2006
NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices
Sanganahalli B, Joshi P, Joshi N. NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices. Neurochemistry International 2006, 49: 475-480. PMID: 16860439, DOI: 10.1016/j.neuint.2006.03.006.Peer-Reviewed Original ResearchConceptsNon-NMDA receptorsAdult slicesReactive oxygen species formationNon-NMDAReactive oxygen speciesReceptor stimulationGlutamate receptorsNeuronal cell deathGlutamate-induced neuronal injuryGlutamate mediated neurotoxicityGlutamate receptor agonist NMDACell deathInflux of Ca(2+Mitochondrial depolarizationReceptor agonist NMDAFormation of reactive oxygen speciesNMDA receptor stimulationTreatment of slicesAge groupsAntagonist APVAgonist NMDAYoung slicesCortical slicesNMDA stimulationKA stimulation
2000
Differential effects of tricyclic antidepressant drugs on membrane dynamics—a fluorescence spectroscopic study
Sanganahalli B, Joshi P, Joshi N. Differential effects of tricyclic antidepressant drugs on membrane dynamics—a fluorescence spectroscopic study. Life Sciences 2000, 68: 81-90. PMID: 11132248, DOI: 10.1016/s0024-3205(00)00918-8.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntidepressive Agents, TricyclicCell MembraneKineticsLipid BilayersMaleRatsRats, Sprague-DawleySodium-Potassium-Exchanging ATPaseSpectrometry, FluorescenceSynaptosomesConceptsDimyristoyl phosphatidyl cholineSteady state anisotropyAntidepressant drugsTime-dependent anisotropyDecay of anisotropyFluorescence decay timeSynaptosomal membranesActivity of Na+-K+-ATPaseTricyclic antidepressant drugsNa+-K+-ATPaseDecay timeAntidepressant drug amitriptylineNortriptyline treatmentLimiting anisotropyRat brain synaptosomesTricyclic antidepressant drug amitriptylineDesipramineAmitriptylineCase of amitriptylineImipramineNortriptylineRat brainAnisotropyBrain synaptosomesTime-dependent fluorescence spectroscopy