2010
Stem cell therapeutics: potential in the treatment of inflammatory bowel disease
Swenson E, Theise N. Stem cell therapeutics: potential in the treatment of inflammatory bowel disease. Clinical And Experimental Gastroenterology 2010, Volume 3: 1-10. PMID: 21694840, PMCID: PMC3108654, DOI: 10.2147/ceg.s6836.Peer-Reviewed Original ResearchInflammatory bowel diseaseAllogeneic hematopoietic transplantationHost immune responseHematopoietic transplantationMesenchymal stem cellsBlood cell linesBowel diseaseImmune responseGenetic predispositionStem cellsLarge clinical trialsAutologous hematopoietic transplantationAutologous hematopoietic reconstitutionHost diseaseCrohn's diseaseMucosal immunityClinical trialsHematopoietic reconstitutionSmall seriesTransplantationGreater riskCell therapyDiseaseDonor cellsBaseline state
2009
Adenosine inhibits chemotaxis and induces hepatocyte‐specific genes in bone marrow mesenchymal stem cells
Mohamadnejad M, Sohail MA, Watanabe A, Krause DS, Swenson ES, Mehal WZ. Adenosine inhibits chemotaxis and induces hepatocyte‐specific genes in bone marrow mesenchymal stem cells. Hepatology 2009, 51: 963-973. PMID: 20044808, PMCID: PMC2840188, DOI: 10.1002/hep.23389.Peer-Reviewed Original ResearchConceptsMarrow-derived mesenchymal stem cellsHepatocyte growth factorMSC chemotaxisCellular injuryMesenchymal stem cellsAdenosine concentrationRegulation of HGFInhibition of HGFEffects of adenosineSite of injuryBone marrow-derived mesenchymal stem cellsHepatocyte-specific genesHigh adenosine concentrationsHuman marrow-derived mesenchymal stem cellsAdenosine monophosphateBone marrow mesenchymal stem cellsStem cellsMarrow mesenchymal stem cellsConcentration of adenosineLiver injuryCytosolic calcium signalingStress fiber formationA2A receptorsHepatocyte-like cellsCyclic adenosine monophosphate