2020
Water and lipid suppression techniques for advanced 1H MRS and MRSI of the human brain: Experts' consensus recommendations
Tkáč I, Deelchand D, Dreher W, Hetherington H, Kreis R, Kumaragamage C, Považan M, Spielman DM, Strasser B, de Graaf R. Water and lipid suppression techniques for advanced 1H MRS and MRSI of the human brain: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4459. PMID: 33327042, PMCID: PMC8569948, DOI: 10.1002/nbm.4459.Peer-Reviewed Original ResearchMeSH KeywordsBrainConsensusExpert TestimonyHumansLipidsMagnetic Resonance ImagingMetabolomeProton Magnetic Resonance SpectroscopyRadio WavesSignal Processing, Computer-AssistedWaterContribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations
Cudalbu C, Behar KL, Bhattacharyya PK, Bogner W, Borbath T, de Graaf R, Gruetter R, Henning A, Juchem C, Kreis R, Lee P, Lei H, Marjańska M, Mekle R, Murali‐Manohar S, Považan M, Rackayová V, Simicic D, Slotboom J, Soher BJ, Starčuk Z, Starčuková J, Tkáč I, Williams S, Wilson M, Wright AM, Xin L, Mlynárik V. Contribution of macromolecules to brain 1H MR spectra: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4393. PMID: 33236818, PMCID: PMC10072289, DOI: 10.1002/nbm.4393.Peer-Reviewed Original ResearchSpectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations
Choi I, Andronesi O, Barker P, Bogner W, Edden R, Kaiser L, Lee P, Marjańska M, Terpstra M, de Graaf R. Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4411. PMID: 32946145, PMCID: PMC8557623, DOI: 10.1002/nbm.4411.Peer-Reviewed Original ResearchMeSH KeywordsCalibrationConsensusExpert TestimonyGliomaHumansIsocitrate DehydrogenaseMetabolomeMotor CortexMutationOccipital LobeProton Magnetic Resonance SpectroscopyConceptsSpectral editingIn vivo<sup>1</sup>H MRS, paMulticenter clinical trialSpectral fittingExpert consensus recommendationsD-2-hydroxyglutarateJ-couplingG-aminobutyric acidH-MRSFrequency driftClinical trialsSignal overlapConsensus recommendationsMagnetic resonance spectroscopyMetabolite signalsResonance spectroscopyResonanceExpert recommendationsSequence parameters
2018
Elliptical localization with pulsed second‐order fields (ECLIPSE) for robust lipid suppression in proton MRSI
de Graaf R, Brown PB, De Feyter HM, McIntyre S, Nixon TW. Elliptical localization with pulsed second‐order fields (ECLIPSE) for robust lipid suppression in proton MRSI. NMR In Biomedicine 2018, 31: e3949. PMID: 29985532, PMCID: PMC6108906, DOI: 10.1002/nbm.3949.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrainHumansLipidsMagnetic Resonance ImagingPhantoms, ImagingProton Magnetic Resonance Spectroscopy
2017
Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing
Lindeboom L, de Graaf R. Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing. Magnetic Resonance In Medicine 2017, 79: 619-627. PMID: 28474367, DOI: 10.1002/mrm.26740.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAdultAlgorithmsHumansLipidsMaleMiddle AgedMuscle, SkeletalPhantoms, ImagingProton Magnetic Resonance SpectroscopyConceptsAdipose tissueProton magnetic resonance spectroscopySkeletal muscleH-MRSAccumulation of triglyceridesInvasive biopsyMetabolic derangementsEctopic fatInsulin resistanceCardiovascular diseaseMetabolic diseasesMEGA-sLASER sequenceIn vivoNonadipose tissuesLipid resonancesSpectral editingPolyunsaturated fatty acidsHuman skeletal muscleMagnetic resonance spectroscopyLipid storesLipid compositionAdiposeSpectral resolutionTissuePhantom experiments
2014
Detection of cerebral NAD+ by in vivo 1H NMR spectroscopy
de Graaf R, Behar KL. Detection of cerebral NAD+ by in vivo 1H NMR spectroscopy. NMR In Biomedicine 2014, 27: 802-809. PMID: 24831866, PMCID: PMC4459131, DOI: 10.1002/nbm.3121.Peer-Reviewed Original Research