Yale School of Medicine: Reaching Our Vision
September 29, 2022Information
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- 00:00Doctor Brown served for 9 years
- 00:01as the chair of the Department of
- 00:03Medicine at Vanderbilt Development of
- 00:05infrastructure to promote the career
- 00:07success of physician scientists.
- 00:09She founded the Vanderbilt Master of Science
- 00:11and Clinical Investigation program in 2000,
- 00:13served as associate Dean for clinical
- 00:15and Translational Scientist development
- 00:17at Vanderbilt from 2006 to 2010,
- 00:19and is the director of the Division of
- 00:22Clinical Pharmacology from 2009 to 2010.
- 00:24Doctor Brown's NIH funded research
- 00:26focuses on cardiovascular pharmacology
- 00:28and vascular biology and humans.
- 00:31She's particularly interested in
- 00:32understanding the mechanisms of
- 00:34antihypertensive and antidiabetic
- 00:35drugs that are peptidase inhibitors,
- 00:37including the angiotensin converting
- 00:39enzyme inhibitors,
- 00:40dipeptidyl peptidase 4 inhibitors,
- 00:43and neprilysin inhibitors.
- 00:45Our group has a loose stated not only
- 00:46how these drugs decrease inflammation,
- 00:48enhance fibrinolysis,
- 00:49the breakdown of blood clots,
- 00:51and improve glucose homeostasis,
- 00:52but also how they interact with one
- 00:54another and sometimes cause side effects.
- 00:56This understanding leads to
- 00:58optimizing outcomes in patients
- 01:00with hypertension and diabetes.
- 01:01Doctor Brown received her AB in molecular
- 01:04biophysics and biochemistry from Yale
- 01:05and her MD from Harvard Medical School.
- 01:07She completed her clinical training
- 01:09at a fellowship in clinical
- 01:10pharmacology at Vanderbilt University.
- 01:12Doctor Brown is a fellow of the American
- 01:14Association for the Advancement of
- 01:16Science and a member of the American
- 01:17Society of Clinical Investigation,
- 01:19the Association of American Physicians,
- 01:21the National Academy of Medicine,
- 01:23and the American Academy of
- 01:24Arts and Sciences.
- 01:25She is a master of the American
- 01:27College of Physicians and a Fellow
- 01:28of the Royal College of Physicians.
- 01:29She has served on the
- 01:31National advisory Research.
- 01:31Resources Council and the National Heart,
- 01:33lung and Blood Advisory Council of
- 01:35the National Institutes of Health.
- 01:36Doctor Brown currently serves on the
- 01:38Visiting committee for Harvard Medical
- 01:40School and the External Advisory
- 01:41Board for the Harvard MIT Health
- 01:43Sciences and Technology program.
- 01:44Finally,
- 01:45she's a member of the Scientific Advisory
- 01:47Board for Alnylam Pharmaceuticals.
- 01:50Thank you very much, Dean Brown,
- 01:51and cheers to take away.
- 01:53Thank you. Ariel and I will
- 01:54share some slides here.
- 02:03Can you all see those? Great.
- 02:05So thank you for the invitation to
- 02:07speak and and for those of you who
- 02:10have seen the state of the school,
- 02:11there will be some repetition,
- 02:13but some some updates as well.
- 02:16And the title of this is really
- 02:18to think with you about how we
- 02:21become all that we can, we can be.
- 02:24And I will start by reminding
- 02:28of our mission statement because
- 02:30everything that I'm going to talk
- 02:33to about today really derives.
- 02:35From this Commission first,
- 02:37that we educate and nurture creative
- 02:40leaders in medicine and science by
- 02:42promoting curiosity and critical
- 02:44inquiry in an inclusive environment
- 02:46which is enriched by diversity.
- 02:48Also that we advanced discovery
- 02:50and innovation fostered by
- 02:51partnerships across the university
- 02:53and our local community as well as
- 02:55other institutions in the world.
- 02:57And that we care for
- 02:59patients with compassion,
- 03:00but also commit to improving
- 03:02the health of all people.
- 03:03So as I think about the strategic planning.
- 03:06That we've done over the last 2 1/2 years,
- 03:09often in specific areas like education
- 03:12or research or clinical enterprise.
- 03:14There are several cross cutting
- 03:16themes that I'd like to highlight
- 03:18as we talked today and the first
- 03:21is this creation of an environment
- 03:23of inclusive excellence where every
- 03:25member of our Community can thrive.
- 03:27And to which we can continue to
- 03:29recruit the best talent in the world.
- 03:31We have amazing people at Yale,
- 03:34and much of our investments over
- 03:37the last few years is creating a
- 03:40culture that enables people to
- 03:42reach their full potential.
- 03:44And I'll talk a lot about how we
- 03:46are working on climate and how we're
- 03:48working on career development.
- 03:51A second cross cutting theme is the
- 03:54notion of breaking down silos across
- 03:56departments between the school and
- 03:59our Yale New Haven Health system,
- 04:01between the school and our other
- 04:04collaborators and the institution
- 04:06in the university.
- 04:08And by doing this,
- 04:09how we promote interdisciplinary research
- 04:11to increase the impact of our science.
- 04:14Our science has always been excellent.
- 04:16But we can do higher impact
- 04:19science through doing this.
- 04:20Related to that is building resources
- 04:24that serve biomedical discovery.
- 04:26So as a a School of Medicine,
- 04:28we are always thinking about
- 04:31recruiting talent,
- 04:32but we also need to build the cross
- 04:35cutting resources that enable discoveries.
- 04:36And so we'll talk about some of
- 04:39our investments in those areas.
- 04:41And then lastly,
- 04:43you know our clinical mission
- 04:45is extremely important.
