2024
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations
Saab L, DiCapua D, Zubair A. HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations. Journal Of The Neurological Sciences 2024, 459: 122973. PMID: 38520941, DOI: 10.1016/j.jns.2024.122973.Peer-Reviewed Original ResearchHTLV-1-associated myelopathy/tropical spastic paraparesisMyelopathy/tropical spastic paraparesisHTLV-1Discussion of risk factorsInfected CD4+ T cellsCD4+ T cellsAdult T-cell leukemia/lymphomaSpastic paraparesisT-cell leukemia/lymphomaQuality of lifeOptimal patient outcomesHTLV-1 infectionSymptoms of weaknessManaging symptomsDuration of infectionLoss of bladder controlNonspecific symptomsT cellsLower extremitiesSensory disturbancePatient outcomesTherapeutic considerationsHAM/TSPProviral loadRisk factorsLong term quality of life follow-up and functional impairment study in patients with Hirayama disease
Zubair A, Mustafa R, Crum B. Long term quality of life follow-up and functional impairment study in patients with Hirayama disease. Journal Of The Neurological Sciences 2024, 459: 122952. PMID: 38484554, DOI: 10.1016/j.jns.2024.122952.Peer-Reviewed Original ResearchQuality of lifeHirayama diseaseDistal upper extremity musclesUpper extremity musclesSelf-reported outcomesFunctional outcome measuresExtremity musclesAttributes of patientsLong-term qualityOutcome measuresOutcomes of HDImpairment studyYoung adultsTerm qualityPatient yearsMotor neuron disordersFollow-upHirayamaPatients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis
Zubair A, Saab L, Scharer K, Khokhar B. Patients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis. Brain Circulation 2024, 10: 60-66. PMID: 38655443, PMCID: PMC11034440, DOI: 10.4103/bc.bc_17_23.Peer-Reviewed Original ResearchVitamin B12 injectionsB12 injectionsAmyotrophic lateral sclerosisFood and Drug Administration-approved treatmentPrescribed off-labelQuality of lifeProgressive motor neuron diseaseVitamin B12Pool of patientsMethylcobalamin injectionRandomized controlled trialsLateral sclerosisOff-labelMotor neuron diseaseDisease progressionPatientsMuscle functionSemi-structured interviewsImprove balance
2023
Imaging biomarkers in the idiopathic inflammatory myopathies
Zubair A, Salam S, Dimachkie M, Machado P, Roy B. Imaging biomarkers in the idiopathic inflammatory myopathies. Frontiers In Neurology 2023, 14: 1146015. PMID: 37181575, PMCID: PMC10166883, DOI: 10.3389/fneur.2023.1146015.Peer-Reviewed Original ResearchIdiopathic inflammatory myopathiesManagement of IIMMagnetic resonance imagingElectrical impedance myographyPositron emission tomographyInflammatory myopathiesMuscle ultrasoundExtra-muscular manifestationsMuscle strength testingQuality of lifeObjective assessmentMuscle inflammationPatient managementTreatment responseBetter objective assessmentMuscle damageMuscle healthResonance imagingEmission tomographyClinical settingMuscle diseaseBiomarkersImpedance myographyMyopathyFurther validation