2021
A Unique Subset: Idiopathic Intracranial Hypertension Presenting as Spontaneous CSF Leak of the Anterior Skull Base
Hong CS, Kundishora AJ, Elsamadicy AA, Vining EM, Manes RP, Omay SB. A Unique Subset: Idiopathic Intracranial Hypertension Presenting as Spontaneous CSF Leak of the Anterior Skull Base. Journal Of Neurological Surgery Part B Skull Base 2021, 83: 105-115. PMID: 35433188, PMCID: PMC9010143, DOI: 10.1055/s-0040-1716898.Peer-Reviewed Original ResearchIdiopathic intracranial hypertensionSpontaneous CSF leaksElevated opening pressureCSF leakCerebrospinal fluidOpening pressureSpontaneous CSF leak repairSingle-institution retrospective reviewSkull baseAverage body mass indexLeak repairNormal opening pressureVenous sinus stenosisPermanent CSF diversionBody mass indexHistory of meningitisUnique clinical presentationSpontaneous cerebrospinal fluidCSF leak repairAnterior skull baseRecurrent CSF leakRefractory symptomsSinus stenosisClinical presentationEmpty sella
2019
Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction
Elsamadicy AA, Camara-Quintana J, Kundishora AJ, Lee M, Freedman IG, Long A, Qureshi T, Laurans M, Tomak P, Karikari IO. Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 127: e108-e113. PMID: 30876992, DOI: 10.1016/j.wneu.2019.02.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexComorbidityDiabetes MellitusDyslipidemiasElective Surgical ProceduresFemaleHeart DiseasesHumansHypertensionLaminectomyLength of StayMaleMiddle AgedObesityPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesSpinal DiseasesSpinal FusionTreatment OutcomeUnited StatesYoung AdultConceptsPatient-reported pain scoresComplex spinal fusionPain scoresImpact of obesityReadmission ratesSurgical outcomesDeformity correctionSpinal fusionAmbulatory statusPatient demographicsComplication ratePreoperative body mass indexPrimary complex spinal fusionShort-term surgical outcomesAdult deformity correctionInferior surgical outcomesPostoperative complication profileLength of surgeryPostoperative complication ratePrevalence of obesityBody mass indexPatient-reported outcomesComplex spinal surgeryPaucity of dataMajor academic institutionRate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2018
Post-operative drain use in patients undergoing decompression and fusion: incidence of complications and symptomatic hematoma
Adogwa O, Elsamadicy AA, Sergesketter AR, Shammas RL, Vatsia S, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. Post-operative drain use in patients undergoing decompression and fusion: incidence of complications and symptomatic hematoma. Journal Of Spine Surgery 2018, 4: 220-226. PMID: 30069510, PMCID: PMC6046317, DOI: 10.21037/jss.2018.05.09.Peer-Reviewed Original ResearchSurgical site infectionPost-operative complicationsBody mass indexHematoma formationSpinal decompressionPatient demographicsSubfascial drainsPost-operative complication rateSuperficial surgical site infectionAdult spinal deformity patientsPostoperative complication profilePost-operative drainIncidence of complicationsHospital readmission ratesSpinal deformity patientsMajor academic institutionSymptomatic hematomaHospital stayReadmission ratesComplication rateDrain usePrimary outcomeSite infectionOperative timeUse cohortMinimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients
Nayar G, Wang T, Sankey EW, Berry-Candelario J, Elsamadicy AA, Back A, Karikari I, Isaacs R. Minimally Invasive Lateral Access Surgery and Reoperation Rates: A Multi-Institution Retrospective Review of 2060 Patients. World Neurosurgery 2018, 116: e744-e749. PMID: 29787875, DOI: 10.1016/j.wneu.2018.05.082.Peer-Reviewed Original ResearchConceptsRate of reoperationLateral access surgeryLumbar spine surgeryMore comorbiditiesSurgical approachSpine surgeryDecompressive lumbar spine surgeryElective lumbar spinal surgeryMulti-institution retrospective reviewAccess surgeryLower body mass indexLumbar spinal surgeryBody mass indexOpen posterior approachHealth care systemOnly significant predictorAdditional readmissionsLT cohortOP cohortOP surgeryReoperation ratePatient demographicsSurgical complicationsRetrospective reviewMass indexDoes Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers?
