2007
Flow cytometric analysis of myelomonocytic cells by a pattern recognition approach is sensitive and specific in diagnosing myelodysplastic syndrome and related marrow diseases: Emphasis on a global evaluation and recognition of diagnostic pitfalls
Stachurski D, Smith BR, Pozdnyakova O, Andersen M, Xiao Z, Raza A, Woda BA, Wang A. Flow cytometric analysis of myelomonocytic cells by a pattern recognition approach is sensitive and specific in diagnosing myelodysplastic syndrome and related marrow diseases: Emphasis on a global evaluation and recognition of diagnostic pitfalls. Leukemia Research 2007, 32: 215-224. PMID: 17675229, DOI: 10.1016/j.leukres.2007.06.012.Peer-Reviewed Original ResearchConceptsMyelodysplastic syndromeFlow cytometryDiagnostic pitfallsMyelomonocytic cellsMDS/MPDClonal cytogenetic abnormalitiesGlobal evaluationImmunophenotypic aberranciesRetrospective reviewMorphological dysplasiaMarrow diseaseMyeloproliferative diseaseDiagnostic utilityCytogenetic abnormalitiesDisease casesMyeloid diseasesCytometric analysisOverall sensitivityAbnormalitiesDiseaseOverall abnormalitySyndromeIntermediate category
1994
B-Cell Precursor Bone Marrow Reconstitution After Bone Marrow Transplantation
Leitenberg D, Rappeport J, Smith B. B-Cell Precursor Bone Marrow Reconstitution After Bone Marrow Transplantation. American Journal Of Clinical Pathology 1994, 102: 231-236. PMID: 8042594, DOI: 10.1093/ajcp/102.2.231.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntigens, CDBlotting, SouthernB-LymphocytesBone MarrowBone Marrow CellsBone Marrow TransplantationChildChild, PreschoolClone CellsFemaleFlow CytometryFluorescent Antibody TechniqueGene Rearrangement, B-Lymphocyte, Heavy ChainHematopoietic Stem CellsHumansImmunophenotypingInfantKineticsMaleMiddle AgedNeprilysinConceptsBone marrow transplantationMarrow transplantationB cell subsetsBone marrow reconstitutionB cell precursorsSurface antigenic phenotypeImmature B cellsImmunoglobulin gene rearrangementsHumoral immunodeficiencyMonoclonal gammapathyMarrow reconstitutionAntigenic phenotypeB cellsTransplantationGene rearrangementsMarked increaseLeukemia lymphoblastsCellsPatientsGammapathyImmunodeficiencyMarrowCD34ReconstitutionMonths
1991
Selective Depletion of Bone Marrow T Lymphocytes With Anti-CD5 Monoclonal Antibodies: Effective Prophylaxis for Graft-Versus-Host Disease in Patients With Hematologic Malignancies
Antin J, Bierer B, Smith B, Ferrara J, Guinan E, Sieff C, Golan D, Macklis R, Tarbell N, Lynch E, Reichert T, Blythman H, Bouloux C, Rappeport J, Burakoff S, Weinstein H. Selective Depletion of Bone Marrow T Lymphocytes With Anti-CD5 Monoclonal Antibodies: Effective Prophylaxis for Graft-Versus-Host Disease in Patients With Hematologic Malignancies. Blood 1991, 78: 2139-2149. PMID: 1717080, DOI: 10.1182/blood.v78.8.2139.2139.Peer-Reviewed Original ResearchConceptsAnti-CD5 MoAbHigh-risk patientsGraft failureHost diseaseHematologic malignanciesT cellsEpstein-Barr virus-associated lymphoproliferative disorderBone marrowActuarial event-free survivalBone marrow T lymphocytesAnti-CD5 monoclonal antibodyDiagnosis of myelodysplasiaMarrow T lymphocytesEvent-free survivalLow-risk patientsLate graft failureTotal body irradiationSignificant risk factorsRisk of relapseMajor histocompatibility complexActuarial survivalAcute graftAcute GVHDChronic GVHDEvaluable patients
1990
Retroviral mediated gene transfer into bone marrow progenitor cells: use of beta-galactosidase as a selectable marker
Strair R, Towle M, Smith B. Retroviral mediated gene transfer into bone marrow progenitor cells: use of beta-galactosidase as a selectable marker. Nucleic Acids Research 1990, 18: 4759-4762. PMID: 2118622, PMCID: PMC331937, DOI: 10.1093/nar/18.16.4759.Peer-Reviewed Original ResearchDepletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
Antin JH, Bierer BE, Smith BR, Guinan EC, Provost MM, Ferrara J, Macklis RM, Tarbell NJ, Blythman H, Bouloux C. Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease. Progress In Clinical And Biological Research 1990, 333: 207-15. PMID: 1689852.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibodies, MonoclonalAntigens, CDAntigens, DifferentiationBone MarrowBone Marrow CellsBone Marrow TransplantationCD5 AntigensChildChild, PreschoolCombined Modality TherapyCyclophosphamideCytarabineDrug EvaluationGraft vs Host DiseaseHumansImmunotoxinsLeukemiaMiddle AgedMyelodysplastic SyndromesRicinRisk FactorsT-LymphocytesWhole-Body Irradiation
1989
Hematopoiesis in vitro coexists with natural killer lymphocytes.
Niemeyer C, Sieff C, Smith B, Ault K, Nathan D. Hematopoiesis in vitro coexists with natural killer lymphocytes. Blood 1989, 74: 2376-82. PMID: 2529928, DOI: 10.1182/blood.v74.7.2376.bloodjournal7472376.Peer-Reviewed Original ResearchConceptsBlood NK cellsNatural killerNK cellsInterleukin-2Colony formationMarrow progenitorsInhibition of MyeloidK562 target cellsNatural killer lymphocytesCell populationsCD16 positive lymphocytesMarrow cell populationsPositive lymphocytesHematopoietic progenitor cellsKiller lymphocytesCell ratioProgenitor cell populationsLymphocytesTarget cellsProgenitor cellsCell sorterInhibitionHuman hematopoiesisDisparate findingsCell lineages
1987
Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients.
Daley J, Rozans M, Smith B, Burakoff S, Rappeport J, Miller R. Retarded recovery of functional T cell frequencies in T cell-depleted bone marrow transplant recipients. Blood 1987, 70: 960-4. PMID: 3307954, DOI: 10.1182/blood.v70.4.960.bloodjournal704960.Peer-Reviewed Original ResearchConceptsT cell-depleted bone marrowT cell frequenciesUntreated marrowT cellsBone marrowCell frequencyFunctional T cell compartmentBone marrow transplant recipientsDonor T cellsMonoclonal antibodies Leu-1Marrow transplant recipientsReactive T cellsT cell compartmentT lymphocyte precursorsCompetent T lymphocytesTransplant recipientsMarrow transplantationT lymphocytesLymphocyte precursorsLeu-1Neoplastic cellsMarrowPatientsRecipientsTransplantation