High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately
Chen W, Wong C, Vosburgh E, Levine AJ, Foran DJ, Xu EY. High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately. Journal Of Visualized Experiments 2014, 51639. PMID: 25046278, PMCID: PMC4212916, DOI: 10.3791/51639.Peer-Reviewed Original ResearchMeSH KeywordsDrug Screening Assays, AntitumorHigh-Throughput Screening AssaysHumansImage Processing, Computer-AssistedNeoplasmsSoftwareSpheroids, CellularConceptsGraphical user interfaceLarge-scale image analysisImage analysis applicationsUser-friendly software applicationFree image analysis softwareImage analysisActive contour algorithmHigh-throughput image analysisHigh-throughput computationTime-consuming processUser interfaceSoftware applicationsImage analysis softwareAnalysis applicationsNumber of applicationsUneven illuminationQuality control workflowContour algorithmAnalysis softwareQuality imagesNoisy backgroundSoftwareAnalysis processImagesEasy quality control