- 04:47We provide care often for underserved
- 04:49in our community and we do that
- 04:52in our partnership with the owner
- 04:54even health system and we are
- 04:56working a great deal on,
- 04:57on aligning to become the premier
- 05:00academic health system that we can be.
- 05:03So we'll talk a little bit about leadership.
- 05:04As I say we we are in the business
- 05:07of recruiting talent and that
- 05:09means both excellence in research,
- 05:11education and clinical work,
- 05:12but also people who share the values
- 05:15of our school and who are leaders.
- 05:18This highlights some recent
- 05:19recruitments over the last few years,
- 05:22most recently for example Eric Weiner and
- 05:25joined us in February as the director
- 05:27of our Cancer Center investments
- 05:29in some of our research centers.
- 05:32Leadership Anton Bennett in
- 05:34molecular and systems metabolism,
- 05:37Carlos Fernandez Hernando in
- 05:38vascular biology and Therapeutics,
- 05:40and Akiko Osaki leading a new
- 05:43Center for infection and immunity.
- 05:45We've also recruited leaders both
- 05:48internally and externally into deputy
- 05:52Deans roles and I would highlight
- 05:54these three Bob Rorbach who is leading
- 05:57our efforts in professionalism and
- 05:59leadership development and really
- 06:01establishing an infrastructure where
- 06:03we can recognize when a faculty
- 06:06member or a staff member or even
- 06:08a student are struggling with
- 06:10issues around professionalism.
- 06:12We can recognize that early
- 06:14make early interventions.
- 06:15To really change our culture overall.
- 06:21Dante's joined us a little over a
- 06:24year ago from UT Southwestern and is
- 06:27bringing new processes and analytics
- 06:30that enable efficiencies and less,
- 06:33I would say.
- 06:36Bureaucracy for our faculty and then
- 06:39most recently, doctor Peggy McGovern
- 06:41has joined us as CEO of Yale Medicine
- 06:44and is our Deputy for Clinical Affairs.
- 06:47And we'll talk about what that has
- 06:49enabled in terms of alignment.
- 06:51In education, of course.
- 06:53John Francis joined us about
- 06:55November a year ago as our associate
- 06:57Dean for Student Affairs.
- 06:58Veronica Chang assumed the position
- 07:00of assistant Dean for admissions,
- 07:02and Marietta Vasquez became associate
- 07:05Dean for medical student diversity.
- 07:07There are other things going on in the
- 07:09campus outside the School of Medicine
- 07:11that impact on the School of Medicine.
- 07:13And one is the creation of a freestanding
- 07:17school of engineering and applied
- 07:19science led by Dean Jeff Brock,
- 07:21who has been a tremendous partner,
- 07:22and I'll talk about that as I talk
- 07:25about biomedical informatics.
- 07:26And the other is the full separation
- 07:29of the Yale School of Public Health,
- 07:31anticipated after the recruitment
- 07:33of the new Dean to become a self
- 07:36supporting and independent.
- 07:38Right now the School of Public
- 07:40Health is something in an in between
- 07:42situation where it is has a Dean
- 07:44appointed by the President and
- 07:46sets many of its own policies.
- 07:48But financially is acts as a department
- 07:51in the School of Medicine and Melinda
- 07:54Irwin has recently chaired a search
- 07:56and and there are finalists for that
- 08:00permanent Dean's position and our
- 08:02interim Dean is Melinda Pettigrew.
- 08:05So one of the ways that we create
- 08:08an environment that is inclusive is
- 08:11by celebrating the accomplishments
- 08:12of our faculty.
- 08:13And we often do this with traditional
- 08:16academic accomplishments as shown
- 08:17here election into the American
- 08:19Society for Clinical Investigation,
- 08:21National Academy, etcetera.
- 08:23Or large awards like the awards
- 08:27garnered by Doctor de Camilli and
- 08:30Doctor Ruttle and Doctor Cruz last year.
- 08:34But it but.
- 08:35Also in the recognition by our peers
- 08:37and so I would highlight our faculty
- 08:40who were honored with distinguished
- 08:42Political career awards and Mike
- 08:45Katie who received the David Leffell
- 08:48Prize for Clinical Excellence.
- 08:50We are making an effort to be more
- 08:54intentional about recognizing our staff
- 08:57who enable that mission that we started with.
- 09:01So we had some who received the
- 09:03Linda Lorimer award last year in
- 09:05the Department of Psychiatry and
- 09:07we've had three members of our staff
- 09:10recently complete the Emerge program,
- 09:12which is a leadership development program,
- 09:15again emphasizing career development.
- 09:18And we further communicate about
- 09:21the accomplishments of our faculty,
- 09:23staff and students through our
- 09:25weekly news and recognition.
- 09:27This goes out to our school,
- 09:28but we also now send it
- 09:31to our peer institutions,
- 09:32the Deans,
- 09:33and to our alumni as a way of of
- 09:36really highlighting everything
- 09:37that is going on here,
- 09:39because I think we've often been
- 09:42a little bit shy to do that.
- 09:44We actually track our communications
- 09:46to to know are we getting the word
- 09:49out about the impact of our faculty.
- 09:52And so for example,
- 09:55if you Googled Ms and inflammation,
- 09:58we had the top hit based on our one of
- 10:01the sometime second hit.
- 10:03Our stories that related to COVID
- 10:05have brought many people to the to
- 10:07our websites who are patients who
- 10:09can benefit from our healthcare.
- 10:11And so these are some examples of efforts.
- 10:14Not area. Let me turn it now to
- 10:18education and this will look familiar.
- 10:21It's our incoming class,
- 10:23which is just outstanding.
- 10:25And we continue to recruit a diverse
- 10:29group of students with about 24%
- 10:31this year from groups traditionally
- 10:34underrepresented in medicine and
- 10:36slightly more women than men and with
- 10:38many of our students having been born
- 10:41outside the United States and roughly
- 10:43about 14% of our students being first
- 10:45generation first in their family.
