2020
George A. Beller, MD (Born 1940)
Wackers FJT, Corner T. George A. Beller, MD (Born 1940). Journal Of Nuclear Cardiology 2020, 27: 723-725. PMID: 32367225, DOI: 10.1007/s12350-020-02115-2.Peer-Reviewed Original Research
2008
Utility of Cardiac Biomarkers in Predicting Infarct Size, Left Ventricular Function, and Clinical Outcome After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction
Chia S, Senatore F, Raffel O, Lee H, Wackers F, Jang I. Utility of Cardiac Biomarkers in Predicting Infarct Size, Left Ventricular Function, and Clinical Outcome After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. JACC Cardiovascular Interventions 2008, 1: 415-423. PMID: 19463339, DOI: 10.1016/j.jcin.2008.04.010.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBenzenesulfonatesBiomarkersCardiovascular AgentsCoronary AngiographyCreatine Kinase, MB FormDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionMyocardiumPiperazinesPredictive Value of TestsProportional Hazards ModelsProspective StudiesRisk AssessmentStroke VolumeTime FactorsTomography, Emission-Computed, Single-PhotonTreatment OutcomeTroponin ITroponin TUnited StatesVentricular Function, LeftConceptsST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionPrimary PCIElevation myocardial infarctionPercutaneous coronary interventionInfarct sizeClinical outcomesMyocardial infarctionCardiac biomarkersCoronary interventionCreatine kinaseCK-MBLarge ST-segment elevation myocardial infarctionTroponin TIntracellular calcium modulatorsLarger infarct sizeVentricular ejection fractionCardiac biomarker levelsLeft ventricular functionComposite clinical eventsTime-concentration curveEVOLVE trialLower LVEFAdverse eventsEjection fraction
2006
Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging
Papaioannou GI, Kasapis C, Seip RL, Grey NJ, Katten D, Wackers FJ, Inzucchi SE, Engel S, Taylor A, Young LH, Chyun DA, Davey JA, Iskandrian AE, Ratner RE, Robinson EC, Carolan S, Heller GV. Value of peripheral vascular endothelial function in the detection of relative myocardial ischemia in asymptomatic type 2 diabetic patients who underwent myocardial perfusion imaging. Journal Of Nuclear Cardiology 2006, 13: 362-368. PMID: 16750781, DOI: 10.1016/j.nuclcard.2006.01.022.Peer-Reviewed Original ResearchConceptsEndothelium-dependent vasodilationEndothelium-independent vasodilationCoronary artery diseaseMyocardial perfusion imagingRelative myocardial ischemiaAsymptomatic patientsEndothelial functionNegative predictive valueMyocardial ischemiaAsymptomatic type 2 diabetic patientsExclusion of CADPredictive valueAdenosine myocardial perfusion imagingPeripheral vascular endothelial functionType 2 diabetic patientsType 2 diabetes mellitusHigh negative predictive valueAsymptomatic Diabetics (DIAD) studyBrachial artery ultrasonographyVascular endothelial functionDetection of ischemiaEDV responseRelative ischemiaEndothelial dysfunctionOvert atherosclerosis
2003
Electromechanical mapping for detecting myocardial viability and ischemia in patients with severe ischemic cardiomyopathy
Samady H, Liu Y, Choi CJ, Ragosta M, Pfau SE, Cleman MW, Powers ER, Kramer CM, Wackers F, Beller GA, Watson DD. Electromechanical mapping for detecting myocardial viability and ischemia in patients with severe ischemic cardiomyopathy. The American Journal Of Cardiology 2003, 91: 807-811. PMID: 12667565, DOI: 10.1016/s0002-9149(03)00013-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedBody Surface Potential MappingCardiomyopathiesCell SurvivalElectrophysiologic Techniques, CardiacFemaleHumansMaleMiddle AgedMyocardial IschemiaMyocardiumPredictive Value of TestsRadiopharmaceuticalsRestROC CurveSensitivity and SpecificitySeverity of Illness IndexStatistics as TopicStress, PhysiologicalStroke VolumeTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftConceptsSevere ischemic cardiomyopathyIschemic cardiomyopathyViable myocardiumMyocardial viabilityDipyridamole single-photon emissionUnipolar voltageDysfunctional myocardial segmentsBipolar voltageSingle photon emissionDipyridamole SPECTDipyridamole technetiumQuantitative technetiumInducible ischemiaNonviable segmentsNonviable myocardiumElectromechanical mappingMyocardial segmentsTracer uptakePatientsViable segmentsLogistic regressionCardiomyopathyMyocardiumIschemiaSPECT
