Timur Yarovinsky, MD, PhD
Research Scientist (Cardiovascular Medicine)Cards
About
Research
Publications
2026
X-inactive specific transcript (XIST) can determine sex differences in cardiovascular drug responses: focus on RNA therapeutics
Yarovinsky T, Ramgolam V, Knezevic I, Stachenfeld N, Bender J. X-inactive specific transcript (XIST) can determine sex differences in cardiovascular drug responses: focus on RNA therapeutics. Frontiers In Pharmacology 2026, 16: 1716863. PMID: 41601966, PMCID: PMC12832541, DOI: 10.3389/fphar.2025.1716863.Peer-Reviewed Original Research
2025
Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling
Kim S, Nouws J, Ruwisch J, Woodard G, Cooley J, Khoury J, Sun H, Doherty E, Piecychna M, Manning E, Kang M, Bruscia E, Wei H, Zhang Y, Yarovinsky T, Hwa J, Zacharias W, Ingram J, Lee C, Elias J, Kaminski N, Redente E, Herzog E, Prasse A, Bucala R, Sauler M. Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling. Science Translational Medicine 2025, 17: eadr2277. PMID: 41337540, DOI: 10.1126/scitranslmed.adr2277.Peer-Reviewed Original ResearchAlveolar Epithelial CellsAnimalsAntigens, Differentiation, B-LymphocyteBleomycinDisease Models, AnimalHistocompatibility Antigens Class IIHumansIdiopathic Pulmonary FibrosisIntramolecular OxidoreductasesLungMacrophage Migration-Inhibitory FactorsMacrophagesMaleMiceMice, Inbred C57BLMice, TransgenicProteasome Endopeptidase ComplexProteostasisSignal TransductionUbiquitinImmunization with virus-like vesicle-based COVID-19 vaccine induces robust systemic and mucosal immunity
Yang L, Yarovinsky T, Pham K, Xi Y, Lu P, Iwasaki A, Rose J, Liu C. Immunization with virus-like vesicle-based COVID-19 vaccine induces robust systemic and mucosal immunity. Npj Vaccines 2025, 10: 211. PMID: 41022870, PMCID: PMC12480480, DOI: 10.1038/s41541-025-01260-4.Peer-Reviewed Original ResearchEROdicating arterial thrombosis with a novel endoplasmic reticulum oxidoreductase 1α inhibitor
Yarovinsky T, Sharda A, Hwa J. EROdicating arterial thrombosis with a novel endoplasmic reticulum oxidoreductase 1α inhibitor. Molecular Therapy 2025, 33: 4682-4683. PMID: 40975058, PMCID: PMC12848167, DOI: 10.1016/j.ymthe.2025.09.012.Peer-Reviewed Original ResearchCARG-2020 targets IL-12, IL-17, and PD-L1 pathways to effectively treat melanoma and breast cancer
Ahmadi E, Chiari C, Madina B, Yarovinsky T, Krady M, Chen J, Almassian B, Nakaar V, Wang K. CARG-2020 targets IL-12, IL-17, and PD-L1 pathways to effectively treat melanoma and breast cancer. Scientific Reports 2025, 15: 29649. PMID: 40804279, PMCID: PMC12350727, DOI: 10.1038/s41598-025-14750-1.Peer-Reviewed Original ResearchEnhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation
Amoako K, Mokhammad A, Malik A, Yesudasan S, Wheba A, Olagunju O, Gu S, Yarovinsky T, Faustino E, Nguyen J, Hwa J. Enhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation. Frontiers In Medical Technology 2025, 7: 1591119. PMID: 40589473, PMCID: PMC12206802, DOI: 10.3389/fmedt.2025.1591119.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPlatelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease (Adv. Sci. 5/2025)
Zhang Y, Jia C, Guo M, Chen Q, Wen Y, Wang T, Xie Y, Fan X, Gao J, Yarovinsky T, Liu R, Jiang Z, Wang M, Zhou J, Che D, Fu L, Edelson R, Gu X, Hwa J, Tang W. Platelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease (Adv. Sci. 5/2025). Advanced Science 2025, 12: 2570027. PMCID: PMC11791971, DOI: 10.1002/advs.202570027.Peer-Reviewed Original Research
2024
Platelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease
Zhang Y, Jia C, Guo M, Chen Q, Wen Y, Wang T, Xie Y, Fan X, Gao J, Yarovinsky T, Liu R, Jiang Z, Wang M, Zhou J, Che D, Fu L, Edelson R, Gu X, Hwa J, Tang W. Platelet–Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease. Advanced Science 2024, 12: 2406282. PMID: 39665236, PMCID: PMC11792051, DOI: 10.1002/advs.202406282.Peer-Reviewed Original ResearchPlatelet Mitochondrial Fusion and Function in Vascular Integrity
Tyagi T, Yarovinsky T, Faustino E, Hwa J. Platelet Mitochondrial Fusion and Function in Vascular Integrity. Circulation Research 2024, 134: 162-164. PMID: 38236952, PMCID: PMC10798220, DOI: 10.1161/circresaha.123.323867.Commentaries, Editorials and Letters
2023
Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory
Alvero A, Fox A, Madina B, Krady M, Gogoi R, Chehade H, Nakaar V, Almassian B, Yarovinsky T, Rutherford T, Mor G. Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory. Cancer Immunology Research 2023, 12: 261-274. PMID: 38078853, PMCID: PMC11027955, DOI: 10.1158/2326-6066.cir-23-0127.Peer-Reviewed Original Research