- 10:47Complete a college education and as
- 10:49you can see outstanding stores scores
- 10:52and coming from the top institutions.
- 10:55I'm particularly pleased that our
- 10:57students also when they leave here,
- 11:00if they leave here,
- 11:01go to the top institutions as well.
- 11:04And this is the example of where
- 11:08our students went after this year.
- 11:10In the education room,
- 11:12we are leading in in some particular
- 11:14areas and and one is in the use of
- 11:17technology received again and annotation
- 11:20as an Apple distinguished school for
- 11:22the the period of 2021 and 2024 and
- 11:25you could see Mike Schwartz there.
- 11:27He's often led these efforts.
- 11:30Umm.
- 11:31Since Jessica Illuzzi came
- 11:33in January of 2021,
- 11:36we've had she's engaged in taking a
- 11:40look at our medical education programs
- 11:43and has recently led strategic planning
- 11:46that identified 3 cross cutting themes.
- 11:49The first is the.
- 11:52Engagement of our students in attaining
- 11:55competency and and by that we mean,
- 11:58you know,
- 11:59our medical students benefit from the
- 12:03Yale system in having a great deal of.
- 12:07Choice and the ability to tailor
- 12:11your education.
- 12:12And.
- 12:15How you think about whether you're
- 12:17achieving your goals is something
- 12:19that we'd like to work on.
- 12:20We don't have grades.
- 12:22We believe that you are adults
- 12:24and you need to be able to.
- 12:28Do self evaluation.
- 12:29It's part of lifelong learning
- 12:31and so developing systems,
- 12:33including coaching systems
- 12:34that allow you to do that is
- 12:37one of the strategic goals.
- 12:40Included in that, as I mentioned,
- 12:41our coaches and so a little more hands-on.
- 12:48Ability to to get input beyond what
- 12:51you have now with the advisor program.
- 12:54The second domain is enhancing faculty
- 12:56engagement in the educational mission.
- 12:58And Jessica and others have done a lot
- 13:00of work in the last year making sure
- 13:02that we're adequately rewarding our
- 13:04faculty for their educational efforts,
- 13:06including changing how we fund effort
- 13:10for education and most recently,
- 13:13changing our definitions of our promotion
- 13:16tracks in the faculty handbook that still
- 13:19has yet to be approved by the corporation,
- 13:23but to acknowledge.
- 13:24Work that is innovative in
- 13:27leading educational programs,
- 13:29even when that work does not
- 13:32result in a scholarly production,
- 13:36although I think we can do much
- 13:38better again in getting the word out
- 13:40about the innovation going on here.
- 13:42And then building an environment that
- 13:45is more inclusive and by doing things
- 13:49like creating colleges for the students.
- 13:51I know many of you have been engaged
- 13:54in this work and others of you
- 13:56will be engaged in the next phase.
- 13:58We are coming up just a year away on a
- 14:01visit from LCME and I'm very grateful to
- 14:05our students who have completed a self study.
- 14:08We've been working on our
- 14:10DCI and now of course the.
- 14:12The Self Study group is reviewing
- 14:14all those materials.
- 14:16This is a lot of work.
- 14:18I hope that it is a labor of love
- 14:20for those of you who are involved it.
- 14:23It is,
- 14:24you know,
- 14:25obviously important to be accredited,
- 14:27but it's more important in that it gives
- 14:30us time to reflect and think about
- 14:33where we can continue to innovate and
- 14:35and provide the best medical education.
- 14:38Turning to culture and climate,
- 14:41one of the hallmarks of our
- 14:45efforts to develop faculty,
- 14:47but also to develop in particular those
- 14:49who have been underrepresented in medicine,
- 14:52is to make sure that we are
- 14:55meeting with faculty early enough,
- 14:57identifying their needs,
- 14:59helping reduce barriers.
- 15:01One of the things that I've heard
- 15:03most often when I've had listening
- 15:05meetings with faculty is they.
- 15:07They feel like they don't always
- 15:10get as much input as they need.
- 15:13Many of our departments have annual reviews,
- 15:16but when you look at whether they're
- 15:19really happening and whether they're
- 15:21as useful as they need to be,
- 15:22in some cases they have not.
- 15:24So we've worked to standardize this.
- 15:26The group that's on the right
- 15:29there has been involved in an
- 15:31iterative process with input from.
- 15:33Departments that that piloted a
- 15:36form that can be used as part of
- 15:39the annual meeting and this we've
- 15:42had very positive feedback and
- 15:44that people really felt that they
- 15:46received input that was helpful
- 15:47in their career development.
- 15:49So we are going live with this as
- 15:52of this month for this this academic
- 15:54year and asking our departments to
- 15:57reach some goals in completing this.
- 16:00The formal diversity and inclusion
- 16:03strategic plans are online at the office
- 16:08of EI and they include many features,
- 16:11again focused on active retention
- 16:13of our faculty as well as recruiting
- 16:17retention of our students into
- 16:19trainees and our trainees into faculty.
- 16:22One of the things that we've wanted
- 16:24to do is have some discipline around
- 16:26this work so that everyone isn't
- 16:27reinventing the wheel and part of that.
- 16:29Is sharing best practices,
- 16:31and so we've gathered a committee of.
- 16:36University vice chairs and champions.
- 16:38It's led by Darren Matamore and the
- 16:41goals there are to collect data that we
- 16:44can use to make continual improvement.
- 16:47I present data at our state of the school
- 16:49such as this that I'm showing here.
- 16:52This just shows the growth in
- 16:54representation of those groups
- 16:55traditionally underrepresented in medicine
- 16:57in the school over year over year.
