2024
Mental health and lower adolescent HPV vaccine coverage
Ellingson M, Brewer N. Mental health and lower adolescent HPV vaccine coverage. The Lancet Public Health 2024, 9: e642-e643. PMID: 39214634, DOI: 10.1016/s2468-2667(24)00190-7.Peer-Reviewed Original Research
2023
Human papillomavirus vaccine effectiveness by age at vaccination: A systematic review
Ellingson M, Sheikha H, Nyhan K, Oliveira C, Niccolai L. Human papillomavirus vaccine effectiveness by age at vaccination: A systematic review. Human Vaccines & Immunotherapeutics 2023, 19: 2239085. PMID: 37529935, PMCID: PMC10399474, DOI: 10.1080/21645515.2023.2239085.Peer-Reviewed Original ResearchConceptsVaccine effectivenessSystematic reviewHuman Papillomavirus Vaccine EffectivenessVaccine-type HPV infectionYounger ageHigh vaccine effectivenessHuman papillomavirus vaccineVaccine effectiveness studiesYounger age groupsAdolescents ages 15Adolescents ages 9HPV infectionHPV vaccineVaccine initiationPapillomavirus vaccineTime vaccinationAnogenital wartsCervical abnormalitiesCervical cancerDisease outcomeAge groupsOlder ageEffectiveness studiesAge 15Age
2022
MomsTalkShots, tailored educational app, improves vaccine attitudes: a randomized controlled trial
Dudley M, Omer S, O’Leary S, Limaye R, Ellingson M, Spina C, Brewer S, Bednarczyk R, Chamberlain A, Malik F, Frew P, Church-Balin C, Riley L, Ault K, Orenstein W, Halsey N, Salmon D. MomsTalkShots, tailored educational app, improves vaccine attitudes: a randomized controlled trial. BMC Public Health 2022, 22: 2134. PMID: 36411403, PMCID: PMC9676851, DOI: 10.1186/s12889-022-14498-7.Peer-Reviewed Original ResearchConceptsInfluenza vaccine efficacyPregnant womenVaccine knowledgeProvider interventionsVaccine efficacyInfluenza diseaseVaccine intentionsVaccine attitudesPatient-level componentVaccine safety concernsPractice-level interventionPrenatal care practicesMulti-level interventionsHalf of participantsInfant vaccinesVaccine uptakeVaccine informationVaccine hesitancyStudy staffInfant's birthCare practicesBaseline surveyWomenDiseaseInterventionMulti-tiered intervention to increase maternal immunization coverage: A randomized, controlled trial
Omer SB, O'Leary ST, Bednarczyk RA, Ellingson MK, Spina CI, Dudley MZ, Chamberlain AT, Limaye RJ, Brewer SE, Frew PM, Malik FA, Orenstein W, Halsey N, Ault K, Salmon DA. Multi-tiered intervention to increase maternal immunization coverage: A randomized, controlled trial. Vaccine 2022, 40: 4955-4963. PMID: 35817646, DOI: 10.1016/j.vaccine.2022.06.055.Peer-Reviewed Original ResearchConceptsPatient-level interventionsVaccine uptakeStudy armsInfluenza vaccineLow vaccine confidenceInfluenza vaccine uptakeAcellular pertussis vaccinePatient-level barriersProvider-level interventionsEvidence-based interventionsAcellular pertussisPertussis vaccinePrimary outcomeCare clinicsPregnant womenMulti-component intervention packageControl armImmunization uptakeObstetric practiceImmunization coverageSample sizeVaccine confidenceFinal sample sizeControl groupTargeted interventions
2021
Vaccine package inserts and prescribing habits of obstetricians-gynecologists for maternal vaccination
