2024
Outcomes and Recurrence Rates Among Patients With Provoked and Cryptogenic Cerebral Venous Thrombosis
Al Kasab S, Almallouhi E, Shu L, Kicielinski K, Salehi Omran S, Liebeskind D, Zubair A, Vedovati M, Paciaroni M, Antonenko K, Heldner M, de Havenon A, Henninger N, Yaghi S. Outcomes and Recurrence Rates Among Patients With Provoked and Cryptogenic Cerebral Venous Thrombosis. Neurology Clinical Practice 2024, 15: e200381. PMID: 39399562, PMCID: PMC11464219, DOI: 10.1212/cpj.0000000000200381.Peer-Reviewed Original ResearchRisk of recurrent venous thromboembolismRecurrent venous thromboembolismCerebral venous thrombosisVenous thromboembolismFemale patientsVenous thrombosisBaseline characteristicsOutcome of cerebral venous thrombosisRate of recurrent venous thromboembolismProvoking factorsRare cause of strokeTransient provoking factorsKaplan-Meier survival analysisDuration of anticoagulationOutcomes of patientsMann-Whitney <i>Cause of strokeConsecutive patientsRare causeRecurrence rateMale patientsMulticenter studyRetrospective databaseStandard treatmentCox regressionIntravenous Thrombolysis in Patients With Cervical Artery Dissection: A Secondary Analysis of the STOP-CAD Study.
Shu L, Akpokiere F, Mandel D, Field T, Leon Guerrero C, Henninger N, Muppa J, Affan M, Haq Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, López-Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy Rivas R, Aziz Y, Mistry E, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Garcia J, Muddasani V, de Havenon A, Sanchez S, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Krupka D, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Tountopoulou A, Tentolouris-Piperas V, Martinez-Marino M, Carrasco Wall V, Indraswari F, El Jamal S, Liu S, Zhou M, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Wangqin R, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Intravenous Thrombolysis in Patients With Cervical Artery Dissection: A Secondary Analysis of the STOP-CAD Study. Neurology 2024, 103: e209843. PMID: 39298709, PMCID: PMC11415265, DOI: 10.1212/wnl.0000000000209843.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke symptomsCervical artery dissectionFunctional independenceIntravenous thrombolysisIschemic stroke symptomsStroke symptomsArtery dissectionIncidence of symptomatic intracranial hemorrhageIschemic strokeSymptomatic intracranial hemorrhageSuspected ischemic strokeClass III evidenceMedian ageSymptomatic ICHIntracranial hemorrhageSecondary analysisGuideline recommendationsICH riskIII evidenceFunctional outcomesPatientsThrombolysisCeADYoung adultsDissectionCerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study
Vedovati M, Shu L, Henninger N, Zubair A, Heldner M, Al Kasab S, Siegler J, Liebeskind D, Antonenko K, Yaghi S, Paciaroni M. Cerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study. Journal Of Thrombosis And Thrombolysis 2024, 57: 1008-1017. PMID: 38824485, PMCID: PMC11315801, DOI: 10.1007/s11239-024-02997-w.Peer-Reviewed Original ResearchCases of cerebral vein thrombosisVenous thromboembolismRisk of recurrent venous thromboembolismRadiological characteristics of patientsCerebral vein thrombosisRecurrent venous thromboembolismKaplan-Meier methodLog-rank testAbsence of headacheAll-cause-deathLogistic regression analysisCharacteristics of patientsCancer statusCohort studyPropensity score matchingConsecutive patientsAssociated with cancerRadiological characteristicsVein thrombosisStudy outcomesRecanalization rateOlder ageRisk factorsMultivariate analysisPatient managementEvaluation of Neuromuscular Provider Perceptions and Office Setup for Evaluating Patients With Disabilities
Zubair A, Mikhaiel J, Keller S. Evaluation of Neuromuscular Provider Perceptions and Office Setup for Evaluating Patients With Disabilities. Journal Of Clinical Neuromuscular Disease 2024, 25: 201-202. PMID: 38771232, DOI: 10.1097/cnd.0000000000000483.Peer-Reviewed Original ResearchPrevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT
Shoskes A, Shu L, Nguyen T, Abdalkader M, Giles J, Amar J, Siegler J, Henninger N, ElNazeir M, Al Kasab S, Klein P, Heldner M, Antonenko K, Psychogios M, Liebeskind D, Field T, Liberman A, Esenwa C, Simpkins A, Li G, Frontera J, Kuohn L, Rothstein A, Khazaal O, Aziz Y, Mistry E, Khatri P, Omran S, Zubair A, Sharma R, Starke R, Morcos J, Romano J, Yaghi S, Asdaghi N. Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT. Journal Of Stroke 2024, 26: 325-329. PMID: 38836280, PMCID: PMC11164588, DOI: 10.5853/jos.2023.02264.Peer-Reviewed Original ResearchCase-Control Study of Individuals With Small Fiber Neuropathy After COVID-19
McAlpine L, Zubair A, Joseph P, Spudich S. Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19. Neurology Neuroimmunology & Neuroinflammation 2024, 11: e200244. PMID: 38630952, PMCID: PMC11087026, DOI: 10.1212/nxi.0000000000200244.Peer-Reviewed Original ResearchConceptsInvasive cardiopulmonary exercise testingSmall fiber neuropathyCase-control studyFiber neuropathySkin biopsiesClinical response to treatmentNeurovascular dysregulationTreated with IVIGRetrospective chart reviewCase-control study of individualsRetrospective cohort studyResponse to treatmentCardiopulmonary exercise testingClass III evidenceMyalgic encephalomyelitis/chronic fatigue syndromeIVIG groupClinical responseNeuropathic symptomsChart reviewIVIGStudy of individualsCohort studyIII evidenceClinical trialsCOVID-19 illnessComparative analysis of energy expenditure and costs in neuroimaging
Signorile W, Mahajan A, Fulbright R, Zubair A. Comparative analysis of energy expenditure and costs in neuroimaging. Journal Of The Neurological Sciences 2024, 460: 123001. PMID: 38616465, DOI: 10.1016/j.jns.2024.123001.Peer-Reviewed Original ResearchExternal validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis
Klein P, Shu L, Lindgren E, de Winter M, Siegler J, Simpkins A, Omran S, Heldner M, de Havenon A, Abdalkader M, Al Kasab S, Stretz C, Wu T, Wilson D, Asad S, Almallouhi E, Frontera J, Kuohn L, Rothstein A, Bakradze E, Henninger N, Zubair A, Sharma R, Kerrigan D, Aziz Y, Mistry E, van Kammen M, Tatlisumak T, Krzywicka K, Aguiar de Sousa D, Jood K, Field T, Yaghi S, Coutinho J, Nguyen T. External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107720. PMID: 38614162, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107720.Peer-Reviewed Original ResearchConceptsCerebral venous thrombosisArea under the receiver operating characteristic curvePoor outcomeVenous thrombosisCentral nervous system infectionInternational retrospective studyNervous system infectionExternal validation cohortFocal neurological deficitsReceiver operating characteristic curvePoor outcome dataLevels of hemoglobinLack of follow-upPoorer outcome scoresConsecutive patientsClinical presentationRetrospective studyValidation cohortIntracerebral hemorrhageNeurological deficitsFollow-upOutcome scoresSystemic infectionLevels of glucoseInternational cohortUtilization of wearable technology to track functional changes in a patient with myopathy
Zubair A. Utilization of wearable technology to track functional changes in a patient with myopathy. Brain Circulation 2024, 10: 190-191. PMID: 39036302, PMCID: PMC11259317, DOI: 10.4103/bc.bc_104_23.Peer-Reviewed Original ResearchHTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations
Saab L, DiCapua D, Zubair A. HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations. Journal Of The Neurological Sciences 2024, 459: 122973. PMID: 38520941, DOI: 10.1016/j.jns.2024.122973.Peer-Reviewed Original ResearchHTLV-1-associated myelopathy/tropical spastic paraparesisMyelopathy/tropical spastic paraparesisHTLV-1Discussion of risk factorsInfected CD4+ T cellsCD4+ T cellsAdult T-cell leukemia/lymphomaSpastic paraparesisT-cell leukemia/lymphomaQuality of lifeOptimal patient outcomesHTLV-1 infectionSymptoms of weaknessManaging symptomsDuration of infectionLoss of bladder controlNonspecific symptomsT cellsLower extremitiesSensory disturbancePatient outcomesTherapeutic considerationsHAM/TSPProviral loadRisk factorsLong term quality of life follow-up and functional impairment study in patients with Hirayama disease
