2021
MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy
Muddasani V, de Havenon A, McNally JS, Baradaran H, Alexander MD. MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy. Topics In Magnetic Resonance Imaging 2021, 30: 197-204. PMID: 34397969, PMCID: PMC8371677, DOI: 10.1097/rmr.0000000000000277.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingIschemic strokeComputed tomographyMR perfusionCore infarctDiffusion-weighted magnetic resonance imagingPerfusion-diffusion mismatchDegree of ischemiaNoncontrast Computed TomographyImproved imaging techniquesSalvageable brainSuperior diagnostic informationIschemic penumbraSymptom onsetAcute evaluationAppropriate imagingPatient selectionStroke therapyThrombolytic therapyPoor outcomePrognostic valueLeading causeEffective treatmentBetter outcomesEarly identification
2017
Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke
de Havenon A, Bennett A, Stoddard GJ, Smith G, Chung L, O'Donnell S, McNally JS, Tirschwell D, Majersik JJ. Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke. Stroke And Vascular Neurology 2017, 2: 1. PMID: 28959484, PMCID: PMC5435214, DOI: 10.1136/svn-2016-000057.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood PressureBlood Pressure DeterminationCerebral AngiographyCerebrovascular CirculationCollateral CirculationComputed Tomography AngiographyDisability EvaluationFemaleHumansIschemic StrokeMaleMiddle AgedNeuroimagingPatient AdmissionPerfusion ImagingPredictive Value of TestsPrognosisRecovery of FunctionRetrospective StudiesRisk FactorsTime FactorsConceptsBlood pressure variabilityProximal vessel occlusionAcute ischemic strokeIschemic strokeVessel occlusionNeurological outcomeBPV indicesPressure variabilityAcute anterior circulation ischemic strokeAnterior circulation ischemic strokeIntravenous tissue plasminogen activatorGood collateral vesselsIschemic core volumeLarger mismatch volumeWorse neurological outcomeAcute stroke therapySubset of patientsSystolic blood pressureTissue plasminogen activatorLogistic regression modelsOrdinal logistic regression modelsEndovascular thrombectomyIschemic penumbraStroke onsetStroke outcome