Jacquelyne Gaddy, MD, MSc, MSCR
Cards
Appointments
Additional Titles
Deputy Director, Diversity Enhancement Program in Oncology
Contact Info
Appointments
Additional Titles
Deputy Director, Diversity Enhancement Program in Oncology
Contact Info
Appointments
Additional Titles
Deputy Director, Diversity Enhancement Program in Oncology
Contact Info
About
Titles
Assistant Professor
Deputy Director, Diversity Enhancement Program in Oncology
Biography
Jacquelyne Gaddy, MD, MSc, MSCR is an Assistant Professor in the Department of Medicine (Medical Oncology) and cares for patients as part of the Center for Gastrointestinal Cancers at Smilow Cancer Hospital and Yale Cancer Center. She is also Deputy Director of the Diversity Enhancement Program in Oncology and a member of The Center for Community Engagement and Health Equity (CEHE) within Smilow Cancer Hospital and Yale Cancer Center.
Prior to medical school she pursued a Master of Cancer Sciences at Roswell Park Comprehensive Cancer Center. Dr. Gaddy received her medical degree from Loyola University Chicago Stritch School of Medicine. She completed her residency at the University at Buffalo and while a fellow in medical oncology at the University of North Carolina at Chapel Hill, undertook a post-doctoral fellowship in the Department of Health Behavior and obtained a Master of Science in Clinical Research (MSCR).
Dr. Gaddy has dedicated her entire postgraduate career to focusing on improving diversity, equity, and inclusion. She is committed to improving cancer care delivery for Black patients while also addressing the needs of Black, Indigenous, People of color (BIPOC) cancer care providers through an educational and investigational approach. Her primary research focus is evaluating how the social determinants of health impact cancer care delivery. She is a 2012 recipient of the Medical Student Rotation for Underrepresented Populations and a 2019 recipient of the Resident Travel Award for Underrepresented Populations from Conquer Cancer, the ASCO Foundation. She was selected to participate in Dr. Kemi Doll’s “Get That Grant” coaching program, is Co-Director of the Oncology Summer Internship (sponsored by ASCO), and holds a 2023 ACS IRG Pilot Award for Underrepresented Minorities.
Appointments
Medical Oncology
Assistant ProfessorPrimary
Other Departments & Organizations
- Cancer Prevention and Control
- Center for Community Engagement and Health Equity (CEHE)
- Center for Gastrointestinal Cancers
- Hepatic Arterial Infusion (HAI) Program
- Hyperthermic intraperitoneal chemotherapy (HIPEC) Program
- Internal Medicine
- Medical Oncology
- Oligometastatic Cancer Program
- Yale Cancer Center
- Yale Medicine
Education & Training
- MSCR
- University of North Carolina at Chapel Hill, Public Health
- MD
- Loyola University Chicago Stritch School of Medicine (2016)
- MSc
- University at Buffalo, Cancer Sciences (2010)
Research
Overview
Medical Subject Headings (MeSH)
Research at a Glance
Publications Timeline
Research Interests
Healthcare Disparities
Publications
2024
A phase II trial of UGT1A1 genotype-guided FOLFIRI plus bevacizumab as first-line therapy for advanced, unresectable colorectal cancer
Sanoff H, Deal A, Patel J, Sorah J, Gaddy J, O’Neil B, Turk A, Irvin W, Boles J, Lee M, McRee A, Wardell A, Weck K, Basch E, Wood W, Innocenti F. A phase II trial of UGT1A1 genotype-guided FOLFIRI plus bevacizumab as first-line therapy for advanced, unresectable colorectal cancer. The Oncologist 2024, oyae122. PMID: 38837045, DOI: 10.1093/oncolo/oyae122.Peer-Reviewed Original ResearchAltmetricConceptsProgression-free survivalMetastatic colorectal cancerOverall survivalIrinotecan doseColorectal cancerMedian progression-free survivalMetastatic colorectal cancer patientsEstimates of overall survivalFirst-line settingUnresectable colorectal cancerRates of neutropeniaFirst-line therapyPhase II trialPatient-reported adverse eventsRate of diarrheaG3/4 toxicitiesUGT1A1 genotypeIrinotecan metabolismFirst-linePrimary endpointSecondary endpointsAdverse eventsFOLFIRIHistorical controlsNon-genotypeGenetic ancestry-associated differences in genomic profiling and treatment patterns in pancreatic ductal adenocarcinoma (PDAC).
