Lauren Pischel, MD, MSc
Assistant Professor of Medicine (Infectious Diseases)DownloadHi-Res Photo
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Affiliated Faculty, Yale Institute for Global Health
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Assistant Professor of Medicine (Infectious Diseases)
Affiliated Faculty, Yale Institute for Global Health
Biography
Dr. Lauren Pischel obtained her undergraduate degree in biology at Brown University and worked in the lab of Dr. Jake Kurtis on the development of a pediatric malaria vaccine. She obtained her MD at Stanford where she conducted research with Dr. Julie Parsonnet on the impact of an antimicrobial triclosan on the human microbiome. She then completed her internal medicine residency at Yale where she was awarded the primary care award for the Fair Haven Community Health Center. She subsequently pursued her fellowship in infectious diseases at Yale and her Master of Science in the epidemiology of infectious diseases at the Yale School of Public Health under the mentorship of Saad Omer and Inci Yildirim. Her research interests include the epidemiology and household transmission of COVID-19 and influenza as well estimating vaccine effectiveness using real-world data and the epidemiology emerging infectious diseases.
Last Updated on April 10, 2025.
Departments & Organizations
- Internal Medicine
- Janeway Society
- Yale Medicine
- Yale New Haven Health System
Education & Training
- MSc
- Yale, Public Health- Epidmiology of Infectious Diseases (2022)
- MD
- Stanford School of Medicine (2016)
- ScB
- Brown University, Biology (2011)
Research
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Overview
Public Health Interests
Climate Change; Emerging Infectious Diseases; Global Health; Vaccines
ORCID
0000-0002-7697-0084
Research at a Glance
Yale Co-Authors
Frequent collaborators of Lauren Pischel's published research.
Publications Timeline
A big-picture view of Lauren Pischel's research output by year.
Inci Yildirim, MD, PhD, MSc
Albert Icksang Ko, MD
Marwan Mikheal Azar, MD, FAST, FIDSA
Richard A Martinello, MD
Carolina Lucas, PhD
M. Catherine Muenker, MS
30Publications
575Citations
Publications
2026
Neutralising antibody responses to MPXV clades Ia, Ib, and IIb after infection or vaccination: a multicountry observational study
Crandell J, Fantin R, de Araújo L, Lawres L, Pischel L, Monteiro V, Conde L, Kottkamp A, Samanovic M, Cordeiro R, Póvoas D, Melo M, Castineiras T, Vale A, Yildirim I, Mulligan M, de Almeida L, Omer S, Coelho C, Lucas C. Neutralising antibody responses to MPXV clades Ia, Ib, and IIb after infection or vaccination: a multicountry observational study. The Lancet Infectious Diseases 2026 PMID: 42314719, DOI: 10.1016/s1473-3099(26)00173-8.Peer-Reviewed Original ResearchCitationsAltmetricConceptsMVA-BNControl cohortVaccinated cohortUS National InstitutesPlasma samplesMonkeypox virusNeutralising activityNo historyVaccina virusObservational studyAntibody-based countermeasuresCross-clade immunityPolyclonal plasma antibodiesSmallpox vaccine DryvaxOutbreak of monkeypox virusMonkeypox virus infectionAntibody bindingVaccine-induced immunityThreshold of positivityMonkeypox virus cladesClade IAPlaque reduction neutralisation testUS National Institutes of HealthAntigen levelsMPXV infectionAir conditioning, ventilation, and respiratory virus transmission potential in South India
Shah P, Pischel L, Sack B, Basith K, Dauphinais M, Jain K, Martins M, Wallace S, Karoly M, Lakshminarayanan S, Cintron C, Subramanian S, Sahay A, Koura K, Brooks R, Shenoi S, Chinnakali P, Sinha P. Air conditioning, ventilation, and respiratory virus transmission potential in South India. International Journal Of Infectious Diseases 2026, 168: 108724. PMID: 42031292, PMCID: PMC13286084, DOI: 10.1016/j.ijid.2026.108724.Peer-Reviewed Original ResearchAltmetricConcepts
2025
Impact of indoor ventilation on TB transmission risk: implications of climate change
