Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM. Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair. Nature Communications 2022, 13: 1875. PMID: 35388011, PMCID: PMC8986845, DOI: 10.1038/s41467-022-29481-4.Peer-Reviewed Original ResearchMeSH KeywordsCalciumCytosolEndosomal Sorting Complexes Required for TransportLysosomesSphingomyelinsConceptsSubsequent metabolic conversion