Gaddy J, Li G, Keller-Evans R, Bray D, MILLS J, Oberstein P, Kunz P, Sivakumar S. Genetic ancestry-associated differences in genomic profiling and treatment patterns in pancreatic ductal adenocarcinoma (PDAC). Journal Of Clinical Oncology 2024, 42: 4138-4138. DOI: 10.1200/jco.2024.42.16_suppl.4138.Peer-Reviewed Original ResearchConceptsPancreatic ductal adenocarcinomaClinico-genomic databaseGenetic ancestryAFRS patientsSocioeconomic statusPattern of gene alterationsPotential impact of genomicsSNP-based approachTreatment patternsGenomic profilingPopulation-level risk factorsImpact of genomicsCancer treatment courseClinical care patternsLow socioeconomic statusComprehensive genomic profilingOverall US populationNon-genomic factorsYounger median ageRate of surgeryImpact patient outcomesGenomic differencesAncestry distributionGenomic landscapeAncestry groups
2023
Abstract C129: Impact of COVID-19 on colorectal cancer screening disparities: Results from a large commercially insured population in the United States
Siddique A, Wang R, Gaddy J, Gross C, Ma X. Abstract C129: Impact of COVID-19 on colorectal cancer screening disparities: Results from a large commercially insured population in the United States. Cancer Epidemiology Biomarkers & Prevention 2023, 32: c129-c129. DOI: 10.1158/1538-7755.disp23-c129.Peer-Reviewed Original ResearchConceptsBlue Cross Blue ShieldColorectal cancer screeningColorectal cancer screening disparitiesLow socioeconomic statusCancer screening disparitiesScreening ratesHigher socioeconomic statusSocioeconomic statusScreening disparitiesCommercially insured populationColorectal cancerColorectal cancer screening ratesImpact of COVID-19Burden of colorectal cancerColorectal cancer incidenceCancer health disparitiesCRC-related mortalityNeighborhood socioeconomic statusSocioeconomic status quintileSocial deprivation indexSocioeconomic status areasNon-Hispanic blacksNon-urgent careSocially deprived areasEthnic minoritized populationsRace, geography, and risk of breast cancer treatment delays: A population‐based study 2004–2015
Reeder‐Hayes K, Jackson B, Baggett C, Kuo T, Gaddy J, LeBlanc M, Bell E, Green L, Wheeler S. Race, geography, and risk of breast cancer treatment delays: A population‐based study 2004–2015. Cancer 2023, 129: 925-933. PMID: 36683417, DOI: 10.1002/cncr.34573.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBreast cancer treatment delaysTreatment delayMagnitude of racial disparitiesNon-Black patientsStage I-III breast cancerI-III breast cancerPoor-quality carePopulation health resourcesRisk of treatment delayBlack patientsBreast cancer survivalCancer treatment delayPopulation-based studyDiagnosis to first treatmentAssociated with riskBreast cancerCancer RegistryObservational cohort of patientsTreatment delay >Health resourcesPopulation-basedPoisson regressionCancer survivalSociodemographic dataRacial disparitiesObesity, Cancer, and Health Equity
Nyrop K, Gaddy J, Charlot M. Obesity, Cancer, and Health Equity. American Journal Of Preventive Medicine 2023, 64: 595-598. PMID: 36610923, DOI: 10.1016/j.amepre.2022.10.024.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsSeeking Racial Equity in Hematology and Oncology: a Fellow-Led Educational Series to Promote Reflection and Action
Stein J, Gaddy J, Sorah J, Wooten M, Gibson K, Collichio F. Seeking Racial Equity in Hematology and Oncology: a Fellow-Led Educational Series to Promote Reflection and Action. Journal Of Cancer Education 2023, 38: 1241-1244. PMID: 36598746, PMCID: PMC10463164, DOI: 10.1007/s13187-022-02255-8.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsGraduate medical education programsHealth system levelMedical education programsEffects of implicit biasImproved comfort levelRacial inequalitySystemic racismAwareness of racial inequalityMedical residentsImprove awarenessRacial equityImprove knowledgeGroup discussionsEducation programsUniversity of North CarolinaLikert scaleEducation seriesImplicit biasComfort levelLay mediaEducational gapLived experiencePerceptions of racial inequalityParticipantsEducation curriculum
2022
Addressing Racial, Ethnic, and Age Disparities in Cancer Clinical Trial Enrollment
Gaddy JJ, Gross CP. Addressing Racial, Ethnic, and Age Disparities in Cancer Clinical Trial Enrollment. JAMA Oncology 2022, 8: 1792-1793. PMID: 36301581, DOI: 10.1001/jamaoncol.2022.5006.Peer-Reviewed Original ResearchCitationsAltmetricEvaluation of facilitators and barriers of timely breast cancer care in North Carolina (NC): A qualitative study.
