Sinan Guloksuz, MD, PhD

2026

• Association between menstrual cycle characteristics and mental health in early adolescence

  Marla S, Gangaraju S, Nguyen J, Sarasjärvi K, Ye R, Schmaal L, Thompson A, Clark S, Lin A, Wigman J, Wood S, Davey C, Guloksuz S, Nelson B, Middeldorp C, Byrne E. Association between menstrual cycle characteristics and mental health in early adolescence. European Child & Adolescent Psychiatry 2026, 1-15. PMID: 42622878, DOI: 10.1007/s00787-026-03163-8.

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• Associations between lifestyle, genetic liability for severe mental illness and risk of incident somatic illnesses

  Isayeva U, Guloksuz S, Lin B, de Boer N, Rutten B, Linden D, Manchia M, Luykx J. Associations between lifestyle, genetic liability for severe mental illness and risk of incident somatic illnesses. Translational Psychiatry 2026 DOI: 10.1038/s41398-026-04332-8.

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• Polygenic liability to loneliness increases psychosis risk through adolescent loneliness: evidence from the EU-GEI study

  González-Peñas J, Andreu-Bernabeu Á, Mora A, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, García-Portilla M, Sanjuan J, Santos J, Jiménez-López E, Arrojo M, Carracedo A, López G, Parellada M, van Os J, Delespaul P, Rutten B, Pries L, Guloksuz S, Murray R, Di Forti M, Vassos E, Maric N, Atbaşoğlu C, Saka M, Üçok A, Alptekin K, Arango C, Díaz-Caneja C. Polygenic liability to loneliness increases psychosis risk through adolescent loneliness: evidence from the EU-GEI study. Schizophrenia 2026 DOI: 10.1038/s41537-026-00787-2.

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• Developmental Trauma as a Prognostic Factor for Later Psychotic Disorder in an Adolescent Clinical Cohort: A 20‐Year Follow Up Study

  Kieseppä V, Díaz‐Caneja C, Rutten B, Riipinen P, Gülöksüz S, Kelleher I. Developmental Trauma as a Prognostic Factor for Later Psychotic Disorder in an Adolescent Clinical Cohort: A 20‐Year Follow Up Study. Acta Psychiatrica Scandinavica 2026 PMID: 42386520, DOI: 10.1111/acps.70122.

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• Mental healthcare expenditure in the Netherlands by urbanicity and neighbourhood socioeconomic status and interactions with age over the period 2015–2020

  Dijkstra L, Gülöksüz S, Batalla A, van Os J. Mental healthcare expenditure in the Netherlands by urbanicity and neighbourhood socioeconomic status and interactions with age over the period 2015–2020. Archives Of Public Health 2026 PMID: 42374589, DOI: 10.1186/s13690-026-01991-3.

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• Co-expression-based models improve eQTL predictions for transcriptome-wide association studies and highlight new schizophrenia-associated genes

  Rossi F, Sportelli L, Kikidis G, Grassi G, Di Camillo F, Bertolino A, Blasi G, Borcuk C, Fusco D, Hyde T, Kleinman J, Marnetto D, Pellegrini S, Rampino A, Vitiello B, Ripke S, Braun A, Kraft J, Belangero S, Menezes P, Arango C, Walters J, O’Donovan M, Owen M, Braff D, Corvin A, Morris D, Domenici E, van Os J, Atbaşoğlu E, Saka M, Di Forti M, Baune B, Pato C, McQuillin A, Golimbet V, Kondratyev N, Escott-Price V, Gareeva A, Khusnutdinova E, Cervilla J, Rivera M, Campion D, Laurent-Levinson C, Serretti A, Andreassen O, St. Clair D, Lencz T, Malhotra A, McCarthy N, Mowry B, Rujescu D, Giegling I, Hartmann A, Konte B, Nöthen M, Rietschel M, Kirov G, Sullivan P, Petryshen T, Werge T, McIntosh A, Esko T, Jönsson E, Ehrenreich H, Riley B, Levinson D, Buxbaum J, Bramon E, Hultman C, Ophoff R, Adolfsson R, Stahl E, Guloksuz S, Rutten B, Del-Ben C, Thibaut F, Weinberger D, Pergola G. Co-expression-based models improve eQTL predictions for transcriptome-wide association studies and highlight new schizophrenia-associated genes. Nature Genetics 2026, 58: 1559-1572. PMID: 42332269, PMCID: PMC13364706, DOI: 10.1038/s41588-026-02646-3.

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  MeSH Keywords

• Interpersonal stress, epigenetic indices of inflammation, and depressive symptoms: Longitudinal associations from adolescence to young adulthood

  Mastrotheodoros S, Schalkwijk W, de Groot M, Gülöksüz S, Nelemans S, van Os J, Rutten B, Meeus W, Boks M, Branje S. Interpersonal stress, epigenetic indices of inflammation, and depressive symptoms: Longitudinal associations from adolescence to young adulthood. Neurobiology Of Stress 2026, 43: 100832. PMID: 42388421, PMCID: PMC13320348, DOI: 10.1016/j.ynstr.2026.100832.

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• Shared genetic architecture between Alzheimer’s disease and brain morphology

  Wu X, Shadrin A, Blokland G, Guloksuz S, Andreassen O, Linden D, van der Meer D. Shared genetic architecture between Alzheimer’s disease and brain morphology. Alzheimer's Research & Therapy 2026, 18: 188. PMID: 42271432, PMCID: PMC13483600, DOI: 10.1186/s13195-026-02105-5.

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• Quality over quantity: association between autistic traits and daily-life social interactions in adolescents and young adults from the TwinssCan cohort

  Fusar-Poli L, Prachason T, Brondino N, Nola M, Lin B, Pries L, Doğan M, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, van Os J, Rutten B, Politi P, Guloksuz S. Quality over quantity: association between autistic traits and daily-life social interactions in adolescents and young adults from the TwinssCan cohort. CNS Spectrums 2026, 31: e14. PMID: 42223028, DOI: 10.1017/s1092852926100947.

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  MeSH Keywords

• Psychotropic medication use, lifestyle, genetic risk for high BMI and the incidence of cardiovascular disease

  de Boer N, Hanskamp I, Lin B, Boonstra L, van der Horst M, van Eijk K, Boks M, Peyrot W, Twisk J, Goldschmidt T, Pijl H, Vinkers C, Correll C, De Hert M, Guloksuz S, Cahn W, Luykx J. Psychotropic medication use, lifestyle, genetic risk for high BMI and the incidence of cardiovascular disease. Nature Mental Health 2026, 4: 766-774. DOI: 10.1038/s44220-026-00620-w.

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