Reclassification of coronary heart disease risk in a primary prevention setting: traditional risk factor assessment vs . coronary artery calcium scoring
Alashi A, Lang R, Seballos R, Feinleib S, Sukol R, Cho L, Schoenhagen P, Griffin BP, Flamm SD, Desai MY. Reclassification of coronary heart disease risk in a primary prevention setting: traditional risk factor assessment vs . coronary artery calcium scoring. Cardiovascular Diagnosis And Therapy 2019, 9: 214-220. PMID: 31275811, PMCID: PMC6603493, DOI: 10.21037/cdt.2019.04.05.Peer-Reviewed Original ResearchReynolds Risk ScoreC-reactive proteinCoronary heart disease riskHeart disease riskPrimary preventionCHD riskAsymptomatic middle-aged patientsAsymptomatic middle-aged subjectsAtherosclerotic cardiovascular disease (ASCVD) scoreTraditional risk factor assessmentDisease riskMean C-reactive proteinCoronary artery calcium scoringConsecutive asymptomatic subjectsSignificant risk reclassificationCoronary artery calcificationMiddle-aged patientsRisk factor assessmentMiddle-aged subjectsStandard risk factorsASCVD scorePrevention clinicArtery calcificationCAC scoringAsymptomatic subjectsIncremental Prognostic Value of Exercise Stress Testing in Primary Prevention
Alashi A, Riaz H, Lang R, Seballos R, Feinleib S, Sukol R, Cho L, Cremer P, Jaber W, Griffin BP, Desai MY. Incremental Prognostic Value of Exercise Stress Testing in Primary Prevention. The American Journal Of Cardiology 2019, 124: 216-223. PMID: 31104779, DOI: 10.1016/j.amjcard.2019.04.021.Peer-Reviewed Original ResearchConceptsHeart rate recoveryIncremental prognostic valueC-reactive proteinPrimary preventionPrognostic valueLong-term eventsCV diseaseDerivation groupFamily historyValidation groupStandard risk factor assessmentProspective observational cohort studyContinuous net reclassification improvementConsecutive asymptomatic adultsPremature CV diseaseSuperior risk stratificationTreadmill stress testingFuture cardiovascular eventsObservational cohort studyExercise stress testingMultivariable survival analysisRisk factor assessmentNet reclassification improvementBeats/minStress testing