Zubair A, Mustafa R, Crum B. Long term quality of life follow-up and functional impairment study in patients with Hirayama disease. Journal Of The Neurological Sciences 2024, 459: 122952. PMID: 38484554, DOI: 10.1016/j.jns.2024.122952.Peer-Reviewed Original ResearchQuality of lifeHirayama diseaseDistal upper extremity musclesUpper extremity musclesSelf-reported outcomesFunctional outcome measuresExtremity musclesAttributes of patientsLong-term qualityOutcome measuresOutcomes of HDImpairment studyYoung adultsTerm qualityPatient yearsMotor neuron disordersFollow-upHirayamaAntithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study
Yaghi S, Shu L, Mandel D, Guerrero C, Henninger N, Muppa J, Affan M, Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Omran S, Crandall R, Lester E, Mena D, Arauz A, Nehme A, Boulanger M, Touze E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Field T, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Shahripour R, Guo X, Ghannam M, AlMajali M, Samaniego E, Sanchez S, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy-Rivas R, Aziz Y, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Velez F, Gracia J, Mudassani V, de Havenon A, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Ferreira V, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Quereshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Vassilopoulou S, Tentolouris V, Martinez-Marino M, Wall V, Indraswari F, Jamal S, Liu S, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K. Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study. Stroke 2024, 55: 908-918. PMID: 38335240, DOI: 10.1161/strokeaha.123.045731.Peer-Reviewed Original ResearchCervical artery dissectionInverse probability of treatment weightingIschemic stroke riskIschemic strokeAntiplatelet therapyArtery dissectionCox regressionOcclusive dissectionCervical artery dissection patientsStroke riskProbability of treatment weightingBenefits of anticoagulationOptimal stroke prevention strategyStroke prevention strategiesReducing ischemic stroke riskAnticoagulant therapyAntithrombotic treatmentProspective studyCross-over approachRandomized trialsAnticoagulationCompare outcomesPrevention strategiesTreatment weightingHigh riskVirology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis
Zubair A, McAlpine L, Gobeske K. Virology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis. Journal Of The Neurological Sciences 2024, 457: 122886. PMID: 38278094, DOI: 10.1016/j.jns.2024.122886.Peer-Reviewed Original ResearchPatients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis
Zubair A, Saab L, Scharer K, Khokhar B. Patients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis. Brain Circulation 2024, 10: 60-66. PMID: 38655443, PMCID: PMC11034440, DOI: 10.4103/bc.bc_17_23.Peer-Reviewed Original ResearchVitamin B12 injectionsB12 injectionsAmyotrophic lateral sclerosisFood and Drug Administration-approved treatmentPrescribed off-labelQuality of lifeProgressive motor neuron diseaseVitamin B12Pool of patientsMethylcobalamin injectionRandomized controlled trialsLateral sclerosisOff-labelMotor neuron diseaseDisease progressionPatientsMuscle functionSemi-structured interviewsImprove balance
2023
A Case of West Nile Encephalitis: Neuroimaging Findings and Clinico-Radiological Mismatch
