2019
P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy
Isaza N, Alashi A, Faulx J, Popovic Z, Menon V, Faulx M, Griffin B, Desai M. P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy. European Heart Journal 2019, 40: ehz748.0698. DOI: 10.1093/eurheartj/ehz748.0698.Peer-Reviewed Original ResearchLV ejection fractionLong-term mortalityLV-GLSGlobal longitudinal strainTransthoracic echocardiographyFunctional recoveryLV global longitudinal strainMultivariable Cox survival analysisLarge single-center studyObstructive coronary artery diseaseVentricular global longitudinal strainHigher long-term mortalityLongitudinal strainMean troponin ISingle-center studyCoronary artery diseaseKaplan-Meier curvesCox survival analysisMajority of casesAnginal symptomsPrimary endpointAngiographic evaluationApical ballooningArtery diseaseEjection fractionLong-Term Outcomes After Aortic Valve Surgery in Patients With Asymptomatic Chronic Aortic Regurgitation and Preserved LVEF Impact of Baseline and Follow-Up Global Longitudinal Strain
Alashi A, Khullar T, Mentias A, Gillinov AM, Roselli EE, Svensson LG, Popovic ZB, Griffin BP, Desai MY. Long-Term Outcomes After Aortic Valve Surgery in Patients With Asymptomatic Chronic Aortic Regurgitation and Preserved LVEF Impact of Baseline and Follow-Up Global Longitudinal Strain. JACC Cardiovascular Imaging 2019, 13: 12-21. PMID: 30772216, DOI: 10.1016/j.jcmg.2018.12.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic ValveAortic Valve InsufficiencyAsymptomatic DiseasesChronic DiseaseEchocardiographyFemaleHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeVentricular Function, LeftConceptsLeft ventricular ejection fractionLV-GLS valuesChronic aortic regurgitationAortic valve surgeryAortic regurgitationGlobal longitudinal strainAV surgeryLV-GLSValve surgeryMean left ventricular ejection fractionAsymptomatic chronic aortic regurgitationChronic severe aortic regurgitationVentricular global longitudinal strainBetter long-term survivalHigher long-term mortalityLongitudinal strainPost-operative echocardiographySevere aortic regurgitationLong-term mortalityVentricular ejection fractionSubgroup of patientsLong-term survivalSubgroup of subjectsAV replacementBaseline echocardiography
2018
Characteristics and longer-term outcomes of paravalvular leak after aortic and mitral valve surgery
Shah S, Alashi A, Pettersson GB, Rodriguez LL, Gillinov AM, Grimm RA, Navia J, Kapadia SR, Svensson LG, Griffin BP, Desai MY. Characteristics and longer-term outcomes of paravalvular leak after aortic and mitral valve surgery. Journal Of Thoracic And Cardiovascular Surgery 2018, 157: 1785-1792.e1. PMID: 30414770, DOI: 10.1016/j.jtcvs.2018.08.096.Peer-Reviewed Original ResearchConceptsReoperative cardiac surgeryLong-term mortalityRight ventricular systolic pressureGreater paravalvular leakMitral valve surgeryVentricular systolic pressureParavalvular leakLong-term outcomesLong-term survivalSTS scoreMV surgeryValve surgeryInfectious etiologySystolic pressureMultivariable Cox survival analysisGreater long-term mortalityAortic paravalvular leakMean STS scoreThoracic Surgeons scoreMild paravalvular leakVentricular ejection fractionCox survival analysisExcellent perioperative outcomesPerioperative outcomesPrimary endpointRate of Progression of Aortic Stenosis and its Impact on Outcomes in Patients With Radiation-Associated Cardiac Disease A Matched Cohort Study
Donnellan E, Griffin BP, Johnston DR, Popovic ZB, Alashi A, Kapadia SR, Tuzcu EM, Krishnaswamy A, Mick S, Svensson LG, Desai MY. Rate of Progression of Aortic Stenosis and its Impact on Outcomes in Patients With Radiation-Associated Cardiac Disease A Matched Cohort Study. JACC Cardiovascular Imaging 2018, 11: 1072-1080. PMID: 29909108, DOI: 10.1016/j.jcmg.2018.04.019.Peer-Reviewed Original ResearchConceptsAortic valve replacementLong-term mortalityModerate aortic stenosisAortic stenosisRate of progressionPrior XRTLong-term survivalXRT groupHigher long-term mortalityAortic valve gradientMatched Cohort StudyComparison groupBasis of ageMediastinal radiotherapyCause mortalityValve gradientCohort studyValve replacementMore patientsXRT patientsPatientsHigh mortalityMortalityPrior exposureProgression
2017
Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction
Alashi A, Mentias A, Abdallah A, Feng K, Gillinov AM, Rodriguez LL, Johnston DR, Svensson LG, Popovic ZB, Griffin BP, Desai MY. Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction. JACC Cardiovascular Imaging 2017, 11: 673-682. PMID: 28624411, DOI: 10.1016/j.jcmg.2017.02.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic Valve InsufficiencyAsymptomatic DiseasesBiomechanical PhenomenaChronic DiseaseDisease ProgressionEchocardiography, Doppler, ColorFemaleHumansMaleMiddle AgedMyocardial ContractionPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular ejection fractionAortic valve surgeryChronic aortic regurgitationLong-term mortalityGlobal longitudinal strainRight ventricular systolic pressureVentricular global longitudinal strainLV end-systolic dimensionLV-GLSVentricular systolic pressureEnd-systolic dimensionVentricular ejection fractionAortic regurgitationAsymptomatic patientsTerm mortalityValve surgerySTS scoreEjection fractionSystolic pressurePrognostic utilityLeft ventricular global longitudinal strainMultivariable Cox survival analysisSevere chronic aortic regurgitationLongitudinal strainMean STS score