Gaddy J, Teal R, Bell E, Wheeler S, Reeder-Hayes K. Evaluation of facilitators and barriers of timely breast cancer care in North Carolina (NC): A qualitative study. Journal Of Clinical Oncology 2022, 40: 134-134. DOI: 10.1200/jco.2022.40.28_suppl.134.Peer-Reviewed Original ResearchConceptsCancer care deliverySocial determinants of healthArea Health Education CenterDeterminants of healthBreast cancer careSocial determinantsCare deliveryCancer careBlack patientsHealthcare systemQuality of cancer careQualitative studyIdentification of emergent themesInitiation of breast cancer treatmentOverall quality of cancer careAdverse social determinantsPatients' social determinantsProvision of social support servicesBreast cancer cliniciansHealth Education CenterSupportive healthcare providersSocial support servicesNorth CarolinaTreatment delayNon-black womenSeeking racial equity in hematology and oncology: A fellow-led educational series to promote reflection and action.
Stein J, Gaddy J, Sorah J, Wooten M, Gibson K, Collichio F. Seeking racial equity in hematology and oncology: A fellow-led educational series to promote reflection and action. Journal Of Clinical Oncology 2022, 40: 11004-11004. DOI: 10.1200/jco.2022.40.16_suppl.11004.Peer-Reviewed Original ResearchAltmetricConceptsUniversity of North CarolinaImplicit biasSystemic racismAwareness of implicit biasAcademic medical centerPatients of colorRacial inequalityHealth disparitiesImprove careImprove racial equityEducation curriculumAwareness of racial inequalityOncology fellowsJournal clubRacial equityImprove knowledgeGroup discussionsLikert scaleMedical CenterEducation seriesComfort levelLay mediaLived experiencePerceptions of racial inequalityParticipantsIntegrated approach to collecting patient reported toxicities in a colorectal cancer trial.
Gaddy J, Sanoff H, Deal A, Basch E, Wood W. Integrated approach to collecting patient reported toxicities in a colorectal cancer trial. Journal Of Clinical Oncology 2022, 40: 51-51. DOI: 10.1200/jco.2022.40.4_suppl.051.Peer-Reviewed Original ResearchConceptsDose decreaseSevere symptomsToxicity ratesSevere toxicityClinical trialsGenotype-guided dosing strategyAppropriate dose modificationPRO-CTCAEStandard drug dosesAdverse event assessmentMulti-center clinical trialClinically relevant issuesColorectal cancer trialsHematologic toxicityMCRC patientsDose modificationAbdominal painAdvanced CRCToxicity gradeCycling patientsClinical characteristicsDosing strategiesAdverse eventsDrug doseClinician grading
Clinical Care
Overview
Clinical Specialties
Fact Sheets
Gastrointestinal Cancers
Learn More on Yale MedicineSmall Intestine Adenocarcinoma
Learn More on Yale MedicineColorectal Cancer
Learn More on Yale MedicineAnesthesia for Colonoscopy
Learn More on Yale Medicine
Board Certifications
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
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News
- October 03, 2024
Study Reveals Disparities in Colorectal Cancer Screening
- August 19, 2024
Yale Cancer Answers with Dr. Jacquelyne Gaddy
- June 07, 2024
Yale Cancer Center Researchers and Trainees Present at ASCO
- September 28, 2023
Meet Yale Internal Medicine: Jacquelyne Gaddy, MD, MSc, MSCR, Assistant Professor of Medicine (Medical Oncology)
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Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
Events
Everyone Roy S. Herbst, MD, PhD - Maryam Lustberg, MD, MPH - Sarah Goldberg, MD, MPH - Jacquelyne Gaddy, MD, MSc, MSCR - Jessica Lewis, PhD, LMFT - Ian Krop, MD, PhD - Lajos Pusztai, MD, DPhil