2023
Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center
Grechukhina O, Lipkind H, Lundsberg L, Merriam A, Raab C, Leon-Martinez D, Campbell K. Severe Maternal Morbidity Review and Preventability Assessment in a Large Academic Center. Obstetrics And Gynecology 2023, 141: 857-860. PMID: 36897178, DOI: 10.1097/aog.0000000000005116.Peer-Reviewed Original ResearchConceptsSevere maternal morbiditySystem-level factorsYale-New Haven HospitalRetrospective cohort studyHealth careDetailed case reviewLarge academic centerSMM ratesMaternal morbidityCohort studyPreventability assessmentPreventable causeSMM casesMorbidity reviewAmerican CollegeAcademic centersConsensus criteriaCase reviewPractice changeCareCauseMorbidityHemorrhagePreventabilityReview
2022
Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report
Ackerman-Banks C, Fardelmann K, Lam D, Simmons M, Elder R, Matouk C, Campbell K. Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report. A&A Practice 2022, 16: e01634. PMID: 36599040, DOI: 10.1213/xaa.0000000000001634.Peer-Reviewed Case Reports and Technical NotesConceptsGalen malformationMaternal veinPregnant patientsCesarean deliveryNeuraxial analgesiaTerm neonatesAnesthetic managementHeart failureCardiac failureVentricular dilationIntracranial hemorrhageCase reportCare centerDevelopmental delayPatientsPregnancyLesionsMalformationsVeinUnrepaired lesionsDeliveryAnalgesiaEmbolizationHemorrhageNeonates
2020
SARS-CoV-2 infection of the placenta
Hosier H, Farhadian SF, Morotti RA, Deshmukh U, Lu-Culligan A, Campbell KH, Yasumoto Y, Vogels C, Casanovas-Massana A, Vijayakumar P, Geng B, Odio CD, Fournier J, Brito AF, Fauver JR, Liu F, Alpert T, Tal R, Szigeti-Buck K, Perincheri S, Larsen C, Gariepy AM, Aguilar G, Fardelmann KL, Harigopal M, Taylor HS, Pettker CM, Wyllie AL, Dela Cruz CS, Ring AM, Grubaugh ND, Ko AI, Horvath TL, Iwasaki A, Reddy UM, Lipkind HS. SARS-CoV-2 infection of the placenta. Journal Of Clinical Investigation 2020, 130: 4947-4953. PMID: 32573498, PMCID: PMC7456249, DOI: 10.1172/jci139569.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAbortion, TherapeuticAbruptio PlacentaeAdultBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansMicroscopy, Electron, TransmissionPandemicsPhylogenyPlacentaPneumonia, ViralPre-EclampsiaPregnancyPregnancy Complications, InfectiousPregnancy Trimester, SecondRNA, ViralSARS-CoV-2Viral LoadConceptsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2SARS-CoV-2 infectionRespiratory syndrome coronavirus 2SARS-CoV-2 invasionMaternal antibody responseSymptomatic COVID-19Second trimester pregnancySyndrome coronavirus 2Coronavirus disease 2019Materno-fetal interfaceDense macrophage infiltratesPlacental abruptionSevere preeclampsiaMacrophage infiltratesSevere morbidityTrimester pregnancyPregnant womenCoronavirus 2Antibody responseBackgroundThe effectsDisease 2019Histological examinationImmunohistochemical assaysPlacentaConsolidation of obstetric services in a public health emergency
Campbell KH, Pettker CM, Goffman D. Consolidation of obstetric services in a public health emergency. Seminars In Perinatology 2020, 44: 151281. PMID: 32814629, PMCID: PMC7374143, DOI: 10.1016/j.semperi.2020.151281.Peer-Reviewed Original ResearchCoronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection
Campbell KH, Tweet MS. Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection. Clinical Obstetrics & Gynecology 2020, 63: 852-867. PMID: 32701519, PMCID: PMC10767871, DOI: 10.1097/grf.0000000000000558.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionSpontaneous coronary artery dissectionCoronary artery dissectionArtery dissectionMyocardial infarctionPregnancy-associated acute myocardial infarctionPregnancy-related maternal mortalityManagement of AMIMaternal cardiac deathsCoronary vasospasmNonatherosclerotic etiologyMaternal outcomesCardiac deathCoronary diseaseMultidisciplinary carePregnancy resultsMorbidity rateCoronary arteryMaternal mortalityGlobal improvementSubstantial proportionInfarctionPregnancyEtiologyPhysiological changesPrevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut
Campbell KH, Tornatore JM, Lawrence KE, Illuzzi JL, Sussman LS, Lipkind HS, Pettker CM. Prevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut. JAMA 2020, 323: 2520-2522. PMID: 32453390, PMCID: PMC7251498, DOI: 10.1001/jama.2020.8904.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsymptomatic DiseasesBetacoronavirusClinical Laboratory TechniquesConnecticutCoronavirus InfectionsCOVID-19COVID-19 TestingDelivery, ObstetricFemaleHumansInfectious Disease Transmission, Patient-to-ProfessionalPandemicsParturitionPersonal Protective EquipmentPneumonia, ViralPregnancyPregnancy Complications, InfectiousPrevalenceSARS-CoV-2
2019
Evaluating the Impact of a New Smartphone Texting Tool on Patient Care in Obstetrics, an Emergent Healthcare Setting
Feinberg J, Shaw S, Kashyap N, Illuzzi J, Campbell K, Hsiao A, Pettker C. Evaluating the Impact of a New Smartphone Texting Tool on Patient Care in Obstetrics, an Emergent Healthcare Setting. Applied Clinical Informatics 2019, 10: 879-887. PMID: 31747710, PMCID: PMC6867929, DOI: 10.1055/s-0039-1700868.Peer-Reviewed Original ResearchConceptsPatient careText messaging systemEmergent settingSustained improvementYale-New Haven HospitalPoor patient outcomesTimely evaluationNurses' knowledgePatient outcomesTexting systemDecrease riskNew Health Insurance PortabilityHealthcare settingsObstetricsCareHealth Insurance PortabilityWhitney testHospitalClinical workflowMonthsWilcoxon-MannOpen-ended questionsInsurance PortabilityLikert scalePotential benefitsSevere maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort
Lipkind H, Zuckerwise L, Turner E, Collins J, Campbell K, Reddy U, Illuzi J, Merriam A. Severe maternal morbidity during delivery hospitalisation in a large international administrative database, 2008–2013: a retrospective cohort. BJOG An International Journal Of Obstetrics & Gynaecology 2019, 126: 1223-1230. PMID: 31100201, DOI: 10.1111/1471-0528.15818.Peer-Reviewed Original ResearchMeSH KeywordsAdultAustraliaCenters for Disease Control and Prevention, U.S.ComorbidityDatabases, FactualEnglandFemaleHospitalizationHumansMaternal AgeMaternal DeathMiddle AgedObstetric Labor ComplicationsPregnancyPregnancy ComplicationsPregnancy OutcomeRetrospective StudiesRisk FactorsUnited StatesYoung AdultConceptsSevere maternal morbidityMaternal morbidityDelivery hospitalisationRetrospective cohortRisk factorsSevere maternal morbidity ratesMaternal morbidity ratesAcute renal failureLife-threatening diagnosisAdvanced maternal ageLife-saving procedureLarge university hospitalChi-square testMorbidity variesPregnancy complicationsClinical characteristicsIntravascular coagulationRenal failureSevere morbidityMultivariable analysisMorbidity rateAdverse outcomesClinical differencesMaternal ageUniversity HospitalSevere cardiovascular morbidity in women with hypertensive diseases during delivery hospitalization
Ackerman CM, Platner MH, Spatz ES, Illuzzi JL, Xu X, Campbell KH, Smith GN, Paidas MJ, Lipkind HS. Severe cardiovascular morbidity in women with hypertensive diseases during delivery hospitalization. American Journal Of Obstetrics And Gynecology 2019, 220: 582.e1-582.e11. PMID: 30742823, DOI: 10.1016/j.ajog.2019.02.010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCardiomyopathiesCardiovascular DiseasesCerebrovascular DisordersCohort StudiesEclampsiaEducational StatusElectric CountershockEthnicityFemaleHeart ArrestHeart FailureHospitalizationHumansHypertension, Pregnancy-InducedInformation Storage and RetrievalInsurance, HealthLogistic ModelsMiddle AgedMultivariate AnalysisMyocardial InfarctionNew York CityObesity, MaternalPovertyPre-EclampsiaPregnancyRetrospective StudiesSeverity of Illness IndexVentricular FibrillationYoung AdultConceptsSevere cardiovascular morbidityCardiovascular morbidityDelivery hospitalizationsHypertensive disordersSevere featuresNormotensive womenGestational hypertensionCardiovascular diseaseRetrospective cohort studyClinical risk factorsPregnancy-related deathsMultivariable logistic regressionChronic hypertensionDiligent screeningSingleton gestationsCohort studyHypertensive diseaseDiabetes mellitusMaternal deathsRisk factorsInclusion criteriaDiseases-10HospitalizationMorbidityPreeclampsia
