Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease
Liebeskind DS, Hinman JD, Kaneko N, Kitajima H, Honda T, De Havenon AH, Feldmann E, Nogueira RG, Prabhakaran S, Romano JG, Callas PW, Schneider DJ. Endothelial Shear Stress and Platelet FcγRIIa Expression in Intracranial Atherosclerotic Disease. Frontiers In Neurology 2021, 12: 646309. PMID: 33716947, PMCID: PMC7947292, DOI: 10.3389/fneur.2021.646309.Peer-Reviewed Original ResearchIntracranial atherosclerotic diseaseEndothelial shear stressFcγRIIa expressionAtherosclerotic diseaseFcγRIIA receptorsArterial stenosisAnti-platelet medicationAnti-platelet strategiesPotent risk factorLocal pathophysiologyRecurrent strokeRisk factorsCardiovascular diseaseVascular remodelingIndividual patientsPlaque growthPlatelet activationElevated expressionDiseasePlatelet interactionClinical realmRecurrent eventsStenosisDifferential activationLuminal wall