- 17:00It was at 5 year intervals in
- 17:02the first few bars,
- 17:03but now year over year showing that we
- 17:05are seeing progress in recruiting and in
- 17:09promoting to the associate professor.
- 17:11Now we have to work on promoting
- 17:13to the professor level and similar
- 17:16data for our women. In medicine.
- 17:18And starting to show new data that
- 17:22to to look at other things other
- 17:24than just numbers of faculty,
- 17:26but including things like among our faculty,
- 17:30among our professors,
- 17:32what proportion of our professorships
- 17:34are endowed shares are held by
- 17:37women or those underrepresented
- 17:38in minority and medicine.
- 17:40And you can see that for the
- 17:43underrepresented medicine,
- 17:43it's actually a higher portion than
- 17:46the than the denominator about the
- 17:48same for about equivalent to the
- 17:51number of women who are professors.
- 17:52So we're consciously looking
- 17:54at those sorts of things.
- 17:56We are also doing a lot of work,
- 17:59or as I said around.
- 18:01Our environment and how do we
- 18:04respond if someone is noted to have
- 18:08struggling with with behavioral
- 18:10issues or those kinds of things.
- 18:13Those of you haven't go to the LAPD
- 18:17website and and read the processes
- 18:20that we use were very dedicated
- 18:22to making it feasible for somebody
- 18:24to come forward without fear of
- 18:27retaliation and to follow up and to
- 18:29try to get follow up to those who have.
- 18:32Move forward,
- 18:32we're also tracking what kinds of
- 18:35things we're seeing and these are data
- 18:37from Bob Rohrbaugh over the last year.
- 18:40And you can see the pie chart there
- 18:42that 77% of the concerns that are
- 18:45expressed are around professionalism.
- 18:47And I'll go into more detail,
- 18:48about 13% are around what I would
- 18:51call climate within a within a unit.
- 18:54About 3% are related to sexual
- 18:56harassment or Title 9,
- 18:58I should say Title 9 issues
- 19:00and those sorts of things, so.
- 19:02Looking drilling down in the
- 19:04professionalism categories disruptive
- 19:06or inappropriate behavior is by
- 19:08far the that the farthest the most
- 19:11prevalent and this is sometimes you
- 19:13know things in the category of anger
- 19:16management those sorts of things and.
- 19:20Recognizing this early and and finding
- 19:23often that there are underlying issues
- 19:26either in somebody's personal life
- 19:29or frustrations that are ongoing
- 19:32in the environment.
- 19:34So correcting those things,
- 19:36but then also giving faculty
- 19:38coaching to help them improve and
- 19:41change before something more serious
- 19:44happens. Some of these happen in the
- 19:46student and training environment.
- 19:48Some of them are related
- 19:49to compliance issues. Few.
- 19:51Related to harassment or bullying,
- 19:53so you can see the categorization.
- 19:55I'll point out that there are some
- 19:57that are sexual misconduct and
- 19:59harassment that we're seeing but that
- 20:01are not in the Title 9 category.
- 20:03In other words, where the Title 9
- 20:05Office has said this is not has
- 20:07not reached a level for our office.
- 20:09So we will make efforts to start to to
- 20:13get this information out a little bit more.
- 20:18Again, creating an inclusive environment,
- 20:20paying attention to the needs of our faculty.
- 20:22A common need for our faculty
- 20:25is support for child rearing,
- 20:27and in the past year we have increased
- 20:30extended our time for a paid leave for
- 20:33child rearing from 8 weeks to 12 weeks,
- 20:36in part leveraging a new Connecticut law.
- 20:40This is not easy because it creates
- 20:43other stresses in the system,
- 20:45for example, making sure that.
- 20:47We can provide adequate clinical
- 20:51coverage when we have small units that
- 20:53have just a small number of faculty.
- 20:55So we are recently convening a committee
- 20:58of members of FAC and administrators to
- 21:01think through how do we have consistency,
- 21:05consistent policies around such
- 21:08issues across departments.
- 21:10And then we have for many years now since
- 21:142014 tracked gaps in salary between.
- 21:18Between our male and female faculty
- 21:20members and where we see this is in our
- 21:24clinical departments as you can see here,
- 21:27perhaps the closing gap,
- 21:28but we also changed our methodology
- 21:30in the last year.
- 21:31And you can see the variance variables
- 21:33that go into this multivariate regression
- 21:35analysis and see those things that
- 21:38have the biggest impact on salary by
- 21:40far and away it's your subspecialty.
- 21:42So what is the double AMC median
- 21:45salary for someone,
- 21:47but there are other things that.
- 21:49Obviously it you know how much
- 21:51political work you do have an impact
- 21:53and so these things are all controlled
- 21:55for and yet we still have a gap.
- 21:57What we do with these data are look
- 21:59department by department and what
- 22:01we've found is that when we do that
- 22:04we are able to bring a department that
- 22:07may have gotten out of line back into
- 22:10line back to zero and and we in the
- 22:13process often identify systemic issues
- 22:16that we can address across departments.
- 22:19And this is just the the example of
- 22:22how we look at this by department
- 22:25and you can see this department was
- 22:27one that we focused on this year.
- 22:30I would point out that one of these
- 22:33departments that is at around zero
- 22:34was one that had a very large gap
- 22:36in salary just a few years ago.
- 22:40Let me turn now to our research mission.
- 22:43You know one of the questions is how do
- 22:45you track your success in research and
- 22:48ultimately you want to track impact.
- 22:50It's the number of drugs that you bring to,
- 22:54to patients or the number
- 22:57of deaths that you prevent.
- 22:59Those are very long-term things to track
- 23:01and you know we are now have drugs
- 23:03coming to market that are based on basic
- 23:06science research that was done 30 years ago.
