2021
Predictive value of NT-proBNP in non-obstructive hypertrophic cardiomyopathy
Hutt E, Mentias A, Alashi A, Fava A, Popovic Z, Thamilarasan M, Lever H, Desai M. Predictive value of NT-proBNP in non-obstructive hypertrophic cardiomyopathy. European Heart Journal 2021, 42: ehab724.0765. DOI: 10.1093/eurheartj/ehab724.0765.Peer-Reviewed Original ResearchNT-proBNP ratioLV ejection fractionSerum NT-proBNPNT-proBNPAsymptomatic patientsPrimary endpointSeptal myectomySudden cardiac death risk factorsNon-obstructive hypertrophic cardiomyopathyKaplan-Meier survival analysisDeath risk factorsEarly disease stagesHypertrophic cardiomyopathy patientsImplantable defibrillator dischargesEjection fractionHeart transplantPrimary outcomeRisk stratificationPrognostic valueAdverse outcomesDisease stageCardiomyopathy patientsRisk factorsEcho variablesHypertrophic cardiomyopathy
2019
P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy
Isaza N, Alashi A, Faulx J, Popovic Z, Menon V, Faulx M, Griffin B, Desai M. P1951Serial left ventricular global longitudinal strain and mortality in patients with Takotsubo cardiomyopathy. European Heart Journal 2019, 40: ehz748.0698. DOI: 10.1093/eurheartj/ehz748.0698.Peer-Reviewed Original ResearchLV ejection fractionLong-term mortalityLV-GLSGlobal longitudinal strainTransthoracic echocardiographyFunctional recoveryLV global longitudinal strainMultivariable Cox survival analysisLarge single-center studyObstructive coronary artery diseaseVentricular global longitudinal strainHigher long-term mortalityLongitudinal strainMean troponin ISingle-center studyCoronary artery diseaseKaplan-Meier curvesCox survival analysisMajority of casesAnginal symptomsPrimary endpointAngiographic evaluationApical ballooningArtery diseaseEjection fraction
2018
Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain
Mentias A, Alashi A, Naji P, Gillinov AM, Rodriguez LL, Mihaljevic T, Suri RM, Grimm RA, Svensson LG, Griffin BP, Desai MY. Exercise capacity in asymptomatic patients with significant primary mitral regurgitation: independent effect of global longitudinal left ventricular strain. Cardiovascular Diagnosis And Therapy 2018, 8: 460-468. PMID: 30214861, PMCID: PMC6129839, DOI: 10.21037/cdt.2018.05.03.Peer-Reviewed Original ResearchRight ventricular systolic pressureLeft ventricular ejection fractionPrimary mitral regurgitationMean metabolic equivalentSignificant primary mitral regurgitationLV-GLSExercise capacityAsymptomatic patientsMitral regurgitationGlobal longitudinal left ventricular strainLeft ventricular global longitudinal strainMitral effective regurgitant orificeVentricular global longitudinal strainVentricular systolic pressureVentricular ejection fractionGlobal longitudinal strainFlail mitral leafletLeft ventricular strainEffective regurgitant orificeVelocity vector imagingVentricular strainEjection fractionIndependent predictorsSignificant arrhythmiasSystolic pressureLONG TERM OUTCOMES AFTER AORTIC VALVE SURGERY IN PATIENTS WITH ASYMPTOMATIC CHRONIC AORTIC REGURGITATION AND PRESERVED LEFT VENTRICULAR EJECTION FRACTION: ROLE OF PRE AND POST-OPERATIVE GLOBAL LONGITUDINAL STRAIN
Khullar T, Alashi A, Mentias A, Johnston D, Gillinov A, Rodriguez L, Svensson L, Popovic Z, Griffin B, Desai M. LONG TERM OUTCOMES AFTER AORTIC VALVE SURGERY IN PATIENTS WITH ASYMPTOMATIC CHRONIC AORTIC REGURGITATION AND PRESERVED LEFT VENTRICULAR EJECTION FRACTION: ROLE OF PRE AND POST-OPERATIVE GLOBAL LONGITUDINAL STRAIN. Journal Of The American College Of Cardiology 2018, 71: a2014. DOI: 10.1016/s0735-1097(18)32555-5.Peer-Reviewed Original ResearchPRESERVED LEFT VENTRICULAR EJECTION FRACTIONAsymptomatic chronic aortic regurgitationLeft ventricular ejection fractionAortic valve surgeryChronic aortic regurgitationVentricular ejection fractionGlobal longitudinal strainLong-term outcomesValve surgeryAortic regurgitationEjection fractionTerm outcomesRole of preLongitudinal strainRegurgitationPatientsSurgery
2017
Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction
Alashi A, Mentias A, Abdallah A, Feng K, Gillinov AM, Rodriguez LL, Johnston DR, Svensson LG, Popovic ZB, Griffin BP, Desai MY. Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Chronic Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction. JACC Cardiovascular Imaging 2017, 11: 673-682. PMID: 28624411, DOI: 10.1016/j.jcmg.2017.02.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic Valve InsufficiencyAsymptomatic DiseasesBiomechanical PhenomenaChronic DiseaseDisease ProgressionEchocardiography, Doppler, ColorFemaleHumansMaleMiddle AgedMyocardial ContractionPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular ejection fractionAortic valve surgeryChronic aortic regurgitationLong-term mortalityGlobal longitudinal strainRight ventricular systolic pressureVentricular global longitudinal strainLV end-systolic dimensionLV-GLSVentricular systolic pressureEnd-systolic dimensionVentricular ejection fractionAortic regurgitationAsymptomatic patientsTerm mortalityValve surgerySTS scoreEjection fractionSystolic pressurePrognostic utilityLeft ventricular global longitudinal strainMultivariable Cox survival analysisSevere chronic aortic regurgitationLongitudinal strainMean STS score
2016
Long-Term Outcomes in Patients With Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction
Mentias A, Feng K, Alashi A, Rodriguez LL, Gillinov AM, Johnston DR, Sabik JF, Svensson LG, Grimm RA, Griffin BP, Desai MY. Long-Term Outcomes in Patients With Aortic Regurgitation and Preserved Left Ventricular Ejection Fraction. Journal Of The American College Of Cardiology 2016, 68: 2144-2153. PMID: 27855803, DOI: 10.1016/j.jacc.2016.08.045.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionAV surgeryVentricular ejection fractionAortic regurgitationLong-term survivalEjection fractionSuch patientsLeft ventricleChronic severe aortic regurgitationSex-matched U.S. populationLV end-systolic dimensionMultivariate Cox survival analysisGreater aortic regurgitationHospital postoperative mortalityMean STS scoreThoracic Surgeons scoreAortic valve surgeryChronic aortic regurgitationSevere aortic regurgitationEnd-systolic dimensionSurvival of patientsLong-term outcomesRisk of deathCox survival analysisPostoperative mortalitySynergistic Utility of Brain Natriuretic Peptide and Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Primary Mitral Regurgitation and Preserved Systolic Function Undergoing Mitral Valve Surgery
Alashi A, Mentias A, Patel K, Gillinov AM, Sabik JF, Popović ZB, Mihaljevic T, Suri RM, Rodriguez LL, Svensson LG, Griffin BP, Desai MY. Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Global Longitudinal Strain in Asymptomatic Patients With Significant Primary Mitral Regurgitation and Preserved Systolic Function Undergoing Mitral Valve Surgery. Circulation Cardiovascular Imaging 2016, 9: e004451. PMID: 27342145, DOI: 10.1161/circimaging.115.004451.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsymptomatic DiseasesBiomarkersCardiac Surgical ProceduresChi-Square DistributionEchocardiographyFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMultivariate AnalysisMyocardial ContractionNatriuretic Peptide, BrainPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeVentricular Function, LeftVentricular Function, RightVentricular PressureConceptsLeft ventricular ejection fractionMitral valve surgeryVentricular ejection fractionLog-transformed BNPThoracic Surgeons scoreBrain natriuretic peptidePrimary mitral regurgitationRight ventricular systolic pressureSignificant primary mitral regurgitationVentricular systolic pressureGlobal longitudinal strainIncremental prognostic utilityLV-GLSAsymptomatic patientsValve surgeryEjection fractionMitral regurgitationSurgeons scoreNatriuretic peptideSystolic pressurePrognostic utilityBaseline LV global longitudinal strainBaseline right ventricular systolic pressureMitral effective regurgitant orificeLV global longitudinal strainOUTCOMES OF PATIENTS WITH ≥3+ AORTIC REGURGITATION AND PRESERVED LEFT VENTRICULAR EJECTION FRACTION: A SINGLE TERTIARY CARE CENTER EXPERIENCE
Mentias A, Feng K, Alashi A, Rodriguez L, Gillinov A, Sabik J, Svensson L, Griffin B, Desai M. OUTCOMES OF PATIENTS WITH ≥3+ AORTIC REGURGITATION AND PRESERVED LEFT VENTRICULAR EJECTION FRACTION: A SINGLE TERTIARY CARE CENTER EXPERIENCE. Journal Of The American College Of Cardiology 2016, 67: 2204. DOI: 10.1016/s0735-1097(16)32205-7.Peer-Reviewed Original ResearchPROGNOSTIC SIGNIFICANCE OF GLOBAL LONGITUDINAL STRAIN AND CORRECTION OF PRIMARY MITRAL REGURGITATION IN PATIENTS WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION
Alashi A, Mentias A, Patel K, Abdallah A, Popovic Z, Gillinov A, Suri R, Mihaljevic T, Sabik J, Svensson L, Griffin B, Desai M. PROGNOSTIC SIGNIFICANCE OF GLOBAL LONGITUDINAL STRAIN AND CORRECTION OF PRIMARY MITRAL REGURGITATION IN PATIENTS WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION. Journal Of The American College Of Cardiology 2016, 67: 1585. DOI: 10.1016/s0735-1097(16)31586-8.Peer-Reviewed Original Research