2020
Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy
Alashi A, Smedira NG, Hodges K, Popovic ZB, Thamilarasan M, Wierup P, Lever HM, Desai MY. Outcomes in Guideline‐Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy. Journal Of The American Heart Association 2020, 10: e016210. PMID: 33342243, PMCID: PMC7955478, DOI: 10.1161/jaha.120.016210.Peer-Reviewed Original ResearchMeSH KeywordsCardiac Surgical ProceduresCardiomyopathy, HypertrophicDissectionEarly Medical InterventionEchocardiography, StressExercise TestFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePatient SelectionPractice Guidelines as TopicSeverity of Illness IndexSurvival AnalysisUnited StatesConceptsVentricular outflow tract gradientObstructive coronary artery diseaseBetter long-term survivalSurgical myectomyOutflow tract gradientObstructive hypertrophic cardiomyopathyCoronary artery diseaseLong-term survivalClass ITract gradientEarly surgeryArtery diseaseHypertrophic cardiomyopathyLeft ventricular outflow tract gradientAppropriate internal defibrillator dischargePrimary composite end pointBasal septal thicknessClass I indicationsPrimary composite eventsHypertrophic obstructive cardiomyopathyComposite end pointLong-term outcomesComposite eventsEarly referralObstructive cardiomyopathyCharacteristics and Outcomes of Patients With Takotsubo Syndrome: Incremental Prognostic Value of Baseline Left Ventricular Systolic Function
Alashi A, Isaza N, Faulx J, Popovic ZB, Menon V, Ellis SG, Faulx M, Kapadia SR, Griffin BP, Desai MY. Characteristics and Outcomes of Patients With Takotsubo Syndrome: Incremental Prognostic Value of Baseline Left Ventricular Systolic Function. Journal Of The American Heart Association 2020, 9: e016537. PMID: 32755253, PMCID: PMC7660826, DOI: 10.1161/jaha.120.016537.Peer-Reviewed Original ResearchConceptsBaseline LV ejection fractionLV ejection fractionIncremental prognostic valueLV-GLSTakotsubo syndromePrognostic valueLower baseline LV ejection fractionObstructive coronary artery diseaseVentricular global longitudinal strainMultivariate Cox survival analysisMean LV ejection fractionWorse LV-GLSOutcomes of patientsPrimary end pointVentricular systolic functionCoronary artery diseaseGlobal longitudinal strainLong-term outcomesCox survival analysisPhysical triggersPrognostic cutoffCause mortalityApical ballooningConclusions PatientsSystolic function
2019
P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy
Isaza N, Alashi A, Faulx J, Popovic Z, Menon V, Faulx M, Griffin B, Desai M. P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy. European Heart Journal 2019, 40: ehz748.0698. DOI: 10.1093/eurheartj/ehz748.0698.Peer-Reviewed Original ResearchLV ejection fractionLong-term mortalityLV-GLSGlobal longitudinal strainTransthoracic echocardiographyFunctional recoveryLV global longitudinal strainMultivariable Cox survival analysisLarge single-center studyObstructive coronary artery diseaseVentricular global longitudinal strainHigher long-term mortalityLongitudinal strainMean troponin ISingle-center studyCoronary artery diseaseKaplan-Meier curvesCox survival analysisMajority of casesAnginal symptomsPrimary endpointAngiographic evaluationApical ballooningArtery diseaseEjection fraction