2024
External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis
Klein P, Shu L, Lindgren E, de Winter M, Siegler J, Simpkins A, Omran S, Heldner M, de Havenon A, Abdalkader M, Al Kasab S, Stretz C, Wu T, Wilson D, Asad S, Almallouhi E, Frontera J, Kuohn L, Rothstein A, Bakradze E, Henninger N, Zubair A, Sharma R, Kerrigan D, Aziz Y, Mistry E, van Kammen M, Tatlisumak T, Krzywicka K, Aguiar de Sousa D, Jood K, Field T, Yaghi S, Coutinho J, Nguyen T. External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107720. PMID: 38614162, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107720.Peer-Reviewed Original ResearchConceptsCerebral venous thrombosisArea under the receiver operating characteristic curvePoor outcomeVenous thrombosisCentral nervous system infectionInternational retrospective studyNervous system infectionExternal validation cohortFocal neurological deficitsReceiver operating characteristic curvePoor outcome dataLevels of hemoglobinLack of follow-upPoorer outcome scoresConsecutive patientsClinical presentationRetrospective studyValidation cohortIntracerebral hemorrhageNeurological deficitsFollow-upOutcome scoresSystemic infectionLevels of glucoseInternational cohort
2022
A comparison of simultaneous multislice and conventional diffusion tensor imaging techniques for ischemic stroke evaluation at 1.5T
Culleton S, Kolowori S, Roberts J, de Havenon A, DiBella E, McNally J. A comparison of simultaneous multislice and conventional diffusion tensor imaging techniques for ischemic stroke evaluation at 1.5T. British Journal Of Radiology 2022, 96: 20220222. PMID: 36469531, PMCID: PMC10997011, DOI: 10.1259/bjr.20220222.Peer-Reviewed Original ResearchMeSH KeywordsDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansIschemic StrokeReproducibility of ResultsSexually Transmitted DiseasesConceptsIschemic stroke evaluationStroke workupStroke evaluationMean diffusivityDiffusion tensorIschemic strokeStroke protocolAcute settingIschemic stroke detectionTreatment windowBlinded neuroradiologistsIRB approvalDiagnostic accuracyFractional anisotropyT MRIObserver 2Observer 1Interrater reliabilityT-testConventional diffusion tensorWorkupDTIAverage image qualityCharacteristic areaCoefficient of variationDeep Learning Applications for Acute Stroke Management
Chavva IR, Crawford AL, Mazurek MH, Yuen MM, Prabhat AM, Payabvash S, Sze G, Falcone GJ, Matouk CC, de Havenon A, Kim JA, Sharma R, Schiff SJ, Rosen MS, Kalpathy‐Cramer J, Gonzalez J, Kimberly WT, Sheth KN. Deep Learning Applications for Acute Stroke Management. Annals Of Neurology 2022, 92: 574-587. PMID: 35689531, DOI: 10.1002/ana.26435.Peer-Reviewed Original ResearchMeSH KeywordsDeep LearningHumansNeural Networks, ComputerNeuroimagingReproducibility of ResultsStrokeConceptsDeep machine learningDeep learning applicationsMedical image analysisDeep neural networksPixel-wise labelingAcute stroke managementReal-world examplesDL applicationsDL approachMachine learningLearning applicationsDL modelsNeural networkStroke managementLesion segmentationMaximal utilityImage analysisElectronic medical record dataInter-rater variabilityCause of disabilityMedical record dataRelevant clinical featuresStroke detectionAdvanced neuroimaging techniquesDecision making
2018
Magnetic Resonance Imaging and Clinical Factors Associated With Ischemic Stroke in Patients Suspected of Cervical Artery Dissection
McNally JS, Hinckley PJ, Sakata A, Eisenmenger LB, Kim SE, De Havenon AH, Quigley EP, Iacob E, Treiman GS, Parker DL. Magnetic Resonance Imaging and Clinical Factors Associated With Ischemic Stroke in Patients Suspected of Cervical Artery Dissection. Stroke 2018, 49: 2337-2344. PMID: 30355108, PMCID: PMC6208137, DOI: 10.1161/strokeaha.118.021868.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeCervical artery dissectionIntramural hematomaIschemic strokeArtery dissectionT1-weighted sequencesIMH detectionMagnetic resonance imaging/magnetic resonance angiographyGradient-recalled echoMethods Institutional review board approvalIschemic stroke pathogenesisCardiovascular risk factorsStroke sourcesInterrater reliabilityMultivariate Poisson regressionReview board approvalMagnetic resonance angiographyMagnetic resonance imagingStroke prediction modelsStroke pathogenesisAcute strokeCurrent smokingClinical factorsAtherosclerotic diseaseImaging findings