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Phase I

Study of CD19-targeted NEX-T CAR T Cells in Participants with Relapsing Forms of Multiple Sclerosis (RMS) or Progressive Forms of Multiple Sclerosis (PMS)

What is the purpose of this trial?

We are looking for people 18 to 50 years old with a diagnosis of relapsing multiple sclerosis (RMS), including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS), as well as those 18 to 60 with a diagnosis of progressive multiple sclerosis (PMS), including primary progressive MS (PPMS) and/or inactive SPMS, to take part in a clinical research study.

Participants will receive the investigational therapy, study-related medical exams, and study-related laboratory tests at no cost. Reimbursement for travel and other out-of-pocket expenses will be available in addition to possible compensation for time.

To learn more and see if you may qualify, visit BMSStudyConnect.com/MSCARTpatient.

Contact Information

For more information about this study, including how to volunteer, contact Bailey Sheldon

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877.978.8343 for more information.

  • Last Updated
    11/08/2025
  • Study HIC
    #2000037550