2024
The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
Arutiunian V, Santhosh M, Neuhaus E, Borland H, Tompkins C, Bernier R, Bookheimer S, Dapretto M, Gupta A, Jack A, Jeste S, McPartland J, Naples A, Van Horn J, Pelphrey K, Webb S. The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives. Molecular Autism 2024, 15: 19. PMID: 38711098, PMCID: PMC11075235, DOI: 10.1186/s13229-024-00598-1.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderElevated gamma powerLow language skillsGamma powerResponses to speech stimuliLanguage skillsLanguage functionFirst-degree relativesSpectrum disorderClinical Evaluation of Language FundamentalsCo-occurring language impairmentSpeech stimuliCortical gamma-band oscillationsHigh gamma powerSex-balanced sampleGamma-band oscillationsSample of participantsNonverbal IQLanguage impairmentASD participantsTD controlsNeural profilesAutism phenotypeTD groupLanguage Fundamentals
2023
Frontal EEG alpha asymmetry in youth with autism: Sex differences and social–emotional correlates
Neuhaus E, Santhosh M, Kresse A, Aylward E, Bernier R, Bookheimer S, Jeste S, Jack A, McPartland J, Naples A, Van Horn J, Pelphrey K, Webb S, Network A. Frontal EEG alpha asymmetry in youth with autism: Sex differences and social–emotional correlates. Autism Research 2023, 16: 2364-2377. PMID: 37776030, PMCID: PMC10840952, DOI: 10.1002/aur.3032.Peer-Reviewed Original ResearchConceptsAutistic youthFrontal alpha powerMaternal depression historyIndividual differencesExternalizing behaviorsAlpha powerFrontal EEG alpha asymmetrySocial-emotional correlatesDepression historyEEG alpha asymmetryMental health behaviorsModel of riskAffective styleAutism featuresInternalizing symptomsASD diagnosisAlpha asymmetryAutistic femalesBehavioral indicesLevels of analysisAutistic malesEEG markersGroup differencesParticipant groupsASDThe Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study
Shic F, Barney E, Naples A, Dommer K, Chang S, Li B, McAllister T, Atyabi A, Wang Q, Bernier R, Dawson G, Dziura J, Faja S, Jeste S, Murias M, Johnson S, Sabatos‐DeVito M, Helleman G, Senturk D, Sugar C, Webb S, McPartland J, Chawarska K, Trials T. The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study. Autism Research 2023, 16: 2150-2159. PMID: 37749934, PMCID: PMC11003770, DOI: 10.1002/aur.3026.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial attention taskSchool-aged childrenAttention taskASD groupSpectrum disorderEye-tracking taskTotal T-scoreAttentional patternsAutism spectrumTD groupPresentation timeTrial feasibility studyGroup differencesPercent of timeOlder childrenTaskComparison groupToddlersT-scoreChildrenChildren 4Outcome variablesFaceCondition effectsDevelopment of peak alpha frequency reflects a distinct trajectory of neural maturation in autistic children
Finn C, Han G, Naples A, Wolf J, McPartland J. Development of peak alpha frequency reflects a distinct trajectory of neural maturation in autistic children. Autism Research 2023, 16: 2077-2089. PMID: 37638733, DOI: 10.1002/aur.3017.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutism Spectrum DisorderAutistic DisorderChildCognitionElectroencephalographyHumansConceptsPeak alpha frequencyAutism spectrum disorderCognitive abilitiesAutistic childrenNonverbal IQNeural maturationSpectrum disorderTypical age-related increaseAlpha frequencyDifferent developmental trajectoriesDistinct trajectoriesSample of childrenCurrent study clarifiesDiagnostic groupsNeurotypical childrenNeurotypical controlsBehavioral measuresDevelopmental trajectoriesDiagnostic statusAge-related increaseFunction of ageIQEffect of ageBivariate relationsPrevious findings
2011
Temporal dynamics reveal atypical brain response to social exclusion in autism
McPartland JC, Crowley MJ, Perszyk DR, Naples A, Mukerji CE, Wu J, Molfese P, Bolling DZ, Pelphrey KA, Mayes LC. Temporal dynamics reveal atypical brain response to social exclusion in autism. Developmental Cognitive Neuroscience 2011, 1: 271-279. PMID: 21731598, PMCID: PMC3125043, DOI: 10.1016/j.dcn.2011.02.003.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderEvent-related potentialsSocial information processingAtypical brain responsesLate slow waveSignificant social difficultiesSocial exclusionAttentional resourcesEmotional arousalPeer rejectionTypical peersTemporal processingSocial difficultiesBrain responsesComputerized gameOvert behaviorSpectrum disorderInformation processingSocial contextObjective measuresEarly componentAutismTemporal dynamicsChildrenTreatment approaches