1998
Nonperfusion applications in nuclear cardiology: Report of a task force of the American society of nuclear cardiology
DePuey E, Port S, Wackers F, Rozanski A, Botvinick E, Dae M, Tamaki N. Nonperfusion applications in nuclear cardiology: Report of a task force of the American society of nuclear cardiology. Journal Of Nuclear Cardiology 1998, 5: 218-231. PMID: 9588675, DOI: 10.1016/s1071-3581(98)90206-9.Peer-Reviewed Original Research
1997
Relationship of scar and ischemia to the results of programmed electrophysiological stimulation in patients with coronary artery disease
Gradel C, Jain D, Batsford W, Wackers F, Zaret B. Relationship of scar and ischemia to the results of programmed electrophysiological stimulation in patients with coronary artery disease. Journal Of Nuclear Cardiology 1997, 4: 379-386. PMID: 9362014, DOI: 10.1016/s1071-3581(97)90029-5.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseMyocardial perfusion imagingSustained ventricular tachycardiaPerfusion defect sizeVentricular tachycardiaElectrophysiological studiesArtery diseaseIndependent predictorsMultivariate analysisChronic coronary artery diseaseLeft ventricular ejection fractionSustained monomorphic ventricular tachycardiaGlobal left ventricular functionVentricular ejection fractionLeft ventricular functionPrevious myocardial infarctionMonomorphic ventricular tachycardiaBest independent predictorSize of ischemiaAdditional ischemiaArrhythmia historyInducible patientsNoninducible patientsSize of scarClinical predictors
1996
Radionuclide detection of myocardial ischemia and myocardial viability: Is the glass half empty or half full?
Wackers F. Radionuclide detection of myocardial ischemia and myocardial viability: Is the glass half empty or half full? Journal Of The American College Of Cardiology 1996, 27: 1598-1600. PMID: 8636542, DOI: 10.1016/0735-1097(96)00101-5.Peer-Reviewed Original Research
1995
Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study.
Soufer R, Dey H, Lawson A, Wackers F, Zaret B. Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study. Journal Of Nuclear Medicine 1995, 36: 180-7. PMID: 7830110.Peer-Reviewed Original ResearchConceptsPlanar thallium scintigraphyCardiac eventsThallium scintigraphyReverse redistributionChronic coronary artery diseasePET viabilityAbnormal regional wall motionPlanar thallium imagesMyocardial Infarction trialPercent of patientsFuture cardiac eventsFuture cardiovascular eventsCoronary artery diseaseFavorable clinical outcomeMyocardial metabolic activityRegional wall motion analysisRegional wall motionPercent of segmentsWall motion analysisPET criteriaCardiovascular eventsReperfusion therapyArtery diseaseClinical outcomesPrognostic value
1991
Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest
Kayden D, Sigal S, Soufer R, Mattera J, Zaret B, Wackers F. Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest. Journal Of The American College Of Cardiology 1991, 18: 1480-1486. PMID: 1939949, DOI: 10.1016/0735-1097(91)90678-3.Peer-Reviewed Original ResearchConceptsInjection of thalliumRedistribution imagesDefect reversibilityThallium-201 reinjectionThallium-201 defectsLate redistribution imagingPoor quality studiesDiagnostic informationClinical variablesRedistribution imagingThallium defectsThallium imagesMyocardial viabilityReversible defectsStress imagingThallium-201PatientsBetter diagnostic informationStress testingExercisePresent studyQuality studiesInjectionLate redistributionReinjection
1989
Heterogeneous signal intensity in magnetic resonance images of hypertrophied left ventricular myocardium
Zahler R, Chelmow D, Gore J, Wilkens K, Pope C, Sostman H, Meese R, Negro-Vilar R, Herfkens R, Wackers F, Zaret B. Heterogeneous signal intensity in magnetic resonance images of hypertrophied left ventricular myocardium. Magnetic Resonance Imaging 1989, 7: 517-528. PMID: 2532699, DOI: 10.1016/0730-725x(89)90405-0.Peer-Reviewed Original ResearchConceptsLeft ventricular hypertrophyVentricular hypertrophyLeft ventricular hypertrophy patientsHypertrophy patientsMagnetic resonance imagesHuman left ventricular hypertrophyDuration of diseaseCongestive heart failureHeterogeneous signal intensityLeft ventricular myocardiumMagnetic resonance imagingResonance imagesElectrocardiographic abnormalitiesHeart failureAortic bandingPathologic changesHypertrophied myocardiumEnd-diastolic imagesVentricular myocardiumPatientsHypertrophyResonance imagingEnd-systolic imagesNormal tissuesTissue characterization algorithm
