2022
High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study
Mu Z, Palyo R, Goyal D, Sandoval V, Mu Z, Tao Z, Sinusas A, Miller E, Liu Y. High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study. 2022, 00: 1-4. DOI: 10.1109/nss/mic44845.2022.10399016.Peer-Reviewed Original ResearchTc-99m solutionHole imagesCardiac SPECTCardiac phantomMyocardial perfusion defectsField imagesParallel hole collimatorResolution of SPECTSub-endocardiumSubset expectation maximizationCZT detectorsSub-epicardiumHole collimatorPerfusion defectsHigh-resolutionOSEM algorithmCollimatorPhantom studyScanner configurationReconstruction technologyPhantomSPECT slicesTransmural perfusion gradientExpectation maximizationOSEM
2016
SPECT Imaging of 2-D and 3-D Distributed Sources with Near-Field Coded Aperture Collimation: Computer Simulation and Real Data Validation
Mu Z, Dobrucki LW, Liu YH. SPECT Imaging of 2-D and 3-D Distributed Sources with Near-Field Coded Aperture Collimation: Computer Simulation and Real Data Validation. Journal Of Medical And Biological Engineering 2016, 36: 32-43. PMID: 27069461, PMCID: PMC4791458, DOI: 10.1007/s40846-016-0111-6.Peer-Reviewed Original ResearchMaximum likelihood expectation maximizationReconstruction approachImage resolutionLarge projection angleIterative image reconstructionNoise artifactsMicro-SPECT systemComputer simulationsReal data validationImage reconstructionDigital phantomExpectation maximizationData validationCA moduleMLEM algorithmImage qualityPinhole imagesProjection angleCommercial softwareImagesPhantom imagesSquared errorSPECT imagesCA imagesImage contrast