Saini J, Ellingson MK, Beigi RH, MacDonald NE, Top KA, Carroll S, Omer SB. Vaccine package inserts and prescribing habits of obstetricians-gynecologists for maternal vaccination. Human Vaccines & Immunotherapeutics 2021, 17: 3761-3770. PMID: 34236947, PMCID: PMC8437486, DOI: 10.1080/21645515.2021.1942714.Peer-Reviewed Original ResearchConceptsVaccine package insertsLactation Labeling RulePackage insertsMaternal vaccinationPregnant womenProvider recommendationDrug Administration (FDA) package insertAcellular pertussis vaccineEffectiveness of vaccinesCurrent clinical practiceCross-sectional surveyInfluenza vaccinePertussis vaccineVaccine uptakeGynecologists FellowsAmerican CollegeClinical practicePregnancyMost providersVaccineVaccinationWeighted sampleTwo-thirdsWomenLabeling rulesStrategies to increase uptake of maternal pertussis vaccination
Patel KM, Guillamet L, Pischel L, Ellingson MK, Bardají A, Omer SB. Strategies to increase uptake of maternal pertussis vaccination. Expert Review Of Vaccines 2021, 20: 779-796. PMID: 34129416, PMCID: PMC9288655, DOI: 10.1080/14760584.2021.1940146.Peer-Reviewed Original ResearchConceptsMaternal pertussis vaccinationPertussis vaccinationInteractive patient educationContagious respiratory diseaseLack of studiesMaternal uptakePostpartum vaccinationPrenatal vaccinationSite vaccinationVaccine seriesMiddle-income countriesPertussis vaccineVaccine uptakePregnant womenProvider educationDisproportionate morbidityPatient educationSuboptimal uptakeVaccine communicationRespiratory diseaseVaccinationHome birthSystematic reviewDifferent interventionsInfantsPatterns of recommended vaccine receipt among women ages 24–45 years: a cross-sectional analysis
Ellingson MK, Oliveira CR, Sheth SS, Sullivan EL, Torres A, Shapiro ED, Niccolai LM. Patterns of recommended vaccine receipt among women ages 24–45 years: a cross-sectional analysis. BMC Public Health 2021, 21: 1283. PMID: 34193100, PMCID: PMC8247221, DOI: 10.1186/s12889-021-11340-4.Peer-Reviewed Original ResearchConceptsMid-adult womenVaccine receiptCross-sectional analysisHPV vaccineOngoing case-control studyReceipt of influenzaHealth care visitsCase-control studyWomen ages 24Quarter of adultsLogistic regression analysisCare visitsIndividual vaccinesHealthcare utilizationMultiple vaccinesVaccineAge 24White womenWomenDemographic characteristicsRegression analysisLower ratesInfluenzaReceiptPast yearRacial/Ethnic Disparities in Maternal Vaccine Knowledge, Attitudes, and Intentions
Dudley MZ, Limaye RJ, Salmon DA, Omer SB, O’Leary S, Ellingson MK, Spina CI, Brewer SE, Bednarczyk RA, Malik F, Frew PM, Chamberlain AT. Racial/Ethnic Disparities in Maternal Vaccine Knowledge, Attitudes, and Intentions. Public Health Reports 2021, 136: 699-709. PMID: 33508208, PMCID: PMC8579395, DOI: 10.1177/0033354920974660.Peer-Reviewed Original ResearchConceptsRace/ethnicityInfant vaccinesVaccine knowledgeVaccine acceptanceOdds ratioWhite womenMaternal influenza vaccineAcellular pertussis vaccinePregnant women's knowledgeRacial/Ethnic DisparitiesVaccine-preventable diseasesMultiple logistic regressionPrenatal care practicesHealth care providersPublic health authoritiesDifferent races/ethnicitiesMaternal tetanusMaternal vaccinesInfluenza vaccinePertussis vaccinePregnant womenVaccine safetyVaccine informationVaccine decisionsCare providers
2020
Adapting Center for Disease Control and Prevention's immunization quality improvement program to improve maternal vaccination uptake in obstetrics
