2016
Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders
Lester KJ, Roberts S, Keers R, Coleman JR, Breen G, Wong CC, Xu X, Arendt K, Blatter-Meunier J, Bögels S, Cooper P, Creswell C, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Krause K, Lyneham HJ, McKinnon A, Morris T, Nauta MH, Rapee RM, Rey Y, Schneider S, Schneider SC, Silverman WK, Smith P, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Eley TC. Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. The British Journal Of Psychiatry 2016, 208: 182-188. PMID: 26294368, PMCID: PMC4837384, DOI: 10.1192/bjp.bp.114.154997.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCBT outcomeChild anxietyAnxiety disordersChild anxiety disordersMore positive outcomesShort-allele homozygotesPositive treatment outcomesPsychological therapiesDisorder outcomesPositive outcomesTreatment studiesHomogenous sampleMixed resultsAnxietyMixed effects modelsNon-significant effectTreatment outcomesCohort 2DisordersSignificant associationFuture studiesOutcomesAssociationTherapy
2015
Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders
Wergeland GJ, Fjermestad KW, Marin CE, Bjelland I, Haugland BS, Silverman WK, Öst LG, Bjaastad JF, Oeding K, Havik OE, Heiervang ER. Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders. Behaviour Research And Therapy 2015, 76: 1-12. PMID: 26583954, DOI: 10.1016/j.brat.2015.11.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChild-rated anxiety symptomsParent internalizing symptomsAnxiety disordersAnxiety symptomsCBT programInternalizing symptomsSocial phobiaBehavioral therapyLower family social classPrimary anxiety disorderSeparation anxiety disorderPositive treatment outcomesFamily social classChildren of parentsAnxious childrenEffectiveness trialChildren's motivationParent factorsSeparation anxietyTreatment outcomesSymptom levelsRecent effectiveness studiesPoor outcomePhobia