2019
Adaptive Imaging Versus Periodic Surveillance for Intrafraction Motion Management During Prostate Cancer Radiotherapy
Ma X, Yan H, Nath R, Chen Z, Li H, Liu W. Adaptive Imaging Versus Periodic Surveillance for Intrafraction Motion Management During Prostate Cancer Radiotherapy. Technology In Cancer Research & Treatment 2019, 18: 1533033819844489. PMID: 31177934, PMCID: PMC6558533, DOI: 10.1177/1533033819844489.Peer-Reviewed Original ResearchConceptsIntensity-modulated radiation therapyRadiation therapyCouch shiftsAutomatic motion compensationAdaptive imagingAutomatic correctionCurrent clinical situationProstate cancer radiotherapyImaging surveillanceMotion compensationPeriodic imaging surveillanceProstate cancerPeriodic surveillanceClinical situationsSurveillance strategiesBenefits of adaptivePeriodic imagingArc therapyMean percentageTherapyIntrafraction motion managementCancer radiotherapyRadiation therapy simulationTherapy simulationBeam delivery
2010
Response to “Comment on ‘AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137’” [Med. Phys. 36, 5310–5322 (2009)]
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. Response to “Comment on ‘AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137’” [Med. Phys. 36, 5310–5322 (2009)]. Medical Physics 2010, 37: 1933-1933. PMID: 20443515, DOI: 10.1118/1.3358143.Peer-Reviewed Original Research
2009
AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137
Nath R, Bice WS, Butler WM, Chen Z, Meigooni AS, Narayana V, Rivard MJ, Yu Y. AAPM recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer: Report of Task Group 137. Medical Physics 2009, 36: 5310-5322. PMID: 19994539, PMCID: PMC2776817, DOI: 10.1118/1.3246613.Peer-Reviewed Original ResearchConceptsBiological equivalent doseTumor volumeDose prescriptionStandard of careProstate cancer patientsPermanent interstitial brachytherapyAcute single dosesEffects of edemaCancer patientsSurgical traumaIntraoperative implantationSingle dosesClinical trialsProstate cancerRadiobiological modelsCurrent recommendationsInterstitial brachytherapyMore specific guidelinesRoutine patient treatmentsDifferent dose distributionsTreatment planPatient treatmentTarget volumeMost implantsDose distributionTime dependence of energy spectra of brachytherapy sources and its impact on the half and the tenth value layers
Yue NJ, Chen Z, Hearn RA, Rodgers JJ, Nath R. Time dependence of energy spectra of brachytherapy sources and its impact on the half and the tenth value layers. Medical Physics 2009, 36: 5175-5182. PMID: 19994527, DOI: 10.1118/1.3246843.Peer-Reviewed Original Research
2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplants
2004
Development of a rat solid tumor model for continuous low-dose-rate irradiation studies using 125I and 103Pd sources
Nath R, Bongiorni P, Chen Z, Gragnano J, Rockwell S. Development of a rat solid tumor model for continuous low-dose-rate irradiation studies using 125I and 103Pd sources. Brachytherapy 2004, 3: 159-172. PMID: 15533809, DOI: 10.1016/j.brachy.2004.08.004.Peer-Reviewed Original Research
2002
Edema-induced increase in tumour cell survival for 125I and 103Pd prostate permanent seed implants—a bio-mathematical model
Yue N, Chen Z, Nath R. Edema-induced increase in tumour cell survival for 125I and 103Pd prostate permanent seed implants—a bio-mathematical model. Physics In Medicine And Biology 2002, 47: 1185-1204. PMID: 11996063, DOI: 10.1088/0031-9155/47/7/313.Peer-Reviewed Original ResearchConceptsTumor potential doubling timeContinuous low dose rate irradiationTumor cell survivalSeed implantsBio-mathematical modelCell survivalExternal beam radiotherapyPresence of edemaProstate seed implantationLow dose rate irradiationEdema magnitudeEffects of edemaPotential doubling timeTypical edemaDose rate irradiationProstate volumeSurgical traumaPermanent seed implantsSeed implantationSignificant edemaTreatment strategiesSurgical proceduresBeam radiotherapyEdemaDose coverage
1999
Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants
Yue N, Chen Z, Peschel R, Dicker A, Waterman F, Nath R. Optimum timing for image-based dose evaluation of 125I and 103Pd prostate seed implants. International Journal Of Radiation Oncology • Biology • Physics 1999, 45: 1063-1072. PMID: 10571216, DOI: 10.1016/s0360-3016(99)00282-5.Peer-Reviewed Original ResearchConceptsDose-volume histogramsProstate volumeDose coverageConventional dose-volume histogramsSeed implantsEdema magnitudeMagnitude of edemaOptimum timingPostimplant dose-volume histogramDose evaluationOptimal patient managementProstate seed implantationPreimplant planImplant patientsPermanent brachytherapy implantsProstate seed implantsPatient managementProstate cancerSeed implantationSurgical proceduresEdemaProstateDose distributionDays postimplantationPatients