Spina CI, Brewer SE, Ellingson MK, Chamberlain AT, Limaye RJ, Orenstein WA, Salmon DA, Omer SB, O'Leary ST. Adapting Center for Disease Control and Prevention's immunization quality improvement program to improve maternal vaccination uptake in obstetrics. Vaccine 2020, 38: 7963-7969. PMID: 33121843, PMCID: PMC9375227, DOI: 10.1016/j.vaccine.2020.10.051.Peer-Reviewed Original ResearchConceptsMaternal vaccination ratesVaccination ratesMaternal vaccinationObstetric practiceObstetric settingDisease controlMaternal vaccination uptakeRandom chart reviewInfluenza vaccination ratesPertussis vaccination ratesState health departmentsQuality Improvement ProgramMulti-level interventionsHealth care specialtiesTdap vaccineChart reviewVaccination uptakeVaccine uptakeImmunization championClinical priorityChild healthQI strategiesEvidence-based modelHealth departmentsHealth record systemsSex differences in immune responses that underlie COVID-19 disease outcomes
Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Casanovas-Massana A, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Shaw A, Fournier J, Odio C, Farhadian S, Dela Cruz C, Grubaugh N, Schulz W, Ring A, Ko A, Omer S, Iwasaki A. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature 2020, 588: 315-320. PMID: 32846427, PMCID: PMC7725931, DOI: 10.1038/s41586-020-2700-3.Peer-Reviewed Original ResearchConceptsInnate immune cytokinesFemale patientsMale patientsImmune cytokinesDisease outcomeImmune responseCOVID-19COVID-19 disease outcomesPoor T cell responsesSARS-CoV-2 infectionSevere acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusSex-based approachModerate COVID-19Sex differencesRobust T cell activationT cell responsesWorse disease progressionWorse disease outcomesHigher plasma levelsNon-classical monocytesCoronavirus disease 2019T cell activationImmunomodulatory medicationsPlasma cytokinesLongitudinal analyses reveal immunological misfiring in severe COVID-19
Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A, Herbst R, Shaw A, Medzhitov R, Schulz W, Grubaugh N, Dela Cruz C, Farhadian S, Ko A, Omer S, Iwasaki A. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature 2020, 584: 463-469. PMID: 32717743, PMCID: PMC7477538, DOI: 10.1038/s41586-020-2588-y.Peer-Reviewed Original ResearchConceptsSevere COVID-19Moderate COVID-19Immune signaturesDisease outcomeCOVID-19Disease trajectoriesInterleukin-5Early immune signaturesInnate cell lineagesType 2 effectorsT cell numbersPoor clinical outcomeWorse disease outcomesImmune response profileCoronavirus disease 2019Distinct disease trajectoriesCytokine levelsImmunological correlatesImmune profileClinical outcomesEarly elevationImmune profilingIL-13Immunoglobulin EDisease 2019Latent Class Analysis of Maternal Vaccine Attitudes and Beliefs
Dudley MZ, Limaye RJ, Omer S, O’Leary S, Ellingson M, Spina C, Chamberlain A, Brewer SE, Bednarczyk RA, Malik F, Frew PM, Salmon D. Latent Class Analysis of Maternal Vaccine Attitudes and Beliefs. Health Education & Behavior 2020, 47: 765-781. PMID: 32639167, DOI: 10.1177/1090198120939491.Peer-Reviewed Original ResearchConceptsPregnant womenVaccine attitudesLatent class analysisEducational interventionPrenatal care practicesVaccine acceptorsClass analysisFirst pregnancyVaccine coverageVaccine safetyVaccine informationCare practicesDisease severityWomenSubstantial proportionMost parentsDisease susceptibilityVaccine skepticsVaccine supportersAudience segmentationInterventionGroupSurvey itemsPatient Decision Making Related to Maternal and Childhood Vaccines: Exploring the Role of Trust in Providers Through a Relational Theory of Power Approach