Adogwa O, Vuong VD, Elsamadicy AA, Lilly DT, Desai SA, Khalid S, Cheng J, Bagley CA. Does Nasal Carriage of Staphylococcus aureus Increase the Risk of Postoperative Infections After Elective Spine Surgery: Do Most Infections Occur in Carriers? World Neurosurgery 2018, 116: e519-e524. PMID: 29772370, DOI: 10.1016/j.wneu.2018.05.025.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgeryWound infectionNasal colonizationSite infectionSpine surgeryCases of SSIPost-operative surgical site infectionDirect medical record reviewAdult spinal deformity surgeryProspective multi-institutional studyLocal vancomycin powderPostoperative wound infectionDeep wound infectionHistory of diabetesMajority of patientsMedical record reviewDay of surgeryBody mass indexStandard deviation agePost-operative infectionSpinal deformity surgeryMulti-institutional studyBaseline characteristicsNasal carriageInfluence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of health
2017
The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesReduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Vuong VD, Lydon E, Behrens S, Cheng J, Bagley CA, Karikari IO. Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients. World Neurosurgery 2017, 107: 233-238. PMID: 28790002, DOI: 10.1016/j.wneu.2017.07.174.Peer-Reviewed Original ResearchConceptsReadmission ratesSmoking statusComplex spinal fusionSpinal fusionPostoperative complicationsPatient demographicsComplication rateSimilar postoperative complication ratesAdult spinal deformity patientsPostoperative complication rateSingle institutional studyBody mass indexElective spinal fusionPatients' smoking statusAdult spine deformitySpinal deformity patientsComplex spinal surgeryMajor academic institutionHospital stayPostoperative outcomesPrimary outcomeWound drainageMass indexOperative timeDeformity patientsProphylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases.
Adogwa O, Elsamadicy AA, Sergesketter A, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. Journal Of Neurosurgery Spine 2017, 27: 328-334. PMID: 28665245, DOI: 10.3171/2017.2.spine161310.Peer-Reviewed Original ResearchConceptsSurgical site infectionMean body mass indexIntraoperative vancomycin powderVancomycin powderWound infectionAdult patientsProphylactic useCases of SSIPatients' mean body mass indexMicrobiological patternDirect medical record reviewPostoperative surgical site infectionDuke University Medical CenterDeep wound infectionEmpirical antibiotic therapyHistory of diabetesAdverse clinical outcomesMedical record reviewConsecutive surgical casesDay of surgeryBody mass indexSpinal deformity surgeryUniversity Medical CenterRandomized control trialHealth care systemImmediate Postoperative Pain Scores Predict Neck Pain Profile up to 1 Year Following Anterior Cervical Discectomy and Fusion
Adogwa O, Elsamadicy AA, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Immediate Postoperative Pain Scores Predict Neck Pain Profile up to 1 Year Following Anterior Cervical Discectomy and Fusion. Global Spine Journal 2017, 8: 231-236. PMID: 29796370, PMCID: PMC5958477, DOI: 10.1177/2192568217706700.Peer-Reviewed Original ResearchImmediate postoperative pain scoresNeck pain scoresPostoperative pain scoresPain scoresAnterior cervical discectomyBody mass indexCervical discectomyPain 12 monthsRetrospective cohort reviewFirst postoperative dayMajor academic medical centerImmediate postoperative patientsAcademic medical centerACDF proceduresIndex surgeryPain ProfileACDF surgeryCohort reviewPostoperative dayIndependent predictorsPain outcomesPostoperative patientsMass indexRetrospective studyMean ageImpact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity
Elsamadicy AA, Adogwa O, Lydon E, Reddy G, Kaakati R, Sergesketter A, Gottfried ON, Karikari IO. Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity. World Neurosurgery 2017, 101: 283-288. PMID: 28192259, DOI: 10.1016/j.wneu.2017.02.002.Peer-Reviewed Original ResearchConceptsComplex spinal fusionIntraoperative monitoringPostoperative complicationsReadmission ratesSpinal fusionAdult patientsSpinal deformityUse of IOMIntensive care unit transferSimilar postoperative complicationsBody mass indexOverall surgical outcomeSpinal cord injuryMajor academic institutionIOM useHospital stayComplication rateNerve injuryPatient demographicsTranscranial motorPrimary outcomeMass indexOperative timeSensorimotor deficitsSmoking statusImpact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures
Sergesketter A, Elsamadicy AA, Gottfried ON. Impact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures. World Neurosurgery 2017, 100: 244-249. PMID: 28093346, DOI: 10.1016/j.wneu.2017.01.019.Peer-Reviewed Original ResearchConceptsImpact of obesityBody mass indexReadmission ratesCranial surgeryPostoperative complicationsMass indexSurgical outcomesPreoperative body mass indexMean body mass indexBaseline patient characteristicsEffect of obesityPrevalence of obesityMajor academic institutionHospital stayMost patientsObese cohortObese patientsPatient characteristicsSurgical complicationsBlood lossConsecutive patientsNonobese cohortPrimary outcomeTumor excisionMedical records
