOperative timeDeformity patientsMedical recordsHigh incidenceRisk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients
Elsamadicy AA, Adogwa O, Reddy GB, Sergesketter A, Warwick H, Jones T, Cheng J, Bagley CA, Karikari IO. Risk Factors and Independent Predictors of 30-Day Readmission for Altered Mental Status After Elective Spine Surgery for Spine Deformity: A Single-Institutional Study of 1090 Patients. World Neurosurgery 2017, 101: 270-274. PMID: 28192260, DOI: 10.1016/j.wneu.2017.02.001.Peer-Reviewed Original ResearchConceptsElective spine surgeryPostoperative complication rateIndependent predictorsSpine surgeryComplication rateSpine deformityRisk factorsAMS cohortPatient demographicsMental statusInferior surgical outcomesAltered mental statusMultivariate stepwise regression analysisIntensive care unitMajor academic institutionICU transferAdult patientsIntraoperative variablesPulmonary embolismPrimary outcomeCare unitSurgical outcomesMedical recordsReadmissionPatientsImpact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity
Elsamadicy AA, Adogwa O, Lydon E, Reddy G, Kaakati R, Sergesketter A, Gottfried ON, Karikari IO. Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity. World Neurosurgery 2017, 101: 283-288. PMID: 28192259, DOI: 10.1016/j.wneu.2017.02.002.Peer-Reviewed Original ResearchConceptsComplex spinal fusionIntraoperative monitoringPostoperative complicationsReadmission ratesSpinal fusionAdult patientsSpinal deformityUse of IOMIntensive care unit transferSimilar postoperative complicationsBody mass indexOverall surgical outcomeSpinal cord injuryMajor academic institutionIOM useHospital stayComplication rateNerve injuryPatient demographicsTranscranial motorPrimary outcomeMass indexOperative timeSensorimotor deficitsSmoking status