2021
Characteristics and Outcomes of Elderly Patients With Hypertrophic Cardiomyopathy
Alashi A, Smedira NG, Popovic ZB, Fava A, Thamilarasan M, Kapadia SR, Wierup P, Lever HM, Desai MY. Characteristics and Outcomes of Elderly Patients With Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2021, 10: e018527. PMID: 33506683, PMCID: PMC7955450, DOI: 10.1161/jaha.120.018527.Peer-Reviewed Original ResearchConceptsLeft ventricular outflow tract gradientVentricular outflow tract gradientOutflow tract gradientElderly patientsHypertrophic cardiomyopathyTract gradientObstructive subgroupRisk factorsDynamic left ventricular outflow tract obstructionSudden cardiac death risk factorsLeft ventricular outflow tract obstructionAppropriate internal defibrillator dischargeVentricular outflow tract obstructionBasal septal thicknessConclusion Elderly patientsDeath risk factorsSeptal reduction therapyThoracic Surgeons scoreConsecutive elderly patientsOutflow tract obstructionVentricular mass indexBasal septal hypertrophyLong-term outcomesHospital deathTract obstruction
2020
Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy
Alashi A, Smedira NG, Hodges K, Popovic ZB, Thamilarasan M, Wierup P, Lever HM, Desai MY. Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy. Journal Of The American Heart Association 2020, 10: e016210. PMID: 33342243, PMCID: PMC7955478, DOI: 10.1161/jaha.120.016210.Peer-Reviewed Original ResearchMeSH KeywordsCardiac Surgical ProceduresCardiomyopathy, HypertrophicDissectionEarly Medical InterventionEchocardiography, StressExercise TestFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePatient SelectionPractice Guidelines as TopicSeverity of Illness IndexSurvival AnalysisUnited StatesConceptsVentricular outflow tract gradientObstructive coronary artery diseaseBetter long-term survivalSurgical myectomyOutflow tract gradientObstructive hypertrophic cardiomyopathyCoronary artery diseaseLong-term survivalClass ITract gradientEarly surgeryArtery diseaseHypertrophic cardiomyopathyLeft ventricular outflow tract gradientAppropriate internal defibrillator dischargePrimary composite end pointBasal septal thicknessClass I indicationsPrimary composite eventsHypertrophic obstructive cardiomyopathyComposite end pointLong-term outcomesComposite eventsEarly referralObstructive cardiomyopathy
2019
Dilation of the Proximal Thoracic Aorta in an Asymptomatic Primary Prevention Population Undergoing Noncontrast Chest Computed Tomography
Alashi A, Lang R, Seballos R, Feinleib S, Sukol R, Roselli EE, Svensson LG, Kalahasti V, Schoenhagen P, Flamm SD, Griffin BP, Desai MY. Dilation of the Proximal Thoracic Aorta in an Asymptomatic Primary Prevention Population Undergoing Noncontrast Chest Computed Tomography. Circulation 2019, 139: 557-558. PMID: 30586688, DOI: 10.1161/circulationaha.118.036191.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortographyAsymptomatic DiseasesComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseDilatation, PathologicEarly DiagnosisHumansIncidental FindingsMaleMiddle AgedPredictive Value of TestsPrimary PreventionUnited StatesVascular CalcificationConceptsAortic aneurysmDissection/rupturePrimary prevention populationCoronary artery calciumProximal thoracic aortaThoracic aortic aneurysmNoncontrast chestPrevention populationArtery calciumThoracic aortaSurgical techniqueSudden deathProximal ascendingTrue prevalenceImproved surveillanceAneurysmsEarly detectionDevastating diseaseDeathAortaChestMortalityPrevalenceDiseaseExsanguination