Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsMaor Sauler, MD
Associate Professor AdjunctAbout
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Titles
Associate Professor Adjunct
Biography
Maor Sauler has been a member of the Pulmonary & Critical Care faculty since 2014. Dr. Sauler specializes in adult critical care including acute lung injury and sepsis. He also sees patients in the outpatient setting with pulmonary diseases such as Chronic Obstructive Pulmonary Disease (COPD). Dr. Sauler is board-certified in internal medicine, pulmonary medicine, and critical care medicine.
Dr. Sauler earned his undergraduate degree from Princeton University and received his MD from Rutgers-New Jersey Medical School. Dr. Sauler then completed both an internship and residency in internal medicine at Yale-New Haven Hospital. He went on to complete fellowship training in pulmonary and critical care medicine at Yale-School of Medicine.
Dr. Sauler investigates mechanisms of lung injury and cytoprotection by integrating findings from high-throughput sequencing technologies with murine and in vitro models of chronic lung disease. Specifically, he is focused on identifying cellular stress responses that change with age or with COPD, and understanding how these mechanisms contribute to disease susceptibility or maintain lung "resilience". By studying the impact of aberrant cellular stress responses on lung injury, inflammation, and repair, Dr. Sauler hopes to identify novel therapeutic targets for patients with COPD.
Appointments
Pulmonary, Critical Care & Sleep Medicine
Associate Professor AdjunctPrimary
Other Departments & Organizations
- CPIRT - Center for Pulmonary Injury, Repair, and Therapeutics
- Internal Medicine
- Kaminski Lab
- Pulmonary, Critical Care & Sleep Medicine
- The Center for Precision Pulmonary Medicine (P2MED)
- Winchester Center for Lung Disease
Education & Training
- Fellow
- Yale School of Medicine (2014)
- Resident
- Yale-New Haven Hospital (2009)
- Intern
- Yale-New Haven Hospital (2007)
- MD
- Rutgers New Jersey Medical School (2006)
- BA
- Princeton University (2001)
Research
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Overview
Medical Research Interests
ORCID
0000-0001-5240-7978
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Naftali Kaminski, MD
Jose Gomez Villalobos, MD, MS
Xiting Yan, PhD
Yu Zhang, MD, PhD
Clemente Britto-Leon, MD
Edward Manning, MD, PhD
Aging
Emphysema
Lung Diseases
Respiratory Distress Syndrome
Lung Injury
Publications
Featured Publications
Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease
Sauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R, Lee PJ. Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2014, 306: l487-l496. PMID: 24441872, PMCID: PMC3949087, DOI: 10.1152/ajplung.00284.2013.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAnimalsApoptosisCellular SenescenceCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p21EmphysemaFemaleHumansIntramolecular OxidoreductasesLungMacrophage Migration-Inhibitory FactorsMaleMiceMice, Inbred C57BLMice, KnockoutMiddle AgedNicotianaPulmonary Disease, Chronic ObstructiveReceptors, ImmunologicSmokeSmokingTumor Suppressor Protein p53Young AdultEndothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury
Sauler M, Zhang Y, Min J, Leng L, Shan P, Roberts S, Jorgensen WL, Bucala R, Lee PJ. Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury. The FASEB Journal 2015, 29: 1940-1949. PMID: 25609432, PMCID: PMC4415022, DOI: 10.1096/fj.14-260299.Peer-Reviewed Original ResearchCitationsAltmetricThe DNA repair transcriptome in severe COPD
Sauler M, Lamontagne M, Finnemore E, Herazo-Maya JD, Tedrow J, Zhang X, Morneau JE, Sciurba F, Timens W, Paré PD, Lee PJ, Kaminski N, Bossé Y, Gomez JL. The DNA repair transcriptome in severe COPD. European Respiratory Journal 2018, 52: 1701994. PMID: 30190272, PMCID: PMC6422831, DOI: 10.1183/13993003.01994-2017.Peer-Reviewed Original ResearchCitationsAltmetricMicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease
Nouws J, Wan F, Finnemore E, Roque W, Kim SJ, Bazan IS, Li CX, Sköld C, Dai Q, Yan X, Chioccioli M, Neumeister V, Britto CJ, Sweasy J, Bindra RS, Wheelock ÅM, Gomez JL, Kaminski N, Lee PJ, Sauler M. MicroRNA miR-24-3p reduces DNA damage responses, apoptosis, and susceptibility to chronic obstructive pulmonary disease. JCI Insight 2021, 6: e134218. PMID: 33290275, PMCID: PMC7934877, DOI: 10.1172/jci.insight.134218.Peer-Reviewed Original ResearchCitationsAltmetricCharacterization of the COPD alveolar niche using single-cell RNA sequencing
Sauler M, McDonough JE, Adams TS, Kothapalli N, Barnthaler T, Werder RB, Schupp JC, Nouws J, Robertson MJ, Coarfa C, Yang T, Chioccioli M, Omote N, Cosme C, Poli S, Ayaub EA, Chu SG, Jensen KH, Gomez JL, Britto CJ, Raredon MSB, Niklason LE, Wilson AA, Timshel PN, Kaminski N, Rosas IO. Characterization of the COPD alveolar niche using single-cell RNA sequencing. Nature Communications 2022, 13: 494. PMID: 35078977, PMCID: PMC8789871, DOI: 10.1038/s41467-022-28062-9.Peer-Reviewed Original ResearchCitationsAltmetricCell Death in the Lung: The Apoptosis–Necroptosis Axis
Sauler M, Bazan IS, Lee PJ. Cell Death in the Lung: The Apoptosis–Necroptosis Axis. Annual Review Of Physiology 2018, 81: 1-28. PMID: 30485762, PMCID: PMC6598441, DOI: 10.1146/annurev-physiol-020518-114320.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricA functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity
Zhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis K, Song Y, Michael H, McCormack M, Allore H, Morris A, Crothers K, Bucala R, Lee P, Sauler M. A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 316: l400-l405. PMID: 30520689, PMCID: PMC6397351, DOI: 10.1152/ajplung.00439.2018.Peer-Reviewed Original ResearchCitationsAltmetric
2026
Origin, Niche, and State: A Three-Body Problem in Lung Macrophage Biology
Sauler M, Curtis J. Origin, Niche, and State: A Three-Body Problem in Lung Macrophage Biology. American Journal Of Respiratory And Critical Care Medicine 2026, aamag273. PMID: 42236266, DOI: 10.1093/ajrccm/aamag273.Peer-Reviewed Original ResearchHHIP’s dynamic role in epithelial wound healing reveals a potential mechanism of COPD susceptibility
Deritei D, Anamika W, Zhou A, Yun J, Sauler M, Cho M, Silverman E, Regan E, Glass K. HHIP’s dynamic role in epithelial wound healing reveals a potential mechanism of COPD susceptibility. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2424377123. PMID: 42190016, PMCID: PMC13225619, DOI: 10.1073/pnas.2424377123.Peer-Reviewed Original ResearchAltmetricIntegrated molecular networks reveal latent components distinguishing type 2-high and type 2-low asthma
Ramirez M, Diaz M, Wang N, Liu Q, Li H, Kay S, Shuguli M, Zielonka J, Wilson G, Sauler M, Wang Z, Yan X, Chupp G, Gomez J. Integrated molecular networks reveal latent components distinguishing type 2-high and type 2-low asthma. BMJ Open Respiratory Research 2026, 13: e004003. PMID: 42150795, PMCID: PMC13185048, DOI: 10.1136/bmjresp-2025-004003.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
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Honors
honor Rising Star
05/15/2019National AwardAmerican Thoracic SocietyDetailsUnited Stateshonor Pepper Center Scholar Award
04/01/2019Yale School of Medicine AwardYale Pepper CenterDetailsUnited Stateshonor K08 Career Development Award
01/01/2017National AwardNational Institute of Health, NHLBIDetailsUnited Stateshonor Young Clinical Scientist Award
07/01/2015National AwardFlight Attendant Medical Research InstituteDetailsUnited Stateshonor Abstract Scholarship Award
05/15/2015National AwardAmerican Thoracic SocietyDetailsUnited States
News
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News
- January 29, 2026
Zooming In on COPD: A Single-Cell Atlas of the Diseased Lung
- December 08, 2025
New Study Reveals Key Signaling Pathway in Pulmonary Fibrosis
- February 17, 2025Source: Newsweek
Vatican gives latest update on Pope Francis' condition
- July 09, 2024Source: Everyday Health
Can COPD Be Reversed With Exercise?
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