2023
Expert consensus‐based guidance on approaches to opioid management in individuals with advanced cancer‐related pain and nonmedical stimulant use
Jones K, Khodyakov D, Han B, Arnold R, Dao E, Morrison J, Kapo J, Meier D, Paice J, Liebschutz J, Ritchie C, Merlin J, Bulls H. Expert consensus‐based guidance on approaches to opioid management in individuals with advanced cancer‐related pain and nonmedical stimulant use. Cancer 2023, 129: 3978-3986. PMID: 37691479, PMCID: PMC10910244, DOI: 10.1002/cncr.34921.Peer-Reviewed Original ResearchConceptsCancer-related painConsensus-based guidanceStimulant useUncertain appropriatenessOpioid taperingLonger prognosisShort prognosisPalliative careAddiction expertsNonmedical stimulant useRAND/UCLAStimulant use disorderHarm reduction measuresAdvanced cancerPatient prognosisClinical appropriatenessPainUse disordersPrognosisPatientsExpert consensusOpioidsCancerDelphi panelClinicians
2022
Consensus-Based Guidance on Opioid Management in Individuals With Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder
Jones K, Khodyakov D, Arnold R, Bulls H, Dao E, Kapo J, Meier D, Paice J, Liebschutz J, Ritchie C, Merlin J. Consensus-Based Guidance on Opioid Management in Individuals With Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder. JAMA Oncology 2022, 8: 1107-1114. PMID: 35771550, PMCID: PMC9247858, DOI: 10.1001/jamaoncol.2022.2191.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBenzodiazepinesBuprenorphineCancer PainConsensusFemaleHumansMaleMethadoneNaloxoneNeoplasmsOpioid-Related DisordersConceptsOpioid use disorderCancer-related painOpioid misuseUse disordersClinical scenariosUntreated opioid use disorderAddiction medicine specialistsCommon clinical scenariosDelphi panelImportant comorbidityAdvanced cancerPalliative careMAIN OUTCOMEMedicine specialistsAddiction specialistsPatientsLack of consensusPainAddiction cliniciansDisordersQualitative studyParticipantsComorbiditiesMisusePrognosis
2021
Consensus-based approach to managing opioids, including opioid misuse and opioid use disorder, in patients with serious illness: protocol for a modified Delphi process
King C, Arnold R, Dao E, Kapo J, Liebschutz J, Meier D, Paice J, Ritchie C, Czajkowski K, Khodyakov D, Merlin J. Consensus-based approach to managing opioids, including opioid misuse and opioid use disorder, in patients with serious illness: protocol for a modified Delphi process. BMJ Open 2021, 11: e045402. PMID: 34011593, PMCID: PMC8137210, DOI: 10.1136/bmjopen-2020-045402.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidConsensusDelphi TechniqueHumansOpioid-Related DisordersPain ManagementConceptsOpioid use disorderOpioid misuseSerious illnessInstitutional review boardUse disordersBenefits of opioidsOpioid-related harmsPalliative care cliniciansInstitutional Research BoardPittsburgh Institutional Review BoardOpioid therapyPain managementCare cliniciansPalliative careClinical guidanceEthical approvalIllnessReview boardCliniciansDelphi processPatient casesImplementation toolkitRound 1OpioidsFinal consensus
2020
Patterns of Opioid Prescribing among Medicare Advantage Beneficiaries with Pain and Cardiopulmonary Conditions
Feder SL, Canavan ME, Wang S, Kent EE, Kapo J, Presley CJ, Ross J, Davidoff AJ. Patterns of Opioid Prescribing among Medicare Advantage Beneficiaries with Pain and Cardiopulmonary Conditions. Journal Of Palliative Medicine 2020, 24: 195-204. PMID: 32673139, PMCID: PMC7840305, DOI: 10.1089/jpm.2020.0193.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnalgesics, OpioidHumansMedicare Part CMedicare Part DPainPractice Patterns, Physicians'United StatesConceptsCardiopulmonary conditionsOpioid useMedicare Part D prescription claimsPatterns of opioidSevere pain interferenceUse of opioidsInitiation of opioidsMedicare Advantage beneficiariesNon-Hispanic blacksSelf-reported historyNon-Hispanic whitesOpioid prescribingSevere painNoncancer conditionsPain assessmentPain interferencePrescription claimsAdjusted proportionObservational studyPainPatientsOpioidsLogistic regressionOne-yearCancer
2019
Patterns of pain medication use associated with reported pain interference in older adults with and without cancer
Davidoff AJ, Canavan ME, Feder S, Wang S, Sheinfeld E, Kent EE, Kapo J, Presley CJ. Patterns of pain medication use associated with reported pain interference in older adults with and without cancer. Supportive Care In Cancer 2019, 28: 3061-3072. PMID: 31637515, PMCID: PMC7338979, DOI: 10.1007/s00520-019-05074-8.Peer-Reviewed Original ResearchConceptsSevere pain interferencePrescription pain medicationPain interferencePain medicationOlder adultsMedication receiptMedicare Part D prescription claimsNon-steroidal anti-inflammatory drugsModerate pain interferenceReceipt of opioidsPain medication useManagement of painHalf of adultsAnti-inflammatory drugsPart D low-income subsidyLow-income subsidyOpioid prescribingOpioid prescriptionsSevere painMedication usePain managementSurveillance EpidemiologyPrescription claimsCancer historyChronic conditions
2018
Managing Chronic Pain in Cancer Survivors Prescribed Long-Term Opioid Therapy: A National Survey of Ambulatory Palliative Care Providers
Merlin JS, Patel K, Thompson N, Kapo J, Keefe F, Liebschutz J, Paice J, Somers T, Starrels J, Childers J, Schenker Y, Ritchie CS. Managing Chronic Pain in Cancer Survivors Prescribed Long-Term Opioid Therapy: A National Survey of Ambulatory Palliative Care Providers. Journal Of Pain And Symptom Management 2018, 57: 20-27. PMID: 30342243, DOI: 10.1016/j.jpainsymman.2018.10.493.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyOpioid misuse behaviorsChronic painPalliative care providersCancer survivorsOpioid therapyCare providersAmbulatory palliative care settingAddiction treatmentOpioid treatment agreementsPalliative care settingCare providers' experiencesUrine drug testingMisuse behaviorsPalliative care organizationsPharmacologic treatmentTreatment agreementsCare settingsNurse practitionersPainProvider experienceSurvivorsDrug testingCare organizationsTherapy