- 23:09So we often track leading indicators
- 23:11like NIH funding shown here
- 23:13and you can see we're in that,
- 23:15you know, tightly.
- 23:19Clustered group in the four to 8 range
- 23:22and we bounce around between there.
- 23:24I would say we tend to be very high
- 23:27in the number of single investigator
- 23:30grants and that's a hard way to.
- 23:33Have large, have as big an NIH budget as
- 23:37we have and so we've been emphasizing.
- 23:40Again, interdisciplinary large grants
- 23:42and then this just shows the data
- 23:44by department and I think you know
- 23:46you can see that about half of our
- 23:49departments are in the top ten in
- 23:51NIH funding and you know many are
- 23:53year over year in the top one or two
- 23:55such as psychiatry and medicine.
- 23:57Our faculty of course also do research
- 24:00at the VA and it's a it's not an
- 24:04insignificant amount and the VA
- 24:06research program is a really wonderful.
- 24:10Resource,
- 24:10particularly for new investigators to
- 24:13to maximize their chance of getting funded.
- 24:17There are pressures on our research program
- 24:20beyond just getting funding support.
- 24:22One of those has been a decline in
- 24:25the number of graduate students and
- 24:28and postdoctoral fellows who of
- 24:30course are the future of discovery.
- 24:32And there are several factors
- 24:34that have come to bear.
- 24:35One is the influence of recent
- 24:41governmental policies around certain visa
- 24:44holders and particularly from China.
- 24:47The other is that we had,
- 24:49we had a number of training grants
- 24:52going through an NIH institute that is
- 24:55decreasing the number of training grants.
- 24:57So as an interim solution,
- 24:59the School of Medicine along with
- 25:01the Graduate School is funding slots
- 25:03to maintain our ability to train
- 25:06graduate students and postdoctoral
- 25:08fellows while we come up with
- 25:11other solutions to fund slots,
- 25:13such as through endowment
- 25:15or through collaborations.
- 25:17With industry and those sorts of things.
- 25:21We are working to increase the diversity
- 25:24of our postdoctoral fellows as well.
- 25:26And one of the things that we
- 25:29appreciate is that often the best
- 25:31way to grow talent is to invest
- 25:33early and then retain that talent.
- 25:36And so you,
- 25:37fat Levy and Kristen Brennan are
- 25:39leading a new program called
- 25:41the Science Fellows Program,
- 25:42which creates the ability to recruit
- 25:46those superb postdoctoral fellows
- 25:48and groom them for transition to
- 25:51independence as faculty members.
- 25:53This is envisioned to be cluster hires,
- 25:55so that you're bringing in two or
- 25:58three or four fellows at the same
- 26:00time who are working in related areas.
- 26:03We are also spending a lot of effort
- 26:06on enabling our physician scientists.
- 26:09This effort has been led by Keith Tote,
- 26:12but also Nee Addy and Nick Click
- 26:16Light who have created huge resources,
- 26:19both salary support for people
- 26:22beginning their careers,
- 26:24mechanisms to make sure that mentorship
- 26:26is working,
- 26:26access to grant writing resources,
- 26:29and the creation of the Janeway Society,
- 26:30which brings together all of our
- 26:33junior faculty.
- 26:34To talk about how one starts a research
- 26:38program. What are the barriers?
- 26:39What? How?
- 26:40How does one navigate those barriers?
- 26:43We've created a successful grant
- 26:45library so that those who are
- 26:47submitting grants can can learn
- 26:49from others who have
- 26:51submitted successful grants.
- 26:52And this is just the types of grants
- 26:54that are included in that library.
- 26:56And it it could not happen without
- 26:58the generosity of our faculty who
- 27:00are willing to share their grants,
- 27:02including those that were not initially
- 27:04funded and then got funded so we
- 27:07can see how they responded to it,
- 27:09to the comments from reviewers.
- 27:13They have also developed mock study
- 27:16sections and again the generosity
- 27:18of many faculty who who participate
- 27:20in those and review grants together.
- 27:22And that ensures that when someone
- 27:25then finally submits the grant to
- 27:27the National Institutes of Health,
- 27:28it is the best possible grant
- 27:30that could go out the door.
- 27:31And that enables them to get be more
- 27:35likely to be funded the first time
- 27:38through and shorten that time to funding.
- 27:40Linda Bockenstedt has led an an effort
- 27:43to look at our research faculty.
- 27:45This is a track that is fundamental
- 27:47to many research programs.
- 27:49These are our faculty who have
- 27:52particular expertise in methods
- 27:54but perhaps don't desire to have an
- 27:57independent research program and
- 27:58the stresses of writing grants.
- 28:01And but the issue that we have with this
- 28:03track is that it's used in different ways,
- 28:05and there's often a disconnect
- 28:07between the expectations of a faculty
- 28:09member and the expectations of.
- 28:11Their principal investigator.
- 28:12So that committee has made
- 28:14a number of recommendations.
- 28:16One is to clarify those expectations,
- 28:18expectations at the outset of the
- 28:21standard offer letter to create
- 28:23individual pathways within this track
- 28:26to do a better job of mentoring
- 28:28this group of faculty,
- 28:29including using a form like the F
- 28:32DAC that we've developed and so
- 28:35that we're in the process of
- 28:37implementing those sorts of things.
- 28:39Again,
- 28:39as a way to increase the types
- 28:41of faculty we're developing,
- 28:43we have had an effort in biomedical
- 28:45data science.
- 28:46There's a real shortage of people
- 28:48who have expertise in this area.
- 28:50The students who are interested in this,
- 28:52I would encourage you to pursue
- 28:54those interests.
- 28:55But this is a program in collaboration
- 28:57with Burner Ingelheim where we have
- 28:59grown it actually more rapidly than
- 29:02anticipated because it's been so
- 29:04successful and each student has
- 29:06reach fellow has.
