Successful Intravascular Correction of Intratumoral Pseudoaneurysm by Erosion of the Aorta in a Patient with Thoracic Giant Cell Tumor of Bone Responding to Denosumab
Fraile N, Toloi D, Kurimori C, Matutino A, Codima A, Camargo V, Feher O, Munhoz R. Successful Intravascular Correction of Intratumoral Pseudoaneurysm by Erosion of the Aorta in a Patient with Thoracic Giant Cell Tumor of Bone Responding to Denosumab. Case Reports In Oncological Medicine 2015, 2015: 626741. PMID: 26600960, PMCID: PMC4639671, DOI: 10.1155/2015/626741.Peer-Reviewed Original ResearchGiant cell tumorCell tumorsGiant cellsOsteoclast-like giant cellsInitiation of denosumabNuclear factor-kB ligandUnequivocal clinical improvementTumor stromal cellsMonoclonal antibody denosumabAdvanced GCTMultiple resectionsUnremarkable recoveryClinical improvementFirst doseSurgical resectionEndovascular approachAggressive neoplasmTherapeutic optionsAntibody denosumabStent placementOsteoclast activityDenosumabReceptor activatorActionable targetsStromal cells