2024
Post-Translational Regulation of a Bidomain Glycerol-3-Phosphate Dehydrogenase Catalyzing Glycerol Synthesis under Salinity Stress in Chlamydomonas reinhardtii
Cruz-Powell I, Subedi B, Kim Y, Morales-Sánchez D, Cerutti H. Post-Translational Regulation of a Bidomain Glycerol-3-Phosphate Dehydrogenase Catalyzing Glycerol Synthesis under Salinity Stress in Chlamydomonas reinhardtii. Phycology 2024, 4: 213-234. DOI: 10.3390/phycology4020012.Peer-Reviewed Original ResearchGlycerol-3-phosphate dehydrogenaseGlycerol-3-phosphate phosphataseGlycerol-3-phosphateGlycerol synthesisWild typeInhibitor of cytoplasmic protein synthesisPlastid-localized enzymeResponse of microalgaePost-translational regulationTransgenic strainsCytoplasmic protein synthesisSynthesis of glycerolHigh salinityExposure to high salinityCore chlorophytesInhibitors of protein kinasesChlamydomonas reinhardtiiGlycerol accumulationNutrient deprivationGPD2Protein kinaseProtein activityAccumulate glycerolSalt stressEnvironmental stress
2017
A multidomain enzyme, with glycerol‐3‐phosphate dehydrogenase and phosphatase activities, is involved in a chloroplastic pathway for glycerol synthesis in Chlamydomonas reinhardtii
Morales‐Sánchez D, Kim Y, Terng EL, Peterson L, Cerutti H. A multidomain enzyme, with glycerol‐3‐phosphate dehydrogenase and phosphatase activities, is involved in a chloroplastic pathway for glycerol synthesis in Chlamydomonas reinhardtii. The Plant Journal 2017, 90: 1079-1092. PMID: 28273364, DOI: 10.1111/tpj.13530.Peer-Reviewed Original ResearchConceptsMultidomain enzymeNitrogen deprivationPhosphatase activityGreen alga C.Dihydroxyacetone phosphateGlycerol synthesisGlycerol-3-phosphate dehydrogenaseHigh salinityCore chlorophytesPhosphatase motifPlastid pathwayChloroplastic pathwayAlgal speciesDehydrogenase domainChlamydomonas reinhardtiiChlamydomonas cellsMembrane glycerolipidsHyperosmotic stressCompatible solutesTAG accumulationBifunctional enzymeAlgal metabolismHypertonic stressFusion proteinTriacylglycerol accumulation