2020
Impact of Temporal Changes in Left Ventricular Systolic Function on Outcomes in Takotsubo Cardiomyopathy
Isaza N, Alashi A, Faulx J, Popovic ZB, Menon V, Ellis SG, Faulx M, Kapadia SR, Griffin BP, Desai MY. Impact of Temporal Changes in Left Ventricular Systolic Function on Outcomes in Takotsubo Cardiomyopathy. JACC Cardiovascular Imaging 2020, 14: 1273-1274. PMID: 33341418, DOI: 10.1016/j.jcmg.2020.10.021.Peer-Reviewed Original ResearchMeSH KeywordsHumansPredictive Value of TestsSystoleTakotsubo CardiomyopathyVentricular Function, LeftLV Global Function Index Provides Incremental Prognostic Value Over LGE and LV GLS in HCM
Desai MY, Mentias A, Alashi A, Flamm SD, Thamilarasan M, Lever HM, Popovic ZB. LV Global Function Index Provides Incremental Prognostic Value Over LGE and LV GLS in HCM. JACC Cardiovascular Imaging 2020, 13: 2052-2054. PMID: 32563635, DOI: 10.1016/j.jcmg.2020.03.023.Peer-Reviewed Original ResearchCardiomyopathy, HypertrophicHumansPredictive Value of TestsPrognosisStroke VolumeVentricular Function, Left
2019
Long-Term Outcomes After Aortic Valve Surgery in Patients With Asymptomatic Chronic Aortic Regurgitation and Preserved LVEF Impact of Baseline and Follow-Up Global Longitudinal Strain
Alashi A, Khullar T, Mentias A, Gillinov AM, Roselli EE, Svensson LG, Popovic ZB, Griffin BP, Desai MY. Long-Term Outcomes After Aortic Valve Surgery in Patients With Asymptomatic Chronic Aortic Regurgitation and Preserved LVEF Impact of Baseline and Follow-Up Global Longitudinal Strain. JACC Cardiovascular Imaging 2019, 13: 12-21. PMID: 30772216, DOI: 10.1016/j.jcmg.2018.12.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic ValveAortic Valve InsufficiencyAsymptomatic DiseasesChronic DiseaseEchocardiographyFemaleHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeVentricular Function, LeftConceptsLeft ventricular ejection fractionLV-GLS valuesChronic aortic regurgitationAortic valve surgeryAortic regurgitationGlobal longitudinal strainAV surgeryLV-GLSValve surgeryMean left ventricular ejection fractionAsymptomatic chronic aortic regurgitationChronic severe aortic regurgitationVentricular global longitudinal strainBetter long-term survivalHigher long-term mortalityLongitudinal strainPost-operative echocardiographySevere aortic regurgitationLong-term mortalityVentricular ejection fractionSubgroup of patientsLong-term survivalSubgroup of subjectsAV replacementBaseline echocardiographyDilation of the Proximal Thoracic Aorta in an Asymptomatic Primary Prevention Population Undergoing Noncontrast Chest Computed Tomography
Alashi A, Lang R, Seballos R, Feinleib S, Sukol R, Roselli EE, Svensson LG, Kalahasti V, Schoenhagen P, Flamm SD, Griffin BP, Desai MY. Dilation of the Proximal Thoracic Aorta in an Asymptomatic Primary Prevention Population Undergoing Noncontrast Chest Computed Tomography. Circulation 2019, 139: 557-558. PMID: 30586688, DOI: 10.1161/circulationaha.118.036191.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortographyAsymptomatic DiseasesComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseDilatation, PathologicEarly DiagnosisHumansIncidental FindingsMaleMiddle AgedPredictive Value of TestsPrimary PreventionUnited StatesVascular CalcificationConceptsAortic aneurysmDissection/rupturePrimary prevention populationCoronary artery calciumProximal thoracic aortaThoracic aortic aneurysmNoncontrast chestPrevention populationArtery calciumThoracic aortaSurgical techniqueSudden deathProximal ascendingTrue prevalenceImproved surveillanceAneurysmsEarly detectionDevastating diseaseDeathAortaChestMortalityPrevalenceDiseaseExsanguination
2018
Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data
Oikonomou EK, Marwan M, Desai MY, Mancio J, Alashi A, Centeno E, Thomas S, Herdman L, Kotanidis CP, Thomas KE, Griffin BP, Flamm SD, Antonopoulos AS, Shirodaria C, Sabharwal N, Deanfield J, Neubauer S, Hopewell JC, Channon KM, Achenbach S, Antoniades C. Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. The Lancet 2018, 392: 929-939. PMID: 30170852, PMCID: PMC6137540, DOI: 10.1016/s0140-6736(18)31114-0.Peer-Reviewed Original ResearchMeSH KeywordsAdipocytesAdipose TissueAdolescentAdultAgedAged, 80 and overComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary VesselsFemaleFollow-Up StudiesHumansImaging, Three-DimensionalMaleMiddle AgedPlaque, AtheroscleroticPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentSurvival AnalysisYoung AdultConceptsRight coronary arteryProximal right coronary arteryCardiac mortalityCoronary inflammationCoronary CTACoronary arteryDerivation cohortValidation cohortOutcome dataHealth Research Oxford Biomedical Research CentreCoronary artery disease indexHigh-risk plaque featuresPerivascular fat attenuation indexCoronary artery inflammationFat attenuation indexIntensive secondary preventionCardiovascular risk factorsResidual cardiovascular riskProspective outcome dataMajor coronary arteriesHounsfield unitsLeft circumflex arteryCox regression modelRisk predictionCardiac risk prediction