2018
Hospital variation in utilization and success of trial of labor after a prior cesarean
Xu X, Lee HC, Lin H, Lundsberg LS, Campbell KH, Lipkind HS, Pettker CM, Illuzzi JL. Hospital variation in utilization and success of trial of labor after a prior cesarean. American Journal Of Obstetrics And Gynecology 2018, 220: 98.e1-98.e14. PMID: 30278176, DOI: 10.1016/j.ajog.2018.09.034.Peer-Reviewed Original ResearchMeSH KeywordsAdultCaliforniaCesarean SectionCohort StudiesDatabases, FactualFemaleGestational AgeHospitals, High-VolumeHospitals, Low-VolumeHumansInfant, NewbornMaternal AgePatient SafetyPregnancyPregnancy OutcomeRetrospective StudiesRisk AssessmentTrial of LaborUterine RuptureVaginal Birth after CesareanConceptsSuccess of trialCesarean deliveryTrial of laborHospital variationSuccess rateLow success rateNewborn hospital discharge recordsPatient clinical risk factorsSevere unexpected newborn complicationsNewborn respiratory complicationsUnexpected newborn complicationsClinical risk factorsPrior cesarean deliveryHospital discharge recordsPatient case mixBirth certificate dataMidwife-attended birthsAnesthesia availabilityNewborn infectionRespiratory complicationsUterine ruptureNewborn morbidityPrior cesareanNewborn complicationsVaginal birthOptimal maternal and neonatal outcomes and associated hospital characteristics
Campbell KH, Illuzzi JL, Lee HC, Lin H, Lipkind HS, Lundsberg LS, Pettker CM, Xu X. Optimal maternal and neonatal outcomes and associated hospital characteristics. Birth 2018, 46: 289-299. PMID: 30251270, DOI: 10.1111/birt.12400.Peer-Reviewed Original ResearchMeSH KeywordsAdultBirth CertificatesCaliforniaCesarean SectionFemaleGestational AgeHospitalsHumansInfant, NewbornInfant, Newborn, DiseasesMorbidityObstetric Labor ComplicationsObstetricsPatient DischargePoisson DistributionPregnancyQuality Indicators, Health CareRegression AnalysisRisk FactorsYoung AdultConceptsRisk-standardized ratesMorbidity rateNeonatal outcomesObstetrical performancePatient clinical risk factorsFuture quality improvement effortsMaternal morbidity ratesNeonatal morbidity ratesProcedures/surgeriesSevere newborn morbiditySevere maternal morbidityClinical risk factorsShock/resuscitationHospital discharge recordsMaternal-newborn outcomesQuality improvement effortsPrevalent morbidityMaternal morbidityNeonatal morbidityRespiratory complicationsIntravascular coagulationNewborn morbidityHeart failureTerm birthsHospital variation
2013
Maternal Morbidity and Risk of Death at Delivery Hospitalization
Campbell KH, Savitz D, Werner EF, Pettker CM, Goffman D, Chazotte C, Lipkind HS. Maternal Morbidity and Risk of Death at Delivery Hospitalization. Obstetrics And Gynecology 2013, 122: 627-633. PMID: 23921870, DOI: 10.1097/aog.0b013e3182a06f4e.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusDelivery hospitalizationsRisk of deathChronic hypertensionMaternal morbidityPulmonary hypertensionMaternal mortalityPregestational diabetesMaternal deathsNon-Hispanic black ethnicityGestational diabetes mellitusHospital discharge diagnosisChronic lung diseasePrimary cesarean deliverySingleton live birthsWeeks of gestationChronic cardiovascular diseaseMultivariate logistic regressionEntire study populationMaternal diseaseMaternal obesityPremature deliveryPrepregnancy weightCesarean deliveryDiabetes mellitus
2012
Comparative Analysis of 2-D Versus 3-D Ultrasound Estimation of the Fetal Adrenal Gland Volume and Prediction of Preterm Birth
Turan O, Turan S, Buhimschi I, Funai E, Campbell K, Bahtiyar O, Harman C, Copel J, Baschat A, Buhimschi C. Comparative Analysis of 2-D Versus 3-D Ultrasound Estimation of the Fetal Adrenal Gland Volume and Prediction of Preterm Birth. American Journal Of Perinatology 2012, 29: 673-680. PMID: 22644825, PMCID: PMC3838705, DOI: 10.1055/s-0032-1314887.Peer-Reviewed Original Research