2024
Effects of a dietary intervention on cardiometabolic risk and food consumption in a workplace
Shrestha A, Tamrakar D, Ghinanju B, Shrestha D, Khadka P, Adhikari B, Shrestha J, Waiwa S, Pyakurel P, Bhandari N, Karmacharya B, Shrestha A, Shrestha R, Bhatta R, Malik V, Mattei J, Spiegelman D. Effects of a dietary intervention on cardiometabolic risk and food consumption in a workplace. PLOS ONE 2024, 19: e0301826. PMID: 38656951, PMCID: PMC11042715, DOI: 10.1371/journal.pone.0301826.Peer-Reviewed Original ResearchConceptsConsumption of whole grainsHealthy foodPre-post intervention studyWhole grainsMedian consumptionCardiovascular risk factor profileRisk factor profileBlood pressureWorksite settingWorksite interventionsUnhealthy foodsHealth programsMeasured blood pressurePre-hypertensionCardiometabolic riskDiastolic blood pressureIntervention studiesFactors dietPaired-t testFactor profileFasting glucose levelsDhulikhel HospitalHospital premisesEmployee healthHospital employees
2021
Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP)
Shakya P, Shrestha A, Karmacharya BM, Shrestha A, Kulseng BE, Skovlund E, Sen A. Diabetes Prevention Education Program in a population with pre-diabetes in Nepal: a study protocol of a cluster randomised controlled trial (DiPEP). BMJ Open 2021, 11: e047067. PMID: 34819277, PMCID: PMC8614149, DOI: 10.1136/bmjopen-2020-047067.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes MellitusGlycated HemoglobinHumansNepalPrediabetic StateRandomized Controlled Trials as TopicRisk FactorsConceptsDiabetes prevention education programIntervention armPrevention education programControl armRandom blood sugar valuesIndian Diabetes Risk ScoreNepal Health Research CouncilLifestyle intervention programDiabetes Risk ScoreBlood sugar valuesInstitutional Review CommitteeHealth Research CouncilKathmandu University SchoolWorkers/volunteersHealth Research EthicsDiabetes burdenStudy protocolHealthcare workersTwo-armHigh-income countriesOutcome measuresPhysical activityRisk scoreHealth literacyQualitative study
2020
Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol
Pyakurel P, Shrestha A, Karmacharya BM, Budhathoki SS, Chaudhari RK, Tamrakar D, Shrestha A, Karmacharya RM, Shrestha A, Sharma S, Sharma SK, Spiegelman D. Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol. Open Heart 2020, 7: e001236. PMID: 32847993, PMCID: PMC7451278, DOI: 10.1136/openhrt-2019-001236.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBlood GlucoseDiabetes MellitusGlycated HemoglobinHealth BehaviorHealth Knowledge, Attitudes, PracticeHealthy LifestyleHumansMaleMiddle AgedMulticenter Studies as TopicNepalOccupational Health ServicesPatient Education as TopicPrediabetic StatePrimary PreventionRandomized Controlled Trials as TopicRisk Reduction BehaviorTime FactorsTreatment OutcomeConceptsBehavioral interventionsControl periodDiabetes risk reductionMonth control periodNepal Health Research CouncilBehavioral intervention groupWorksite intervention studiesT-testHealth Research CouncilInstitutional review boardTwo-sample t-testBlood sugarTrial protocolIntervention groupEthical approvalControl groupIntervention studiesType 2More monthsReview boardInterventionDiabetesParticipant changesPublic healthRisk reductionNUrse-led COntinuum of care for people with Diabetes and prediabetes (NUCOD) in Nepal: study protocol for a cluster randomized controlled trial
Xu D, Dev R, Shrestha A, Zhang L, Shrestha A, Shakya P, Hughes JP, Shakya PR, Li J, Liao J, Karmacharya BM. NUrse-led COntinuum of care for people with Diabetes and prediabetes (NUCOD) in Nepal: study protocol for a cluster randomized controlled trial. Trials 2020, 21: 442. PMID: 32471476, PMCID: PMC7257188, DOI: 10.1186/s13063-020-04372-5.Peer-Reviewed Original ResearchMeSH KeywordsCluster AnalysisContinuity of Patient CareCost-Benefit AnalysisDiabetes Mellitus, Type 2Glycated HemoglobinHumansMulticenter Studies as TopicNepalNurse's RoleNursing ServicesOutcome and Process Assessment, Health CarePatient Education as TopicPrediabetic StateProgram EvaluationRandomized Controlled Trials as TopicRisk FactorsRisk Reduction BehaviorConceptsUsual treatment groupPrimary care centersType 2 diabetesManagement of diabetesRE-AIM frameworkImplementation outcomesContinuum of careUnit of randomizationLow-income settingsPrediabetes individualsTreat basisDiabetes nursesDiabetes preventionPrimary outcomeClinical outcomesHemoglobin levelsDiabetes individualsDiabetes programParallel groupStudy protocolCare centerIntervention groupTwo-armCare modelCare approach