1988
The Role of Nuclear Cardiology in Assessment of Acute Myocardial Infarction
den D, Wackers F, Zaret B. The Role of Nuclear Cardiology in Assessment of Acute Myocardial Infarction. Cardiology Clinics 1988, 6: 81-95. PMID: 3048676, DOI: 10.1016/s0733-8651(18)30503-4.Peer-Reviewed Original ResearchConceptsConvalescent phaseVentricular functionExercise-induced ischemiaAcute myocardial infarctionSalvaged myocardiumThallium imagingThrombolytic therapyAcute interventionIschemic myocardiumMyocardial infarctionPrognostic informationFurther interventionMyocardial perfusionPerfusion imagingAmbulatory monitoringMetabolic imagingMyocardiumNuclear cardiologyAppropriate management strategiesInterventionImagingInfarctionIschemiaPatientsTherapy
1987
Usefulness of residual ischemic myocardium within prior infarct zone for identifying patients at high risk late after acute myocardial infarction
Brown K, Weiss R, Clements J, Wackers F. Usefulness of residual ischemic myocardium within prior infarct zone for identifying patients at high risk late after acute myocardial infarction. The American Journal Of Cardiology 1987, 60: 15-19. PMID: 3604929, DOI: 10.1016/0002-9149(87)90975-1.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionTI-201 redistributionCardiac eventsInfarct zoneMyocardial infarctionStepwise multivariate logistic regression analysisPrior acute myocardial infarctionAngiographic coronary artery diseaseMultivariate logistic regression analysisIschemic viable myocardiumResidual ischemic myocardiumTotal cardiac eventsCoronary artery diseaseThallium-201 imagingSignificant predictorsLogistic regression analysisOnly significant predictorCoronary revascularizationChest painArtery diseaseCardiac catheterizationConsecutive patientsPrognostic implicationsViable myocardiumIschemic myocardium
1984
Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation
Sinusas A, Hardin N, Clements J, Wackers F. Pathoanatomic correlates of regional left ventricular wall motion assessed by equilibrium radionuclide angiocardiography: A postmortem correlation. The American Journal Of Cardiology 1984, 54: 975-981. PMID: 6496360, DOI: 10.1016/s0002-9149(84)80128-9.Peer-Reviewed Original ResearchConceptsAbnormal regional wall motionRegional wall motionPostmortem findingsPathoanatomic correlatesEquilibrium radionuclideLeft bundle branch blockNormal regional wall motionGross myocardial lesionsLeft ventricular wall motionBundle branch blockLeft ventricular segmentsRegional left ventricular wall motionVentricular wall motionFalse-negative segmentsCoronary arterySevere stenosisMyocardial infarctionNontransmural infarctionBranch blockVentricular segmentsWall motionMyocardial lesionsPatientsPredictive valueAbnormal segments
1976
Coronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction.
Wackers F, Lie K, Becker A, Durrer D, Wellens H. Coronary artery disease in patients dying from cardiogenic shock or congestive heart failure in the setting of acute myocardial infarction. Heart 1976, 38: 906. PMID: 971375, PMCID: PMC483104, DOI: 10.1136/hrt.38.9.906.Peer-Reviewed Original ResearchConceptsCongestive heart failureAcute myocardial infarctionHeart failureCardiogenic shockCoronary arteryMyocardial infarctionSevere diseaseFatal congestive heart failureRefractory congestive heart failurePump failureThree-vessel diseaseCoronary bypass surgeryRight coronary arteryCoronary artery diseaseLeft circumflex arteryCent narrowingBypass surgeryArtery diseaseLeft anteriorCircumflex arteryPathological findingsSevere narrowingEqual incidenceAnatomical findingsPatientsValue and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction
Wackers F, Sokole E, Samson G, Schoot J, Lie K, Liem K, Wellens H. Value and Limitations of Thallium-201 Scintigraphy in the Acute Phase of Myocardial Infarction. New England Journal Of Medicine 1976, 295: 1-5. PMID: 1272283, DOI: 10.1056/nejm197607012950101.Peer-Reviewed Original Research