- 29:08Mentor within the university and
- 29:10a mentor within Barringer Anaheim,
- 29:12allowing them to cross fertilize.
- 29:16We have also recently recruited
- 29:18Lucilla Ana Machado,
- 29:19a member of the National Academy
- 29:21of Medicine to lead what will start
- 29:23as a freestanding section of
- 29:25biomedical informatics and data science,
- 29:27but evolve into a new department.
- 29:30And Lucilla has been on campus quite a bit,
- 29:34will be here today and tomorrow
- 29:37really working.
- 29:38And how we build better support for
- 29:41our faculty, our students,
- 29:43in terms of biomedical informatics.
- 29:45And I'm aware that our students are
- 29:47frustrated about access to J DAT,
- 29:49and this is something that we still
- 29:52will be able to help with.
- 29:54We are in in the realm of cross
- 29:58cutting research.
- 29:59We recently stood up a Yale Center
- 30:01for Brain and Mind Health.
- 30:03As you know, we have very
- 30:05strong neuroscience here.
- 30:06The Woosah Institute was created
- 30:08to study human cognition.
- 30:10Yale New Haven Health System
- 30:13is building a new neuroscience
- 30:15tower for clinical neuroscience.
- 30:17And there was a real need to create.
- 30:22Mechanisms to bring discovery
- 30:24into trials for our patients
- 30:26and to learn from our patients.
- 30:28And so this group of five faculty
- 30:32members representing neurosurgery,
- 30:34the Child Study Center,
- 30:36psychiatry and neurology.
- 30:38Interviewed all of the stakeholders,
- 30:40convened a retreat,
- 30:42strategic retreat and conceived
- 30:45of this center,
- 30:47which will create resources and bring
- 30:50people here to translate discovery
- 30:53into our into the clinical realm.
- 30:56We have some roadblocks in that area.
- 30:58One is that our our contracting
- 31:01and our time to initiation
- 31:04of clinical trials is slow.
- 31:07Just the goal is that this
- 31:08would happen within 90 days.
- 31:09You can see over this two year
- 31:11period that the vast majority of
- 31:13contracts and initiations took longer.
- 31:15We have a group that's working on this.
- 31:17We have some things that we need to
- 31:20tweak within the School of Medicine
- 31:22before we can really fix this.
- 31:24We're investing in, as I said,
- 31:27resources to enable everybody's research.
- 31:30One is a biorepository,
- 31:32where we're collecting samples
- 31:34from patients and keeping them
- 31:37stored appropriately,
- 31:38processed and stored appropriately so
- 31:40that investigators can access them.
- 31:42Two of the higher technology
- 31:45cores that we are just standing
- 31:47up is first A-fib SEM core,
- 31:50being led by Shanzu and song.
- 31:53Saying who we were very fortunate
- 31:56to recruit from Janelia Farm and
- 31:58who have developed mechanisms
- 32:01using fibs them to image cells down
- 32:05to the to the for Micron level
- 32:09incredible resolution leading them
- 32:11to be able to publish for example
- 32:14in a collaborative group the the
- 32:16connectome of the dress Drosophila
- 32:19brain so really impressive work
- 32:21and similarly a new Murphy.
- 32:24Multiplexed fish for transcriptome imaging,
- 32:27led by money dekmar that's
- 32:29available to all of our resources.
- 32:34Ironically, at this point our research
- 32:37enterprise is not constrained by money,
- 32:39but by space. We have a space plan.
- 32:44In in place, and I would say we have it.
- 32:48It's been somewhat frustrating because
- 32:51we are already behind schedule
- 32:54largely due to labor shortages and
- 32:56supply chain shortages post COVID.
- 32:59We just had a walk through of 300,
- 33:01George again this morning to think about
- 33:04what we need to do to improve this building.
- 33:07But you can see that after we
- 33:10complete renovations in this building
- 33:12and build out four floors and 100.
- 33:14College we will be building
- 33:16out floors in 101 college,
- 33:19the School of Public Health will
- 33:22be consolidating some of its.
- 33:24Classroom space.
- 33:25We will have backfill space related to
- 33:29this work that we can then renovate.
- 33:31This is the the.
- 33:34Preparation for another building,
- 33:36which is to move the School of
- 33:39public health classrooms into 300
- 33:42George temporarily so that we can.
- 33:46Plan for a new building in this
- 33:50strip mall area that's that's
- 33:52now used for classrooms.
- 33:53That will be very exciting.
- 33:54It will allow us to cross bridges
- 33:57here and what the students might
- 33:59observe is that then you start to see
- 34:02lines here over at Harkness Hall.
- 34:04I think all of us know that Harkness
- 34:07Hall is outlived its useful life and we
- 34:10have plans to to renovate that eventually.
- 34:13But you can see by the timeline that that's.
- 34:16Getting passed when you guys are here.
- 34:20Even I hope for the MD,
- 34:21PhD students who are on the call.
- 34:23So.
- 34:24We also this December will convene
- 34:27for the first time a scientific
- 34:31Advisory Board comprised of,
- 34:34you know, Nobel laureate,
- 34:36several Lasker winners,
- 34:38leaders in industry and interestingly I
- 34:41think all but one have a Yale association,
- 34:44maybe all of them do,
- 34:46which was not something we know.
- 34:48Charles Sawyers, I believe this is not,
- 34:50not something we intended to do,
- 34:52but happened by chance and and so we're
- 34:54looking forward to seeking their advice.
- 34:56On how we can do things a little bit better.
- 35:00Lastly, looking at the clinical mission,
- 35:03you know what academic health
- 35:05systems have traditionally done.
- 35:07Is offer access to cutting edge care,
- 35:11whether that's chemotherapy or at Yale,
- 35:14you know.