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgeryRacial Disparities in 30-Day Readmission Rates After Elective Spine Surgery
Adogwa O, Elsamadicy AA, Mehta AI, Cheng J, Bagley CA, Karikari IO. Racial Disparities in 30-Day Readmission Rates After Elective Spine Surgery. Spine 2016, 41: 1677-1682. PMID: 27054453, DOI: 10.1097/brs.0000000000001616.Peer-Reviewed Original ResearchConceptsElective spine surgerySpine surgeryReadmission ratesBlack patientsUnplanned readmissionIndependent predictorsWhite patientsOutcome measuresMultivariate logistic regression modelRacial disparitiesCauses of readmissionDays of dischargeRetrospective cohort reviewRisk-adjusted oddsHigher readmission ratesBody mass indexPost-discharge careMain outcome measuresMultivariate logistic regressionMajor academic medical centerAcademic medical centerLogistic regression modelsHospital stayNonsurgical complicationsBaseline characteristicsPatient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery
Elsamadicy AA, Adogwa O, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Patient Body Mass Index is an Independent Predictor of 30-Day Hospital Readmission After Elective Spine Surgery. World Neurosurgery 2016, 96: 148-151. PMID: 27593714, DOI: 10.1016/j.wneu.2016.08.097.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexCase-Control StudiesComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisObesityPatient ReadmissionPneumoniaPostoperative ComplicationsRadiculopathyRisk FactorsSpinal DiseasesSpinal FusionSpinal StenosisSpondylolisthesisSurgical Wound InfectionUrinary Tract InfectionsConceptsElective spine surgeryBody mass indexPreoperative body mass indexMultivariate logistic regression analysisDays of dischargeIndependent risk factorHospital readmissionSpine surgeryLogistic regression analysisPreoperative obesityReadmission ratesIndependent predictorsMass indexRisk factorsEarly unplanned hospital readmissionPatient body mass indexUnplanned hospital readmissionPostoperative complication rateAppropriate risk stratificationPrevalence of obesityMajor academic medical centerAcademic medical centerRegression analysisHealth care climateIndex surgeryRace as an Independent Predictor of Temporal Delay in Time to Diagnosis and Treatment in Patients with Cervical Stenosis: A Study of 133 Patients with Anterior Cervical Discectomy and Fusion
Elsamadicy AA, Adogwa O, Fialkoff J, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Race as an Independent Predictor of Temporal Delay in Time to Diagnosis and Treatment in Patients with Cervical Stenosis: A Study of 133 Patients with Anterior Cervical Discectomy and Fusion. World Neurosurgery 2016, 96: 107-110. PMID: 27567581, DOI: 10.1016/j.wneu.2016.08.070.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnxietyBlack or African AmericanCervical VertebraeDecompression, SurgicalDelayed DiagnosisDepressionDiskectomyEthnicityFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisRetrospective StudiesRisk FactorsSex FactorsSpinal FusionSpinal StenosisTime-to-TreatmentWhite PeopleConceptsAnterior cervical discectomyVisual analog scaleCervical stenosisIndependent predictorsCervical discectomyPatient demographicsMultivariate analysisElective anterior cervical discectomyVAS neck pain scoresPatient-reported outcome measuresSignificant cervical stenosisSymptomatic cervical stenosisVAS neck painIndependent risk factorPostoperative complication rateWorse postoperative outcomesBody mass indexStandard deviation ageMajor academic medical centerHistory of depressionAcademic medical centerPreoperative painNeurological sequelaePain scoresPostoperative outcomesAssociation Between Baseline Affective Disorders and 30-Day Readmission Rates in Patients Undergoing Elective Spine Surgery
Adogwa O, Elsamadicy AA, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Association Between Baseline Affective Disorders and 30-Day Readmission Rates in Patients Undergoing Elective Spine Surgery. World Neurosurgery 2016, 94: 432-436. PMID: 27450978, DOI: 10.1016/j.wneu.2016.07.045.Peer-Reviewed Original ResearchConceptsElective spine surgeryDays of dischargeSpine surgeryReadmission ratesPsychiatric comorbidityAffective disordersCause readmissionMultivariate logistic regression modelPatient-reported outcome measuresPatient-reported outcome dataRate of readmissionBody mass indexMajor academic medical centerAcademic medical centerLogistic regression modelsUnplanned readmissionBaseline characteristicsEarly readmissionPatient ageIndependent predictorsPrimary outcomeMass indexPsychologic disordersMedical recordsUnivariate analysis