Mikhaiel J, Mckenzie A, Saab L, Zubair A. A Case of West Nile Encephalitis: Neuroimaging Findings and Clinico-Radiological Mismatch. Cureus 2023, 15: e49727. PMID: 38161903, PMCID: PMC10757579, DOI: 10.7759/cureus.49727.Peer-Reviewed Original ResearchWest Nile neuroinvasive diseaseMagnetic resonance imagingWest Nile encephalitisNeuroinvasive diseaseCerebrospinal fluidNeurologic sequelaeArthropod-borne RNA virusRepeat magnetic resonance imagingLong-term neurologic sequelaeWhite matter signal changesAnti-seizure medicationsDiagnosis of sequelaeMonths of headacheFavorable clinical outcomeWhite matter signal hyperintensitiesAcute flaccid paralysisWhite matter changesNine-month followLimited clinical symptomsT2-weighted magnetic resonance imagesSignal intensity abnormalitiesSevere neurological diseaseGeneralized weaknessLymphocytic pleocytosisFurther seizuresFinancial Literacy Among Medical Trainees and Faculty: A Pilot Study
Zubair A, Sivakolundu D, DeVito M, Dewey J. Financial Literacy Among Medical Trainees and Faculty: A Pilot Study. Cureus 2023, 15: e44829. PMID: 37809136, PMCID: PMC10559332, DOI: 10.7759/cureus.44829.Peer-Reviewed Original ResearchFinancial literacyFinancial educationMedical traineesAcademic institutionsMedical education systemEducation systemEducation pathwaysGraduate educationEducation debtLiteracyEducationCareer stagesPersonal financesFurther trainingTrainingLimited trainingPilot studyTraineesAttendingsInstitutionsSocioeconomic climateMedical specialtiesFellowsSurveyFacultyPlasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions
Zubair A, Rethana M, Ma A, McAlpine L, Abulaban A, Munro B, Patwa H, Nowak R, Roy B. Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions. Journal Of Clinical Neuromuscular Disease 2023, 25: 11-17. PMID: 37611265, DOI: 10.1097/cnd.0000000000000439.Peer-Reviewed Original ResearchConceptsNeuro-immunological diseaseIntravenous immunoglobulinAutoimmune neurological disordersAutoimmune neuromuscular disorderAdult patientsElderly patientsNeurological disordersNeuromuscular disordersChronic inflammatory demyelinating polyradiculoneuropathyNational Inpatient Sample databaseNational Inpatient Sample datasetInflammatory demyelinating polyradiculoneuropathySafe therapeutic choiceRetrospective chart reviewAppropriate clinical settingSide effect profileDemyelinating polyradiculoneuropathyIVIG useChart reviewYounger patientsMyasthenia gravisEffect profileMedical historyPrimary diagnosisTherapeutic choiceLeg MRI as a Complementary Diagnostic Tool in the Assessment of Foot Drop
Torabi T, Zubair A, Nowak R, Tseng B, Haims A, Roy B. Leg MRI as a Complementary Diagnostic Tool in the Assessment of Foot Drop. Journal Of Clinical Neuromuscular Disease 2023, 25: 57-58. PMID: 37611274, DOI: 10.1097/cnd.0000000000000433.Peer-Reviewed Original Research“Hot nose” sign in brain death
Zubair A. “Hot nose” sign in brain death. Surgical Neurology International 2023, 14: 282. PMID: 37680934, PMCID: PMC10481819, DOI: 10.25259/sni_543_2023.Peer-Reviewed Original ResearchBrain deathArterial activityBrain death testingBrain-dead patientsExternal carotid arteryMotor vehicle accidentsSubdural hematomaEmergency roomBrainstem responseCarotid arteryAncillary testingBrain scansVehicle accidentsSkull baseDeath testingMeticulous examinationNoseDeathExaminationSignsHematomaHemorrhagePatientsArteryThe Impact of COVID-19 on Families With Pediatric Muscular Dystrophy Patients
Zubair A, Scharer K, Lembeck P, Ionita C, Roy B. The Impact of COVID-19 on Families With Pediatric Muscular Dystrophy Patients. Cureus 2023, 15: e41138. PMID: 37519528, PMCID: PMC10386847, DOI: 10.7759/cureus.41138.Peer-Reviewed Original ResearchPediatric patientsCOVID-19 pandemicMuscular dystrophyCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicParents/caregiversMuscular dystrophy patientsChart reviewCaregiver burdenHome ordersPerson visitsLong-term effectsNeuromuscular conditionsProvider careNeuromuscular disordersPatientsPsychosocial impactDystrophy patientsSchool closuresNeuromuscular disabilitiesMajority of familiesHealthcare servicesSocial distancing measuresCOVID-19Daily activities