Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsConnie Hsaio, MD
she/her/hers
Assistant Professor Adjunct of PsychiatryAbout
Research
Publications
2026
Latent classes of sleep deficiency and correlates among patients receiving methadone treatment: A longitudinal study
Hsaio C, Jeon S, DiMeola K, Walker K, Akhiwu O, Stein M, Madden L, Redeker N, Scheinost D, Fiellin D, Yaggi H, Barry D. Latent classes of sleep deficiency and correlates among patients receiving methadone treatment: A longitudinal study. Addiction 2026 PMID: 41852290, DOI: 10.1111/add.70384.Peer-Reviewed Original ResearchPositive urine toxicologyUrine toxicologyMethadone treatmentTreatment continuationPain interferencePain interference with sleepClass IIIClass ILate sleepObstructive sleep apneaOne-year treatment outcomesUrine toxicology resultsSleep deficiencyClass II-IVRestless legs syndromeEpworth Sleepiness ScaleRestless Legs Syndrome QuestionnairePatient-completed questionnairesSTOP questionnaireSleep apneaInterfere with sleepOpioid treatment programsClinical characteristicsPsychological symptomsMedical charts
2025
Perceived Importance of Counseling Among Patients Receiving Methadone Treatment
Barry D, Beitel M, Gazzola M, Agerwala S, Saeed G, Eggert K, Roehrich T, Hsaio C, Covelli M, Carmichael I, Madden L, Hammouri M. Perceived Importance of Counseling Among Patients Receiving Methadone Treatment. Journal Of Psychoactive Drugs 2025, ahead-of-print: 1-8. PMID: 40143754, DOI: 10.1080/02791072.2025.2484374.Peer-Reviewed Original ResearchM118 Counselor Terminological Preferences for Common Treatment Experiences Among Patients Receiving Methadone Treatment
Eggert K, Walker K, Beitel M, Cammack K, Rossi R, Gazzola M, Hsaio C, Roehrich T, Madden L, Barry D. M118 Counselor Terminological Preferences for Common Treatment Experiences Among Patients Receiving Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 111712. DOI: 10.1016/j.drugalcdep.2024.111712.Peer-Reviewed Original ResearchW64 The use of the Pittsburgh Sleep Quality Index to Screen for Different Types of Sleep Disturbance in Opioid Treatment Programs
Hsaio C, DiMeola K, Walker K, Stein M, Yaggi K, Barry D. W64 The use of the Pittsburgh Sleep Quality Index to Screen for Different Types of Sleep Disturbance in Opioid Treatment Programs. Drug And Alcohol Dependence 2025, 267: 112006. DOI: 10.1016/j.drugalcdep.2024.112006.Peer-Reviewed Original Research
2024
Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review
Hsaio C, DiMeola K, Jegede O, Funaro M, Langstengel J, Yaggi H, Barry D. Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review. Current Addiction Reports 2024, 11: 965-981. PMID: 39886383, PMCID: PMC11781152, DOI: 10.1007/s40429-024-00606-7.Peer-Reviewed Original ResearchOpioid use disorderOUD severityUse disorderTreatment characteristicsOpioid use disorder treatment settingsTreatment of sleepDosing scheduleDisorder severityOpioidPainWeb of ScienceAssessed patientsCochrane LibraryMeasures of sleepMOUD treatmentCurrent evidenceMOUDSleepSleep disturbanceProvider preferencesPatientsStudy examined sleepDisordersTreatment settingsMedicationThe Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review
Jegede O, De Aquino J, Hsaio C, Caldwell E, Funaro M, Petrakis I, Muvvala S. The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review. Journal Of Addiction Medicine 2024, 18: 499-510. PMID: 39356620, PMCID: PMC11449257, DOI: 10.1097/adm.0000000000001356.Peer-Reviewed Original ResearchNonmedical opioid useOpioid use disorderOpioid useWithdrawal symptomsTreatment outcomesSymptoms prior to treatmentUse disorderRisk of precipitated withdrawalLow-dose buprenorphineSynthetic opioidsPotency synthetic opioidsConclusions Current evidencePrecipitated withdrawalRisk of overdoseDosing strategiesPharmacological interactionsClinical significanceDecreased riskWeb of ScienceOpioidInclusion criteriaCurrent evidenceClinical implicationsMOUDPainA Quantitative Examination of Illness Models Among People With Opioid Use Disorder Receiving Methadone Treatment
Gazzola M, Carmichael I, Thompson E, Beitel M, Madden L, Saeed G, Hoffman K, Hammouri M, Hsaio C, Barry D. A Quantitative Examination of Illness Models Among People With Opioid Use Disorder Receiving Methadone Treatment. Journal Of Addiction Medicine 2024, 18: 262-268. PMID: 38446859, DOI: 10.1097/adm.0000000000001282.Peer-Reviewed Original ResearchBrain disease modelMethadone treatmentTreatment beliefsIllness modelAssociated with beliefsOpioid use disorderUse disorderOutpatient opioid treatment programAddiction modelTreatment programsOpioid treatment programsAddictionMethadoneMultivariate analysisScale agreementIllnessDisordersCounselingBrainBeliefsDisease modelsOpioidPatientsStatistical significanceMultivariate regression
2017
Transgenic Expression of the Vitamin D Receptor Restricted to the Ileum, Cecum, and Colon of Vitamin D Receptor Knockout Mice Rescues Vitamin D Receptor−Dependent Rickets
Dhawan P, Veldurthy V, Yehia G, Hsaio C, Porta A, Kim K, Patel N, Lieben L, Verlinden L, Carmeliet G, Christakos S. Transgenic Expression of the Vitamin D Receptor Restricted to the Ileum, Cecum, and Colon of Vitamin D Receptor Knockout Mice Rescues Vitamin D Receptor−Dependent Rickets. Endocrinology 2017, 158: 3792-3804. PMID: 28938396, PMCID: PMC5695835, DOI: 10.1210/en.2017-00258.Peer-Reviewed Original ResearchConceptsVitamin D receptorVDR KO miceKO miceVDR deficiencyDistal intestineHuman VDRD receptorElevated parathyroid hormone levelsExpression of vitamin D receptorCalcium homeostasisLow VDR expressionParathyroid hormone levelsIntestinal calcium absorptionMicrocomputed tomography analysisVDR expressionKO/TG miceGrowth plate abnormalitiesTg miceCalcium absorptionHormone levelsHuman vitamin D receptorTg linesTransgene expressionCortical parametersMice
2016
The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle
Mady L, Ajibade D, Hsaio C, Teichert A, Fong C, Wang Y, Christakos S, Bikle D. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle. Journal Of Investigative Dermatology 2016, 136: 1337-1345. PMID: 26994969, PMCID: PMC9020884, DOI: 10.1016/j.jid.2016.02.813.Peer-Reviewed Original ResearchConceptsVitamin D deficiencyKnockout pupsD deficiencyHair follicle cyclingCalbindin-D9KFollicle cyclingLoss of hair shaftsLow calcium dietKeratin 1 expressionExpression of involucrinDystrophic hair folliclesAlopecia totalisTransient alopeciaVitamin DKnockout femalesNormal dietDesmoglein 3Spontaneous recoveryHyperplastic epidermisNoncicatricial alopeciaLow calciumPupsAlopeciaHair folliclesHistological studies