Limaye RJ, Malik F, Frew PM, Randall LA, Ellingson MK, O’Leary S, Bednarczyk RA, Oloko O, Salmon DA, Omer SB. Patient Decision Making Related to Maternal and Childhood Vaccines: Exploring the Role of Trust in Providers Through a Relational Theory of Power Approach. Health Education & Behavior 2020, 47: 449-456. PMID: 32306760, DOI: 10.1177/1090198120915432.Peer-Reviewed Original ResearchConceptsObstetric providersPregnant womenContext of vaccinesChildhood vaccinesVaccination ratesVaccine acceptanceVaccine decisionsPatient decisionOb-gynsInfectious diseasesPatientsWomen's trustWomenVaccineMedical experiencePurposive sampleRelational theoryProvidersMedical credentialsPower dynamicsDepth interviewsRole of trustDistributive powerVaccinationImmunizationFactors associated with referring close contacts to an app with individually-tailored vaccine information
Dudley MZ, Limaye RJ, Omer SB, O'Leary ST, Ellingson MK, Spina CI, Brewer SE, Chamberlain AT, Bednarczyk RA, Malik F, Frew PM, Salmon DA. Factors associated with referring close contacts to an app with individually-tailored vaccine information. Vaccine 2020, 38: 2827-2832. PMID: 32098739, PMCID: PMC10690757, DOI: 10.1016/j.vaccine.2020.02.019.Peer-Reviewed Original ResearchConceptsMaternal influenza vaccineVaccine informationCocooning strategyInfluenza vaccinePregnant womenVaccine intentionsSeverity of influenzaPrenatal care practicesTdap vaccineInfant vaccinesPertussis infectionVaccine coverageVaccine educationMost referralsVaccine confidenceCare practicesVaccineDisease controlVulnerable timeWomenNational InstituteInfantsInfluenzaFamily membersClose contactCharacterizing the vaccine knowledge, attitudes, beliefs, and intentions of pregnant women in Georgia and Colorado
Dudley MZ, Limaye RJ, Omer SB, O’Leary S, Ellingson MK, Spina CI, Brewer SE, Chamberlain AT, Bednarczyk RA, Malik F, Frew PM, Salmon DA. Characterizing the vaccine knowledge, attitudes, beliefs, and intentions of pregnant women in Georgia and Colorado. Human Vaccines & Immunotherapeutics 2020, 16: 1109-1117. PMID: 32078395, PMCID: PMC7227625, DOI: 10.1080/21645515.2020.1717130.Peer-Reviewed Original ResearchConceptsPregnant womenTdap vaccineInfant vaccinesVaccine safetyVaccine-preventable diseasesPrenatal care practicesFirst-time pregnant womenMaternal vaccinesVaccine knowledgeVaccine coverageVaccine educationVaccine informationVaccine confidenceCare practicesVaccineWomenFirst childPrior childrenInfluenzaChildrenSafetyPregnancyBabiesDisease
2019
MomsTalkShots: An individually tailored educational application for maternal and infant vaccines
Salmon DA, Limaye RJ, Dudley MZ, Oloko OK, Church-Balin C, Ellingson MK, Spina CI, Brewer SE, Orenstein WA, Halsey NA, Chamberlain AT, Bednarczyk RA, Malik FA, Frew PM, O'Leary ST, Omer SB. MomsTalkShots: An individually tailored educational application for maternal and infant vaccines. Vaccine 2019, 37: 6478-6485. PMID: 31506192, PMCID: PMC7144831, DOI: 10.1016/j.vaccine.2019.08.080.Peer-Reviewed Original ResearchConceptsEducational applicationsSelf-reported factorsPregnant womenSelf-reported information needsInfant vaccinesVaccine informationSource credibilityMajority of womenIntentionAdult vaccinesImmunization scheduleVaccine uptakeVaccine concernsVaccine intentionsVaccine attitudesClinical settingVaccineInitial assessmentAdolescentsWomenBeliefsParentsAttitudesDemographicsDevelopment and acceptability of a video-based vaccine promotion tutorial for obstetric care providers
