Effect of Antibiotic Duration in Emergency General Surgery Patients with Intra-Abdominal Infection Managed with Open vs Closed Abdomen.
Diaz JJ, Zielinski MD, Chipman AM, O'Meara L, Schroeppel T, Cullinane D, Shoultz T, Barnes SL, May AK, Maung AA. Effect of Antibiotic Duration in Emergency General Surgery Patients with Intra-Abdominal Infection Managed with Open vs Closed Abdomen. Journal Of The American College Of Surgeons 2022, 234: 419-427. PMID: 35290260, DOI: 10.1097/xcs.0000000000000126.Peer-Reviewed Original ResearchConceptsIntra-abdominal infectionsOpen abdomenSecondary infectionAntibiotic durationClosed abdomenOA patientsExact testHigher Sequential Organ Failure AssessmentSequential Organ Failure AssessmentEmergency general surgery patientsChi-square/Fisher's exact testDuration of antibioticsAPACHE II scoreGeneral surgery patientsOrgan Failure AssessmentHigh rateAnesthesiologists physical statusFisher's exact testTwenty-one centersII scoreSurgery patientsOverall mortalityPrimary outcomeMean durationAntibiotic treatment