Sleep Disorders

• Impact of continuous positive airway pressure therapy on restless legs syndrome in patients with coexistent obstructive sleep apnea: A qualitative systematic review.Srivali N, Thongprayoon C, Cheungpasitporn W, Zinchuk A, Koo BB. J Clin Neurosci. 2025 Mar; 2025 Jan 28. PMID: 39879879.
• Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline.Winkelman JW, Berkowski JA, DelRosso LM, Koo BB, Scharf MT, Sharon D, Zak RS, Kazmi U, Falck-Ytter Y, Shelgikar AV, Trotti LM, Walters AS. J Clin Sleep Med. 2025 Jan 1. PMID: 39324694.
• Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Winkelman JW, Berkowski JA, DelRosso LM, Koo BB, Scharf MT, Sharon D, Zak RS, Kazmi U, Carandang G, Falck-Ytter Y, Shelgikar AV, Trotti LM, Walters AS. J Clin Sleep Med. 2025 Jan 1. PMID: 39324664.
• Patient Insights on Integrating Sleep Apnea Testing into Routine Stroke and TIA Care.Rattray NA, Story KM, Burrone L, Sexson AE, Koo BB, Bravata DM, Perkins AJ, Myers L, Daggy JK, Taylor SE, Fields BG, Kunisaki KM, Daley J, Palacio S, Hermann LD, Sico JJ. J Patient Exp. 2024; 2024 Dec 29. PMID: 39742072.
• The Melanocortin and Endorphin Neuropeptides in Patients with Restless Legs Syndrome.Koo BB, Abdelfattah A, Eysa A, Lu L. Ann Neurol. 2024 Apr; 2024 Feb 3. PMID: 38308537.
• Association of Periodic Limb Movements and Obstructive Sleep Apnea With Risk of Cardiovascular Disease and Mortality.Zinchuk A, Srivali N, Qin L, Jeon S, Ibrahim A, Sands SA, Koo B, Yaggi HK. J Am Heart Assoc. 2024 Feb 6; 2024 Jan 19. PMID: 38240208.
• Review of the role of the endogenous opioid and melanocortin systems in the restless legs syndrome.Walters AS, Li Y, Koo BB, Ondo WG, Weinstock LB, Champion D, Afrin LB, Karroum EG, Bagai K, Spruyt K. Brain. 2024 Jan 4. PMID: 37633259.
• Can tonic motor activation be the magical elixir for restless legs syndrome?Andrew Berkowski J, Koo BB. Sleep. 2023 Oct 11. PMID: 37671678.
• Development and validation of a model predicting mild stroke severity on admission using electronic health record data.Waddell KJ, Myers LJ, Perkins AJ, Sico JJ, Sexson A, Burrone L, Taylor S, Koo B, Daggy JK, Bravata DM. J Stroke Cerebrovasc Dis. 2023 Sep; 2023 Jul 18. PMID: 37473533.
• You too can increase brain iron to treat restless legs syndrome.Koo BB. Sleep. 2023 Aug 14. PMID: 37419490.
• Differential impact of resilience on demoralization and depression in Parkinson disease.de Figueiredo JM, Zhu B, Patel AS, Kohn R, Koo BB, Louis ED. Front Psychiatry. 2023; 2023 Jul 24. PMID: 37559912.
• Impact of the coronavirus disease-2019 pandemic on Veterans Health Administration Sleep Services.Sico JJ, Koo BB, Perkins AJ, Burrone L, Sexson A, Myers LJ, Taylor S, Yarbrough WC, Daggy JK, Miech EJ, Bravata DM. SAGE Open Med. 2023; 2023 May 3. PMID: 37152838.
• Urges to Move and Other Motivation States for Physical Activity in Clinical and Healthy Populations: A Scoping Review Protocol.Stults-Kolehmainen MA, Blacutt M, Bartholomew JB, Boullosa D, Janata P, Koo BB, McKee PC, Casper R, Budnick CJ, Gilson TA, Blakemore RL, Filgueiras A, Williamson SL, SantaBarbara N, Barker JL, Bueno FA, Heldring J, Ash GI. Front Psychol. 2022; 2022 Jul 11. PMID: 35898999.
• Re-equip with opioids instead of dopamine agonists for the treatment of augmentation.Koo BB. Sleep. 2022 Jul 11. PMID: 35556146.
• From Perceived Stress to Demoralization in Parkinson Disease: A Path Analysis.de Figueiredo JM, Zhu B, Patel A, Kohn R, Koo BB, Louis ED. Front Psychiatry. 2022; 2022 May 10. PMID: 35619612.
• Diagnostic and Treatment Considerations in Restless Legs Syndrome Complicated by Diabetic Neuropathy.Garg A, Chilakamarri P, Koo BB. Curr Diab Rep. 2021 Dec 24; 2021 Dec 24. PMID: 34950962.
• Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of Life.Grinberg AS, Best RD, Min KM, Schindler EAD, Koo BB, Sico JJ, Seng EK. Curr Pain Headache Rep. 2021 Oct 19; 2021 Oct 19. PMID: 34668084.
• The Management of Restless Legs Syndrome: An Updated Algorithm.Silber MH, Buchfuhrer MJ, Earley CJ, Koo BB, Manconi M, Winkelman JW. Mayo Clin Proc. 2021 Jul. PMID: 34218864.
• Demoralization predicts suicidality in patients with cluster headache.Koo BB, Bayoumi A, Albanna A, Abusuliman M, Burrone L, Sico JJ, Schindler EAD. J Headache Pain. 2021 Apr 20; 2021 Apr 20. PMID: 33879041.
• Hypothyroidism in restless legs syndrome.Ahmed N, Kandil M, Elfil M, Jamal A, Koo BB. J Sleep Res. 2021 Apr; 2020 Jun 1. PMID: 32483857.
• Restless legs from the urge to reduce gastric acid secretion?Koo BB. Sleep. 2021 Mar 12. PMID: 33709152.
• Impact of Obstructive Sleep Apnea on Cognitive and Motor Functions in Parkinson's Disease.Elfil M, Bahbah EI, Attia MM, Eldokmak M, Koo BB. Mov Disord. 2021 Mar; 2020 Dec 9. PMID: 33296545.
• Demoralization and Quality of Life of Patients with Parkinson Disease.Zhu B, Kohn R, Patel A, Koo BB, Louis ED, de Figueiredo JM. Psychother Psychosom. 2021; 2021 Feb 18. PMID: 33601384.
• Pathophysiologic mechanisms, neuroimaging and treatment in wake-up stroke.Elfil M, Eldokmak M, Baratloo A, Ahmed N, Amin HP, Koo BB. CNS Spectr. 2020 Aug; 2019 Sep 12. PMID: 31511119.
• Implications of the Gut Microbiome in Parkinson's Disease.Elfil M, Kamel S, Kandil M, Koo BB, Schaefer SM. Mov Disord. 2020 Jun; 2020 Feb 24. PMID: 32092186.
• Suicidal risk and demoralization in Parkinson disease.Elfil M, Ahmed N, Alapati A, Bahekar R, Kandil M, Kim C, Schaefer S, Tinaz S, Patel AS, de Figueiredo JM, Louis ED, Koo BB. J Neurol. 2020 Apr; 2019 Dec 4. PMID: 31802218.
• Demoralization in essential tremor: prevalence, clinical correlates, and dissociation from tremor severity.Cersonsky TEK, Kellner S, Morgan S, Cosentino S, Koo BB, de Figueiredo JM, Louis ED. CNS Spectr. 2020 Feb. PMID: 30940264.
• Association of novel measures of sleep disturbances with blood pressure: the Multi-Ethnic Study of Atherosclerosis.Kim JS, Azarbarzin A, Wang R, Djonlagic IE, Punjabi NM, Zee PC, Koo BB, Soliman EZ, Younes M, Redline S. Thorax. 2020 Jan; 2019 Aug 22. PMID: 31439722.
• Associations Between Sleep Apnea and Subclinical Carotid Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis.Zhao YY, Javaheri S, Wang R, Guo N, Koo BB, Stein JH, Korcarz CE, Redline S. Stroke. 2019 Dec; 2019 Oct 15. PMID: 31610764.
• Individual periodic limb movements with arousal are temporally associated with nonsustained ventricular tachycardia: a case-crossover analysis.May AM, May RD, Bena J, Wang L, Monahan K, Stone KL, Barrett-Connor E, Koo BB, Winkelman JW, Redline S, Mittleman MA, Mehra R. Sleep. 2019 Oct 21. PMID: 31585012.
• Suicidal thought and behavior in individuals with restless legs syndrome.Para KS, Chow CA, Nalamada K, Kakade VM, Chilakamarri P, Louis ED, Koo BB. Sleep Med. 2019 Feb; 2018 Oct 11. PMID: 30529070.
• Polysomnography Utilization in Veterans Presenting Acutely with Ischemic Stroke or Transient Ischemic Attack.Koo BB, Sico JJ, Myers LJ, Perkins AJ, Levine D, Miech EJ, Damush TM, Rattray N, Homoya B, Ferguson J, Myers J, Zhang Y, Bravata DM. Cerebrovasc Dis. 2019; 2019 Nov 13. PMID: 31722335.
• Periodic Limb Movements During Sleep Are Not Associated With Hypertension in a Clinical Cohort of Korean Adults.Shin DS, Yang KI, Kim DE, Hwangbo Y, Koo BB, Cho YW. Am J Hypertens. 2018 Oct 15. PMID: 30032284.
• Restless legs syndrome and periodic limb movements during sleep in the Multi-Ethnic Study of Atherosclerosis.Doan TT, Koo BB, Ogilvie RP, Redline S, Lutsey PL. Sleep. 2018 Aug 1. PMID: 29860522.
• Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea.Zinchuk A, Edwards BA, Jeon S, Koo BB, Concato J, Sands S, Wellman A, Yaggi HK. J Clin Sleep Med. 2018 May 15; 2018 May 15. PMID: 29734986.
• Demoralization in Parkinson disease.Koo BB, Chow CA, Shah DR, Khan FH, Steinberg B, Derlein D, Nalamada K, Para KS, Kakade VM, Patel AS, de Figueiredo JM, Louis ED. Neurology. 2018 May 1; 2018 Apr 4. PMID: 29618626.
• Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea.Zinchuk AV, Jeon S, Koo BB, Yan X, Bravata DM, Qin L, Selim BJ, Strohl KP, Redeker NS, Concato J, Yaggi HK. Thorax. 2018 May; 2017 Sep 21. PMID: 28935698.
• Factors affecting fatigue severity in patients with obstructive sleep apnea.Kim SA, Koo BB, Kim DE, Hwangbo Y, Yang KI. Clin Respir J. 2017 Nov; 2017 Aug 14. PMID: 28776933.
• Blunted rise in brain glucose levels during hyperglycemia in adults with obesity and T2DM.Hwang JJ, Jiang L, Hamza M, Sanchez Rangel E, Dai F, Belfort-DeAguiar R, Parikh L, Koo BB, Rothman DL, Mason G, Sherwin RS. JCI Insight. 2017 Oct 19; 2017 Oct 19. PMID: 29046482.
• Iron, dopamine, genetics, and hormones in the pathophysiology of restless legs syndrome.Khan FH, Ahlberg CD, Chow CA, Shah DR, Koo BB. J Neurol. 2017 Aug; 2017 Feb 24. PMID: 28236139.
• Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance.Ferri R, Koo BB, Picchietti DL, Fulda S. Sleep Med. 2017 Mar; 2016 Oct 5. PMID: 28341521.
• Mood Symptoms and Restless Legs Syndrome Without Periodic Limb Movements During Sleep: Is it a Clinical Subtype?Lee HB, Song ML, Koo BB, Cho YW. J Neuropsychiatry Clin Neurosci. 2017 Winter; 2016 Jul 15. PMID: 27417069.
• Restless Legs Syndrome and Depression: Effect Mediation by Disturbed Sleep and Periodic Limb Movements.Koo BB, Blackwell T, Lee HB, Stone KL, Louis ED, Redline S. Am J Geriatr Psychiatry. 2016 Nov; 2016 Apr 27. PMID: 27526989.
• Longitudinal relationships of periodic limb movements during sleep and incident atrial fibrillation.May AM, Blackwell T, Stone KL, Cawthon PM, Sauer WH, Varosy PD, Redline S, Koo BB, Mehra R. Sleep Med. 2016 Sep; 2016 Sep 3. PMID: 27823721.
• Restless Legs Syndrome: Current Concepts about Disease Pathophysiology.Koo BB, Bagai K, Walters AS. Tremor Other Hyperkinet Mov (N Y). 2016; 2016 Jul 22. PMID: 27536462.
• The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.Selim BJ, Koo BB, Qin L, Jeon S, Won C, Redeker NS, Lampert RJ, Concato JP, Bravata DM, Ferguson J, Strohl K, Bennett A, Zinchuk A, Yaggi HK. J Clin Sleep Med. 2016 Jun 15; 2016 Jun 15. PMID: 26951420.
• Erratum to: The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods.Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. Sleep Breath. 2016 May. PMID: 26971325.
• The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods.Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. Sleep Breath. 2016 May; 2015 Dec 7. PMID: 26642771.
• Restless Leg Syndrome Across the Globe: Epidemiology of the Restless Legs Syndrome/Willis-Ekbom Disease.Koo BB. Sleep Med Clin. 2015 Sep; 2015 Jun 20. PMID: 26329429.
• Restless Legs Syndrome: Would You Like That with Movements or Without?Koo BB. Tremor Other Hyperkinet Mov (N Y). 2015; 2015 Jul 1. PMID: 26175956.
• Obstructive apnea with pseudo-Cheyne-Stokes breathing.Yang KI, Kim DE, Koo BB. Sleep Med. 2015 Jul; 2015 May 18. PMID: 26047891.
• Quality measures for the care of adult patients with restless legs syndrome.Trotti LM, Goldstein CA, Harrod CG, Koo BB, Sharon D, Zak R, Chervin RD. J Clin Sleep Med. 2015 Mar 15; 2015 Mar 15. PMID: 25700882.
• Periodic limb movements during sleep and prevalent hypertension in the multi-ethnic study of atherosclerosis.Koo BB, Sillau S, Dean DA 2nd, Lutsey PL, Redline S. Hypertension. 2015 Jan; 2014 Oct 6. PMID: 25287399.