Chamberlain AT, Limaye RJ, O'Leary ST, Frew PM, Brewer SE, Spina CI, Ellingson MK, Dudley MZ, Orenstein WA, Donnelly MA, Riley LE, Ault KA, Salmon DA, Omer SB. Development and acceptability of a video-based vaccine promotion tutorial for obstetric care providers. Vaccine 2019, 37: 2532-2536. PMID: 30962093, PMCID: PMC6472923, DOI: 10.1016/j.vaccine.2019.03.005.Peer-Reviewed Original ResearchConceptsObstetric care providersCare providersMaternal vaccinesHesitant patientsVaccine-hesitant patientsCare providers' abilityPregnant patientsProvider recommendationVaccine acceptanceVaccine promotionPatientsVaccine conversationsProviders' abilityStrongest predictorVaccinePractice cultureMedical education creditsProvidersAcceptabilityPregnancyVaccinationEducation creditEnhancing uptake of influenza maternal vaccine
Ellingson MK, Dudley MZ, Limaye RJ, Salmon DA, O’Leary S, Omer SB. Enhancing uptake of influenza maternal vaccine. Expert Review Of Vaccines 2019, 18: 191-204. PMID: 30587042, PMCID: PMC6378696, DOI: 10.1080/14760584.2019.1562907.Peer-Reviewed Original ResearchConceptsInfluenza vaccine uptakeVaccine uptakePregnant womenMaternal influenza vaccine uptakeVaccine coverage ratesEffectiveness of interventionsMaternal vaccinesProvider promptsVaccine receiptInfluenza vaccinationImmunization PracticesImmunization scheduleProvider recommendationMore vaccinesEffective interventionsInterventionWomenPregnancyVaccineAdvisory CommitteeImportant predictorCoverage rateUptakeSubstantial gapsPatientsHuman Papillomavirus Vaccination Before 13 and 15 Years of Age: Analysis of National Immunization Survey Teen Data
Bednarczyk RA, Ellingson MK, Omer SB. Human Papillomavirus Vaccination Before 13 and 15 Years of Age: Analysis of National Immunization Survey Teen Data. The Journal Of Infectious Diseases 2019, 220: 730-734. PMID: 30657920, PMCID: PMC6667791, DOI: 10.1093/infdis/jiy682.Peer-Reviewed Original ResearchConceptsHuman papillomavirus vaccinationHPV vaccinationPapillomavirus vaccinationNational Immunization Survey-Teen dataProvider-verified vaccination dataNational Immunization Survey-TeenYears of ageProportion of adolescentsYounger vaccineesHPV vaccineImmunization PracticesVaccination dataVaccinationHigh immunogenicityUS adolescentsAdvisory CommitteeActivity initiationAdolescentsVaccineesBetter protectionHPVVaccineCancerImmunogenicityDoses
2018
Beyond the verbal: Pregnant women's preferences for receiving influenza and Tdap vaccine information from their obstetric care providers
Ellingson M, Chamberlain AT. Beyond the verbal: Pregnant women's preferences for receiving influenza and Tdap vaccine information from their obstetric care providers. Human Vaccines & Immunotherapeutics 2018, 14: 767-771. PMID: 29313417, PMCID: PMC5861808, DOI: 10.1080/21645515.2018.1425114.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBlack or African AmericanCommunicationDiphtheria-Tetanus-acellular Pertussis VaccinesFemaleGeorgiaHealth Knowledge, Attitudes, PracticeHumansImmunizationInfluenza VaccinesInfluenza, HumanInternetPatient Acceptance of Health CarePregnancyPregnancy Complications, InfectiousPregnant WomenVaccinationYoung AdultConceptsVaccine-related informationVaccine informationPrenatal providersPregnant womenObstetric care providersPractice websitesHealth informationPregnant women's preferencesChi-square testPrenatal health informationAfrican American womenRace/ethnicityVaccine receiptMaternal immunizationObstetric patientsProvider recommendationPrenatal clinicsCare providersEducational brochureCDC websiteParticipant characteristicsWhite womenWomen's informationWomenClinical conversations