Sack B, Shah P, Abdul Basith K, Dauphinais M, Jain K, Martins M, Wallace S, Lakshminarayanan S, Cintron C, Subramanian S, Sahay A, Koura K, Pischel L, Brooks R, Shenoi S, Chinnakali P, Sinha P. Impact of indoor ventilation on TB transmission risk: implications of climate change. The International Journal Of Tuberculosis And Lung Disease 2025, 29: 507-513. PMID: 41666017, DOI: 10.5588/ijtld.25.0129.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsComparable Outcomes in Suspected Septic Shock: A Retrospective Study of Emergency Department Patients With and Without Bacteremia
Belsky J, Wira C, Fryman A, He Z, Boccio E, Haimovich A, Jacob V, Pischel L. Comparable Outcomes in Suspected Septic Shock: A Retrospective Study of Emergency Department Patients With and Without Bacteremia. Journal Of Emergency Medicine 2025, 79: 349-358. PMID: 41175539, PMCID: PMC12911937, DOI: 10.1016/j.jemermed.2025.08.039.Peer-Reviewed Original ResearchAltmetricConceptsEmergency departmentHospital outcomesIntensive care unit lengthPresence of bacteremiaLength of stayED variablesSeptic shockBlood culturesHospital mortalityUrban academic centerRetrospective studyAdult patientsHospital lengthEmergency department patientsIntensive care unit length of stayUnit length of stayGram-negative bacteremiaHospital length of stayInitial blood cultureLogistic regression analysisAssociated with bacteremiaPatient encountersRetrospective observational analysisDepartment patientsSecondary aimSocial mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Zaleski A, Paintsil E, Muenker M, Malik A, Kiti M, Warren J, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. Social mixing patterns of United States healthcare personnel at a quaternary health center: a prospective observational study. Infection Control And Hospital Epidemiology 2025, 46: 289-297. PMID: 39880795, PMCID: PMC11883655, DOI: 10.1017/ice.2024.234.Peer-Reviewed Original ResearchAltmetricConceptsHealthcare personnelUnited States healthcare systemStates healthcare systemCOVID-19 pandemicNurse aidesContact diariesHealth centersHealthcare systemWorking-age populationImaging technologistsLow-contact groupNursesRegression modelsPandemic responseWork environmentSocial contactCOVID-19Job typeThree-hundredWorking daysDiaryParticipantsPersonnelInfectious disease transmissionContact group
2024
Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol
Aguolu O, Kiti M, Nelson K, Liu C, Sundaram M, Gramacho S, Jenness S, Melegaro A, Sacoor C, Bardaji A, Macicame I, Jose A, Cavele N, Amosse F, Uamba M, Jamisse E, Tchavana C, Briones H, Jarquín C, Ajsivinac M, Pischel L, Ahmed N, Mohan V, Srinivasan R, Samuel P, John G, Ellington K, Joaquim O, Zelaya A, Kim S, Chen H, Kazi M, Malik F, Yildirim I, Lopman B, Omer S. Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol. PLOS ONE 2024, 19: e0301638. PMID: 38913670, PMCID: PMC11195963, DOI: 10.1371/journal.pone.0301638.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLow-and-middle-income countriesData collection toolHousehold membersBurden of communicable diseasesCollection toolLow-and-middle-incomeDisease prevention strategiesInteraction dataPatterns of social mixingSocial mixingParameterizing mathematical modelsResource poor countriesPoor countriesCognitive interviewsLMIC populationsDisproportionate burdenQuantitative dataCommunicable diseasesStudy sitesPrevention strategiesContact diariesGroup discussionsStudy proceduresStudy toolDisease modelsVaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis
Pischel L, Martini B, Yu N, Cacesse D, Tracy M, Kharbanda K, Ahmed N, Patel K, Grimshaw A, Malik A, Goshua G, Omer S. Vaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis. Vaccine 2024, 42: 126053. PMID: 38906763, DOI: 10.1016/j.vaccine.2024.06.021.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricConceptsPost-exposure prophylaxisMVA-BNVaccine effectivenessMeta-analysisTime of administrationNewcastle-Ottawa ScaleRisk of publication biasMeasuring vaccine efficacyImmortal time biasImmunogenicity studiesNewcastle-OttawaWeb of ScienceVaccine efficacyAnimal studiesEgger's testDisease severityFunnel plotPrimary searchDosePublication biasStudy qualityVaccineSystematic reviewVaccination timingMpox outbreakCharacterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut
Roberts S, Willebrand K, Fredrick J, Pischel L, Patel K, Murray T, Martinello R. Characterizing healthcare personnel attitudes toward receipt of a voluntary bivalent COVID-19 booster vaccine during a COVID-19 outbreak at a behavioral health hospital in Connecticut. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e87. PMID: 38774120, PMCID: PMC11106727, DOI: 10.1017/ash.2024.78.Peer-Reviewed Original ResearchCitationsAltmetricLung infections due to emerging fungal pathogens
Roman F, Pischel L, Azar M. Lung infections due to emerging fungal pathogens. Current Opinion In Pulmonary Medicine 2024, 30: 258-265. PMID: 38411158, DOI: 10.1097/mcp.0000000000001059.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricMeSH Keywords and ConceptsConceptsEndemic mycosesManagement of pulmonary infectionsFungal pathogensPathogenic fungiAntifungal prophylaxisBlastomyces speciesFungal infectionsFungal organismsAspergillus moldsEnvironmental changesImmunocompromised hostsPulmonary infectionTherapeutic challengeLung infectionMycosesClinical evidenceClinical managementIncreased incidencePulmonary diseaseEnlarged poolDisease burdenInfectionLomentosporaScedosporiumDiagnostic capabilities
2022
Serum Neutralizing Antibody Titers 12 Months After Coronavirus Disease 2019 Messenger RNA Vaccination: Correlation to Clinical Variables in an Adult, US Population
Zhao M, Slotkin R, Sheth AH, Pischel L, Kyriakides TC, Emu B, McNamara C, Shi Q, Delgobbo J, Xu J, Marhoffer E, Mercer-Falkoff A, Holleck J, Ardito D, Sutton RE, Gupta S. Serum Neutralizing Antibody Titers 12 Months After Coronavirus Disease 2019 Messenger RNA Vaccination: Correlation to Clinical Variables in an Adult, US Population. Clinical Infectious Diseases 2022, 76: e391-e399. PMID: 35639598, PMCID: PMC9278145, DOI: 10.1093/cid/ciac416.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMonth postboosterRNA vaccinationClinical variablesNeutralization responseEnd-stage renal diseaseBooster dose responsePrimary series vaccinationPrimary vaccine seriesMultiple clinical factorsSystemic steroid useDoses of vaccinePrior COVID-19Maximal inhibitory concentration valuesHalf maximal inhibitory concentration (IC50) valuesSeries vaccinationVaccine seriesVaccine regimensClinical factorsDiabetes mellitusRenal diseaseComorbid conditionsSteroid useCOVID infectionImmune responseUS population
Academic Achievements & Community Involvement
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Honors
honor Janeway Society Member
10/10/2024Yale School of Medicine Award
Clinical Care
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Overview
Lauren Pischel, MD, is an infectious disease specialist who focuses on managing and treating infectious diseases. She specializes in understanding the transmission and impact of diseases such as COVID-19 and influenza, while also working to estimate vaccine effectiveness. She uses a variety of methods to study how these diseases spread within households and communities.
As an assistant professor of medicine at Yale School of Medicine, Dr. Pischel is involved in research concerning the epidemiology of respiratory pathogens and emerging infectious diseases. She also examines how climate change and environmental factors affect infectious disease patterns.
Dr. Pischel received her medical training at Stanford School of Medicine and completed her residency in internal medicine at Yale, where she also pursued a fellowship in infectious diseases.
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News
- December 17, 2025Source: Yahoo Lifestyle
The One Thing That Reliably Kills Norovirus and How to Keep it From Spreading in Your Home
- December 25, 2024Source: SELF
Walking Pneumonia Is on the Rise. Here Are the Symptoms to Look Out For
- July 27, 2022
New Appointments & Promotions Within Department of Internal Medicine
- December 02, 2020
Infectious Disease Fellowship Supports Doctor’s Research
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Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.