- 35:15Closed loop insulin pumps,
- 35:18transplant imaging,
- 35:20etcetera.
- 35:20But what increasingly academic health
- 35:24systems are able to do is also offer
- 35:28population health that increases
- 35:30the health of our entire community.
- 35:33And we have amazing physician nurses
- 35:37staff in our academic health system.
- 35:41One piece of evidence for that is that
- 35:44we were among all of the hospitals in
- 35:47the country in the top 24 for having
- 35:50the lowest mortality rate during COVID.
- 35:52And so I hold this out as an example of what
- 35:56we can do when we are all working together.
- 36:00It is not,
- 36:01however,
- 36:02always what we do,
- 36:03and although we offer excellent care,
- 36:07we often offer it in silos
- 36:09and not in a coordinated way,
- 36:11and we also often don't
- 36:14measure what we're doing so
- 36:16this. Slide which shows where we are in
- 36:19NIH ranking and has a number of NR not
- 36:22ranked and has a number of levels below
- 36:2510 is not what Yale School of Medicine
- 36:30or you only Haven Health should aspire
- 36:33to and the reason for this is that.
- 36:35As I say, we are not working together.
- 36:37We're still working in silos.
- 36:40We have tremendous opportunity when
- 36:42you look at where we are represented
- 36:45across the state of Connecticut.
- 36:48The state of Connecticut has demographics
- 36:50that mirror the rest of the country
- 36:53and we have both some of the wealthiest
- 36:56communities in the country as well as the
- 36:59largest disparities in income in the country.
- 37:03So as a.
- 37:04Place where we can have impact
- 37:07across a diverse set of communities.
- 37:10This is a wonderful place to be.
- 37:13And so we need to realize that ability to
- 37:16improve health across all of our communities.
- 37:19We also have a financial relationship
- 37:21with our clinical enterprise.
- 37:22We we support our research and our
- 37:26educational mission in part through our
- 37:29revenues from the clinical enterprise
- 37:31and those have been growing and we
- 37:34expect that they will not continue
- 37:36to grow at that same rate rate.
- 37:38So we have to work smarter.
- 37:40One of the reasons is that we have an
- 37:42aging population and and more of our
- 37:46older patients are shifting from commercial.
- 37:49Insurance tends to pay better to Medicare,
- 37:51where hospitals often lose money
- 37:54on the care of patients.
- 37:56We also have lost some patients that
- 37:59we think are the patients we should
- 38:02see that is the patients in in.
- 38:04Requiring tertiary and quaternary
- 38:06care to hospitals that we feel are
- 38:09less equipped to care for them,
- 38:10and so we need to reverse that.
- 38:13So we are engaging in a significant
- 38:16effort around realigning this,
- 38:18the School of Medicine and Neal New Haven
- 38:22Health system as an academic health system.
- 38:25Very grateful to have the
- 38:27partnership of Chris O'Connor,
- 38:29the CEO for Yale New Haven Health System.
- 38:32And a number of people have been working on
- 38:36this for the first time in memorable history.
- 38:40We are developing a shared strategic plan.
- 38:44And one of the things that I would
- 38:46highlight is these are the pillars
- 38:48that the group has identified and in
- 38:51the highest ranking both among our,
- 38:53our.
- 38:53With medicine colleagues on this committee,
- 38:56but also among our hospital members
- 38:59of this committee,
- 39:00leading Edge research was important
- 39:02and and and actually came out on top.
- 39:06But providing access to our patients,
- 39:09you know,
- 39:09you can provide the best possible care,
- 39:11but if a patient can't access it,
- 39:13it doesn't do them any good.
- 39:16Providing exceptional value that
- 39:18that allows all in the community
- 39:22to benefit and then of course
- 39:26cultivating our educational missions.
- 39:29And so you'll see some of the cross
- 39:32cutting foundational elements here.
- 39:34We also are doing some work,
- 39:36although I think this is an area
- 39:38that we have much more work to do to
- 39:41coordinate our operations where we have.
- 39:45We're not working in parallel,
- 39:47but we're working together.
- 39:48So once we have that strategic plan,
- 39:50we're following the same
- 39:52data we're following.
- 39:53We're not having duplication of
- 39:55things that will allow us to provide
- 39:58better service and also to be.
- 40:03To lower expenses, frankly and and
- 40:05these are some of the people that
- 40:07will be involved in that work.
- 40:09And then we're thinking about how we
- 40:12align the physician practice plan beyond
- 40:15medicine with the employed practice
- 40:17plan NE Medical Group so that we are
- 40:21working together and that a patient
- 40:23is getting care that is seamless and
- 40:26not fragmented and we have some very.
- 40:30Significant work that you'll hear
- 40:32about within the next two months
- 40:35or so in which we're going to do
- 40:37this and and stay tuned for that.
- 40:40Lastly, we have to.
- 40:43Make our funds flow between the hospital
- 40:46and the School of Medicine rational.
- 40:48This is a cartoon of the many,
- 40:51many agreements we have back and forth,
- 40:54which is crazy.
- 40:55And so we're thinking about how do we
- 40:58create a fund flow model that aligns
- 41:01incentives and where people get paid
- 41:03for their work and and it's not a one
- 41:06off negotiation where it's fairly
- 41:08formulaic and those things have a
- 41:10huge impact on our ability to fund.
- 41:13An educational system for example,
- 41:15and and fund our research,
- 41:17just say a little bit about finance.
- 41:20I mentioned that Arnie Donton joined
- 41:24in July of 2021 and discovered
- 41:29why we recruited him,
- 41:32which is that we have a lot of
- 41:34work to do around getting seamless
- 41:36processes in place and analytics
- 41:38to enable our core missions.
- 41:40And so this is his mission
- 41:43statement and vision.