2017
Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction
Alashi A, Mentias A, Abdallah A, Feng K, Gillinov AM, Rodriguez LL, Johnston DR, Svensson LG, Popovic ZB, Griffin BP, Desai MY. Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction. JACC Cardiovascular Imaging 2017, 11: 673-682. PMID: 28624411, DOI: 10.1016/j.jcmg.2017.02.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic Valve InsufficiencyAsymptomatic DiseasesBiomechanical PhenomenaChronic DiseaseDisease ProgressionEchocardiography, Doppler, ColorFemaleHumansMaleMiddle AgedMyocardial ContractionPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular ejection fractionAortic valve surgeryChronic aortic regurgitationLong-term mortalityGlobal longitudinal strainRight ventricular systolic pressureVentricular global longitudinal strainLV end-systolic dimensionLV-GLSVentricular systolic pressureEnd-systolic dimensionVentricular ejection fractionAortic regurgitationAsymptomatic patientsTerm mortalityValve surgerySTS scoreEjection fractionSystolic pressurePrognostic utilityLeft ventricular global longitudinal strainMultivariable Cox survival analysisSevere chronic aortic regurgitationLongitudinal strainMean STS scoreAortic Cross-Sectional Area/Height Ratio and Outcomes in Patients With Bicuspid Aortic Valve and a Dilated Ascending Aorta
Masri A, Kalahasti V, Svensson LG, Alashi A, Schoenhagen P, Roselli EE, Johnston DR, Rodriguez LL, Griffin BP, Desai MY. Aortic Cross-Sectional Area/Height Ratio and Outcomes in Patients With Bicuspid Aortic Valve and a Dilated Ascending Aorta. Circulation Cardiovascular Imaging 2017, 10: e006249. PMID: 28592593, DOI: 10.1161/circimaging.116.006249.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnatomic LandmarksAortaAortic AneurysmAortic ValveAortographyBicuspid Aortic Valve DiseaseCause of DeathChi-Square DistributionComputed Tomography AngiographyDilatation, PathologicFemaleHeart Valve DiseasesHospital MortalityHumansKaplan-Meier EstimateMagnetic Resonance AngiographyMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisOhioPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsBicuspid aortic valve patientsProximal ascending aortaAortic valve patientsBicuspid aortic valveAortic areaCardiovascular deathAscending aortaAortic surgeryValve patientsAortic valveMultivariable Cox survival analysisRight ventricular systolic pressureLong-term cardiovascular mortalityContrast-enhanced thoracicThoracic Surgeons scoreSevere aortic stenosisVentricular systolic pressureCox survival analysisMagnetic resonance angiographyHeight ratioAortic regurgitationCardiovascular mortalitySurgeons scoreAortic stenosisImproved survival
2016
Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Primary Mitral Regurgitation and Preserved Systolic Function Undergoing Mitral Valve Surgery
Alashi A, Mentias A, Patel K, Gillinov AM, Sabik JF, Popović ZB, Mihaljevic T, Suri RM, Rodriguez LL, Svensson LG, Griffin BP, Desai MY. Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Primary Mitral Regurgitation and Preserved Systolic Function Undergoing Mitral Valve Surgery. Circulation Cardiovascular Imaging 2016, 9: e004451. PMID: 27342145, DOI: 10.1161/circimaging.115.004451.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsymptomatic DiseasesBiomarkersCardiac Surgical ProceduresChi-Square DistributionEchocardiographyFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMultivariate AnalysisMyocardial ContractionNatriuretic Peptide, BrainPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeVentricular Function, LeftVentricular Function, RightVentricular PressureConceptsLeft ventricular ejection fractionMitral valve surgeryVentricular ejection fractionLog-transformed BNPThoracic Surgeons scoreBrain natriuretic peptidePrimary mitral regurgitationRight ventricular systolic pressureSignificant primary mitral regurgitationVentricular systolic pressureGlobal longitudinal strainIncremental prognostic utilityLV-GLSAsymptomatic patientsValve surgeryEjection fractionMitral regurgitationSurgeons scoreNatriuretic peptideSystolic pressurePrognostic utilityBaseline LV global longitudinal strainBaseline right ventricular systolic pressureMitral effective regurgitant orificeLV global longitudinal strain