Genomics of Obsessive-Compulsive Disorder—Toward Personalized Medicine in the Era of Big Data
Szejko N, Dunalska A, Lombroso A, McGuire JF, Piacentini J. Genomics of Obsessive-Compulsive Disorder—Toward Personalized Medicine in the Era of Big Data. Frontiers In Pediatrics 2021, 9: 685660. PMID: 34746045, PMCID: PMC8564378, DOI: 10.3389/fped.2021.685660.Peer-Reviewed Original ResearchPsychiatric Genomics ConsortiumCommon disease-common variant hypothesisCommon variant hypothesisContext of genomicsGenetic codeGenetic association studiesMultiple genesAssociation studiesGenomics ConsortiumPolygenic risk scoresGenomicsGenetic contributionMendelian randomizationPolygenic disorderPersonalized medicineObsessive-compulsive disorderUK BiobankNew pathwayOCD pathogenesisAvailable databasesGenesDisease-specific databasesChina Kadoorie BiobankPathwayCo-existing pathology