- 41:44But when there's been
- 41:46failure of those processes,
- 41:48it has pretty dramatic consequences.
- 41:52And so some of you are aware that
- 41:54we had a $40 million theft over a
- 41:56period of about 10 years dating back
- 41:59to 2012 in one of our departments.
- 42:01That cannot happen unless you have
- 42:04failure in many places in the system.
- 42:07It's it's not unlike this,
- 42:09the safety analysis we do in the
- 42:12hospital when there's been an adverse event.
- 42:14And so it was everything from
- 42:17oversight of individuals to how we
- 42:19train people to how the controls work
- 42:22that some of which are centralized
- 42:24to how we could see the data.
- 42:26And one of the things that our work in
- 42:30correcting these has has highlighted
- 42:33is around climate and the fact that
- 42:36many of us don't feel like it's our
- 42:39job to to pay attention to these things.
- 42:41And it does seem mundane and.
- 42:44It doesn't seem like it's
- 42:46directly related to what you do,
- 42:47but I will tell you that it it is.
- 42:49And so you know,
- 42:50these are some of the things
- 42:52that we've heard from.
- 42:55Senior faculty sometimes.
- 42:57And my favorite is do you know who I am?
- 43:00And you know,
- 43:01there's an arrogance associated
- 43:02with that that should never be
- 43:03part of Yale School of Medicine.
- 43:05And it goes back to what we were
- 43:07talking about around professionalism.
- 43:09While we're talking about money,
- 43:10I will mention that we are in
- 43:13the midst of a capital campaign.
- 43:15One of the goals of that campaign is
- 43:18to raise money for financial aid to
- 43:21make our School of Medicine truly debt free.
- 43:25We have had a decline in our.
- 43:29That of our students are median
- 43:32debt of our students is around
- 43:35in this past year 79,000 compared
- 43:38to a much higher number.
- 43:40Average is more like 110,000 I believe
- 43:44compared to a national average of about 204.
- 43:47That should get the median should
- 43:49get closer to 60 as we start
- 43:52to realize the capping,
- 43:53the benefit of capping the unit loan.
- 43:55But of course we'd like to get
- 43:58that number down to zero and so.
- 44:00We we also have an opportunity to match funds
- 44:03and create a quasi endowment to do that.
- 44:06This takes time, but but it's a high
- 44:09priority in our capital campaign.
- 44:11And just to show you that we are starting
- 44:14to reap the benefits of that campaign.
- 44:16With an increase in in funding
- 44:19over the last three years.
- 44:21So I've talked about a lot of specific
- 44:24elements around the three missions.
- 44:27I would add the 4th mission,
- 44:28which is how we develop people,
- 44:30whether it's our students
- 44:32or trainees or our faculty.
- 44:33And I've shared with you some cross
- 44:35cutting themes about how we will
- 44:37do that to realize our vision.
- 44:38I think we've allowed plenty of time
- 44:40for questions and I will stop sharing.
- 44:46Thank you so very much, Dean Brown.
- 44:48If anyone has any questions, it's viewing.
- 44:51I haven't seen any so far, but there
- 44:52is an in the bottom part in the chat.
- 44:55There should be a question and answer
- 44:57area and people can put in their
- 45:00questions and we can try to answer them.
- 45:04Not seeing anything so far you.
- 45:07People may may want to take a a
- 45:09lunch break, so that's OK too.
- 45:22While we're waiting to see if
- 45:23anyone does have some questions
- 45:24that they'd like to submit,
- 45:25I'd just like to take the time
- 45:27to thank you, Dean Brown,
- 45:28again for coming and speaking.
- 45:29It's always a pleasure to get to work
- 45:31with you and to get to see all the
- 45:33fantastic work that you and everyone
- 45:34here is doing to try to further the
- 45:36training and the opportunities and
- 45:38the culture here at the schools.
- 45:39Very inspiring.
- 45:40So thank you very much.
- 45:41You have a great team. So.
- 45:44And and I and again thank you as you
- 45:47know because we meet in the MSC,
- 45:49but I I think that. You know,
- 45:52one of the philosophies of the
- 45:54old system is that you are future,
- 45:57future colleagues and you very much,
- 45:58the students are very much
- 46:00been part of this effort. So.
- 46:02Yes, that is. I very much felt that
- 46:04and experience that myself and I know
- 46:06many of my other classmates have,
- 46:08so we're very excited about.
- 46:11Question in the chat,
- 46:12do you have any thoughts on
- 46:14the future Yale Health CEO?
- 46:15So many of you may have seen the
- 46:17announcement that Paul Jennison is
- 46:19stepping down and there's now a
- 46:21national search for that position.
- 46:24I I and Peg McGovern, our CEO of your
- 46:28medicine is on that search committee.
- 46:29I think we have tremendous opportunity.
- 46:31It's a, it's a little bit
- 46:34unusual to have a separate.
- 46:36To have the the health plan for the
- 46:40university separate from the faculty
- 46:42practice plan to the extent that they are,
- 46:46and I think we can.
- 46:48We can work when the new leader
- 46:51is in place in ways that will
- 46:54increase efficiency and access
- 46:56again for our university community,
- 46:58at the same time making sure that
- 47:01we're providing the best value
- 47:03care about based care that we can.
- 47:24You don't see any more questions
- 47:26coming in at the moment,
- 47:27but for the MSC perspectives,
- 47:29our theme this year is equity and access
- 47:31and it's fantastic just how much of
- 47:33the schools principals align with that
- 47:35based on what you've been speaking about
- 47:37today and what our experiences have been.
- 47:39So would like to tune in in the future.
- 47:41We will be trying to continue on that theme
- 47:44and look forward to the future
- 47:45conversations. Thank you everybody.
- 47:46Thank you so much.