Wei Wei, PhD
Assistant Professor of Medicine (Medical Oncology)DownloadHi-Res Photo
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Appointments
Medical Oncology and Hematology
Primary
Additional Titles
Interim Director of Biostatistics Shared Resource, Yale Cancer Center
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Appointments
Medical Oncology and Hematology
Primary
Additional Titles
Interim Director of Biostatistics Shared Resource, Yale Cancer Center
Contact Info
Appointments
Medical Oncology and Hematology
Primary
Additional Titles
Interim Director of Biostatistics Shared Resource, Yale Cancer Center
Contact Info
About
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Titles
Assistant Professor of Medicine (Medical Oncology)
Interim Director of Biostatistics Shared Resource, Yale Cancer Center
Biography
Wei Wei is an Associate Professor at Yale School of Medicine and Director of the Biostatistics Shared Resource at Yale Cancer Center. Dr. Wei's research area focuses on development of early phase clinical trial designs, with particular interest in cancer targeted and immunotherapeutic agents.
Last Updated on January 07, 2026.
Appointments
Medical Oncology and Hematology
Assistant ProfessorPrimary
Other Departments & Organizations
- All Institutions
- Internal Medicine
- Medical Oncology and Hematology
- Yale Cancer Center
Education & Training
- PhD
- Medical University of South Carolina, Biostatistics (2016)
Research
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Overview
Public Health Interests
Clinical Trials; Cancer; Biomarkers
ORCID
0000-0003-1263-5620
Research at a Glance
Yale Co-Authors
Frequent collaborators of Wei Wei's published research.
Harriet Kluger, MD
David Rimm, MD, PhD
Daniel Zelterman, PhD
Amit Mahajan, MD, MBBS
Jan Philipp Bewersdorf, MD, FACP
Michael Kane, PhD, MA, MS
Publications
2026
Change-Point Homogeneity in Piecewise Exponential Survival
Yu C, Wei W, Zelterman D. Change-Point Homogeneity in Piecewise Exponential Survival. Journal Of Statistical Theory And Practice 2026, 20: 32. DOI: 10.1007/s42519-026-00551-w.Peer-Reviewed Original ResearchConceptsChange-pointsIndividual survival timesLikelihood ratio testHazard functionExponential distributionGraphical diagnosticsFailure timeExponential survivalNull hypothesisRatio testDensity functionLow risk of disease progressionSurvival timeRisk of disease progressionLow riskDatabase of womenPiecewiseBreast cancerDisease progressionRenal patientsCurrent Management Practices of De Novo Oligometastatic Breast Cancer: Real-World Data From a Physician Survey.
Odzer N, Wei W, Lustberg M, Pusztai L, Rozenblit M. Current Management Practices of De Novo Oligometastatic Breast Cancer: Real-World Data From a Physician Survey. JCO Oncology Practice 2026, op2500413. PMID: 41616223, DOI: 10.1200/op-25-00413.Peer-Reviewed Original ResearchAltmetricConceptsOligometastatic breast cancerMetastatic breast cancerBreast cancerMedical oncologistsSurgical resectionAblative radiationHuman epidermal growth factor receptor 2-positiveEpidermal growth factor receptor 2-positiveResponse to initial chemotherapyOptimal managementPractice patternsHER2+ diseaseTriple-negative diseasePalliative systemic chemotherapyPrimary breast tumorsCurative-intent therapyTreatment of de novoManagement of de novoUS medical oncologistsSystemic chemotherapyReceptor-positiveInitial chemotherapyPrimary tumorResidual lesionsReceptor subtypesBayesian randomized basket trial design: a case study from the ultra-rare invasive mold infections
Liu Y, Roychoudhury S, Wei W. Bayesian randomized basket trial design: a case study from the ultra-rare invasive mold infections. Biometrics 2026, 82: ujag001. PMID: 41608839, DOI: 10.1093/biomtc/ujag001.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and Concepts
2025
Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas
Cheung J, Hunt B, Wahed S, Cheng E, Connolly K, Venkatesan S, Loza J, Bansal I, Fagerberg E, Kessler E, Riffard C, Buck J, Attanasio J, Borr E, Wei W, William I, Fitzgerald B, Joshi N. Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas. Cancer Cell 2025, 43: 2311-2326.e4. PMID: 41043437, PMCID: PMC12693725, DOI: 10.1016/j.ccell.2025.09.005.Peer-Reviewed Original ResearchAltmetricThe Maximum Negative Hypergeometric Distribution
Yu C, Prishwalko K, Blaha O, Kane M, Wei W, Esserman D, Zelterman D. The Maximum Negative Hypergeometric Distribution. Journal Of Statistical Theory And Practice 2025, 19: 88. DOI: 10.1007/s42519-025-00502-x.Peer-Reviewed Original ResearchFruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO
Dasari A, Eng C, Lonardi S, Garcia-Carbonero R, Masuishi T, Cremolini C, Ghiringhelli F, Hubbard J, Bekaii-Saab T, Jones J, Xu R, Shen L, Xu J, Bai Y, Deng Y, Yuan Y, Wei W, Lin J, Chen L, Yang Z, Schelman W, Qin S, Li J. Fruquintinib in less pretreated patients: Multivariate profile-matching analysis of FRESCO-2 to FRESCO. European Journal Of Cancer 2025, 227: 115641. PMID: 40795524, DOI: 10.1016/j.ejca.2025.115641.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsProgression-free survivalMetastatic colorectal cancerITT populationOverall survivalIntention-to-treatEastern Cooperative Oncology Group performance statusPretreated metastatic colorectal cancerTreatment-emergent adverse eventsTreatment linesEfficacy of fruquintinibPrior treatment linesSafety of fruquintinibGlobal patient populationUnstratified hazard ratioPretreated patientsMetastatic sitesRAS statusLiver metastasesPerformance statusBaseline characteristicsAdverse eventsFruquintinibColorectal cancerPatient populationHazard ratioClinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer
Ajjawi I, Rios A, Wei W, Park TS, Lustberg MB. Clinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer. Breast Cancer Res Treat. 2025 Jul;212(2):299-308. doi: 10.1007/s10549-025-07725-3. Epub 2025 May 15. PMID: 40369346.Peer-Reviewed Original ResearchClinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer
Ajjawi I, Rios A, Wei W, Park T, Lustberg M. Clinical, sociodemographic, and facility-related determinants of immunotherapy use in metastatic triple-negative breast cancer. Breast Cancer Research And Treatment 2025, 212: 299-308. PMID: 40369346, DOI: 10.1007/s10549-025-07725-3.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsMetastatic triple-negative breast cancerMetastatic triple-negative breast cancer patientsNational Cancer DatabaseTriple-negative breast cancerImmunotherapy useRetrospective cohort studyBreast cancerLog-rank testCox proportional hazards regressionHigher Charlson comorbidity scoreCharlson comorbidity scoreMultivariate logistic regressionProportional hazards regressionLow likelihoodOverall survivalCancer DatabaseImmunotherapy recipientsSurvival outcomesImmunotherapyDiagnosis yearComorbidity scoreBlack raceHazards regressionPatientsHispanic ethnicityClinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer
Ajjawi I, Rios A, Wei W, Park TS, Lustberg MB. Clinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer. Cancers (Basel). 2025 May 6;17(9):1579. doi: 10.3390/cancers17091579. PMID: 40361505; PMCID: PMC12072055.Peer-Reviewed Original ResearchClinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer
Ajjawi I, Rios A, Wei W, Park T, Lustberg M. Clinical, Sociodemographic, and Facility-Related Factors Influencing HER2-Targeted Therapy in Metastatic Hormone Receptor-Negative, HER2-Positive Breast Cancer. Cancers 2025, 17: 1579. PMID: 40361505, PMCID: PMC12072055, DOI: 10.3390/cancers17091579.Peer-Reviewed Original ResearchAltmetricConceptsHER2-Targeted TherapyHormone receptor-negativeRetrospective cohort studyBreast cancer patientsTherapy useBreast cancerHER2-positiveReceptor-negativeSurvival outcomesCancer patientsHER2-positive breast cancerTherapy utilizationLog-rank testCox proportional hazards regressionFacility-related barriersMultivariate logistic regressionProportional hazards regressionHR-/HER2Overall survivalTherapy recipientsLower mortality riskHER2 targetingBlack raceHazards regressionMedicare insurance
Academic Achievements & Community Involvement
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Activities
activity Leukemia & Lymphoma Society
2025 - PresentPeer Review Groups and Grant Study SectionsGrant Revieweractivity Design and Implementation of Clinical Trials
11/17/2025 - 11/21/2025LectureWinn-AACR Design and Implementation of Clinical Trials WorkshopDetailsAlbuquerque, NM, United StatesSponsored by American Association for Cancer ResearchCollaborators
Teaching & Mentoring
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Mentoring
Jinping Liang
Graduate student2025 - PresentMichelle Song
Graduate student2025 - PresentYunhe Liu
Graduate student at YSPH2022 - 2024Yunxuan Zhang
Graduate student at YSPH2022 - 2023
Willing and Available to Mentor
- Faculty
- Students
- Residents
- Postdoctoral Researchers
- Clinical Fellows
- Clinicians
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